Case of Gnathostomiasis in Beijing, China

Dong Ming Li Department of Dermatology, Peking University Third Hospital, Beijing, People’s Republic of China; Tropical Institute of Beijing, Beijing, People’s Republic of China; Division of Parasitology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Kiyotake, Miyazaki, Japan; Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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Xue Rong Chen Department of Dermatology, Peking University Third Hospital, Beijing, People’s Republic of China; Tropical Institute of Beijing, Beijing, People’s Republic of China; Division of Parasitology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Kiyotake, Miyazaki, Japan; Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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Jing Song Zhou Department of Dermatology, Peking University Third Hospital, Beijing, People’s Republic of China; Tropical Institute of Beijing, Beijing, People’s Republic of China; Division of Parasitology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Kiyotake, Miyazaki, Japan; Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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Zhi Biao Xu Department of Dermatology, Peking University Third Hospital, Beijing, People’s Republic of China; Tropical Institute of Beijing, Beijing, People’s Republic of China; Division of Parasitology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Kiyotake, Miyazaki, Japan; Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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Yukifumi Nawa Department of Dermatology, Peking University Third Hospital, Beijing, People’s Republic of China; Tropical Institute of Beijing, Beijing, People’s Republic of China; Division of Parasitology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Kiyotake, Miyazaki, Japan; Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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Paron Dekumyoy Department of Dermatology, Peking University Third Hospital, Beijing, People’s Republic of China; Tropical Institute of Beijing, Beijing, People’s Republic of China; Division of Parasitology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Kiyotake, Miyazaki, Japan; Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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A 59-year-old woman sought treatment of for creeping eruption and erythematous plaques associated with high fever and systemic symptoms. She had a history of eating undercooked freshwater fish raised in Beijing 10 days before admission and reported no travel during the previous year. Blood examination showed eosinophila and ultrasonography detected multiple hypoechoic areas in the liver and spleen. Western blot test detected specific antibodies to the larvae of Gnathostoma spinigerum. Cutaneous and visceral larva migrations associated with G. spinigerum were diagnosed. Twenty-three cases in 12 provinces have been reported in the Chinese literature but none have been reported in English.

Author Notes

  • 1

    Nawa Y, 1991. Historical review and current status of gnathostomiasis in Asia. Southeast Asian J Trop Med Public Health 22 (Suppl):217–219.

  • 2

    Li JH, Cui Q, Bao L, 2003. A case of alimentary tract hemorrhage associated with Gnathostoma spinifera.Chin J Parasitol Parasitic Dis 21 :344.

  • 3

    Fu XH, Zhou XY, Li X, 1999. Gnathostomiasis in the lung. Chin J Parasitic Dis Contr 12 :142.

  • 4

    Koga M, Ishii Y, Lou YS, Higo H, Fujino T, Huang WC, 1996. A survey of Gnathostoma larvae in fresh water fish in the valley of the Yangtze River and morphological characteristics of the recovered larvae. Southeast Asian J Trop Med Public Health 27 :542–547.

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  • 5

    Tapchaisri P, Nopparatana C, Chaicumpa W, Setasuban P, 1991. Specific antigen of Gnathostoma spinigerum for immunodiagnosis of human gnathostomiasis. Int J Parasitol l21:315–319.

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