A Bentonite Flocculation Test for the Diagnosis of Hydatid Disease in Man and Animals

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  • U. S. Department of Health, Education and Welfare, Public Health Service, Communicable Disease Center, Atlanta, Georgia


Comparison of results obtained by complement-fixation test and bentonite flocculation (BF) test on 4,148 sera from man and animals shows that the BF test gave more positive reactions and suggests that reactions below 1:10 titer may be nonspecific. Of a number of antigens tested on the bentonite particles, scolices antigens may prove to be more specific for use in the BF test than hydatid fluid antigen.

Although the BF procedure as a diagnostic test for human disease has been used with only 35 proven cases of echinococcus disease, it appears to merit consideration as another serological tool.

Author Notes

Present address: Department of Medical Zoology, 406th Medical General Laboratory, APO 343, San Francisco, California.