Gopinath R, Ostrowski M, Justement SJ, Fauci AS, Nutman TB, 2000. Filarial infections increase susceptibility to human immunodeficiency virus infection in peripheral blood mononuclear cells in vitro. J Infect Dis 182 :1804–1808.
Nielsen NO, Simonsen PE, Magnussen P, Magesa S, Friis H, 2006. Cross-sectional relationship between HIV, lymphatic filariasis and other parasitic infections in adults in coastal northeastern Tanzania. Trans R Soc Trop Med Hyg 100 :543–550.
Lipner EM, Gopi PG, Subramani R, Kolappan C, Sadacharam K, Prevots DR, Narayanan PR, Nutman TB, Kumaraswami V, 2006. Coincident filarial, intestinal helminth, and mycobacterial infection: helminths fail to influence tuberculin reactivity, but BCG influences hookworm prevalence. Am J Trop Med Hyg 74 :841–847.
UNAIDS. Press Release: 2.5 Million People Living with HIV in India. Available at: http://www.unaids.org/en/MediaCentre/PressMaterials/FeatureStory/20070704_India_new_data.asp. Accessed August 20, 2007.
Steinbrook R, 2007. HIV in India—A complex epidemic. N Engl J Med 356 :1089–1093.
WHO, UNAIDS, UNICEF, 2007. Towards Universal Access: Scaling up Priority HIV/AIDS Interventions in the Health Sector. Progress Report. Geneva: World Health Organization, 53.
NACO, 2007. Number of Patients on ART Cross 1 Lakh Mark. NACO News 3(3): 3. Available at: http://www.nacoonline.org/Quick_Links/Publication/NewsLetter/. Accessed on December 5, 2007.
Weil GJ, Lammie PJ, Weiss N, 2007. The ICT filariasis test: a rapid format antigen test for diagnosis of Bancroftian filariasis. Parasitol Today 13 :401–404.
More SJ, Copeman DB, 1990. A highly specific and sensitive monoclonal antibody-based ELISA for the detection of circulating antigen in Bancroftian filariasis. Trop Med Parasitol 41 :403–406.
Wolday D, Mayaan S, Mariam ZG, Berhee N, Seboxa T, Britton S, Galai N, Landay A, Bentwich Z, 2002. Treatment of intestinal worms is associated with decreased HIV plasma viral load. J Acquir Immune Defic Syndr 31 :56–62.
Modjarrad K, Zulu I, Redden DT, Njobvu L, Lane HC, Bentwich Z, Vermund SH, 2005. Treatment of intestinal helminths does not reduce plasma concentrations of HIV-1 RNA in coinfected Zambian adults. J Infect Dis 192 :1277–1283.
Brown M, Kizza M, Watera C, Quigley MA, Rowland S, Hughes P, Whitworth JA, Elliott AM, 2004. Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda. J Infect Dis 190 :1869–1879.
Kipp W, Bamuhiiga J, Rubaale T, 2003. Simulium neavei-transmitted onchocerciasis: HIV infection increases severity of onchocercal skin disease in a small sample of patients. Trans R Soc Trop Med Hyg 97 :310–311.
Tawill SA, Gallin M, Erttmann KD, Kipp W, Bamuhiiga J, Buttner DW, 1996. Impaired antibody responses and loss of reactivity to Onchocerca volvulus antigens by HIV-seropositive onchocerciasis patients. Trans R Soc Trop Med Hyg 90 :85–89.
Nielsen NO, Friis H, Magnussen P, Krarup H, Magesa S, Simponsen PE, 2007. Co-infection with subclinical HIV and Wuchereria bancrofti, and the role of malaria and hookworms, in adult Tanzaniains: infection intensities, CD4/CD8 counts and cytokine responses. Trans R Soc Trop Med Hyg 101 :602–612.
Nielsen NO, Simonsen PE, Dalgaard P, Krarup H, Magnussen P, Magesa S, Friis H, 2007. Effect of diethylcarbamazine on HIV load, CD4%, and CD4/CD8 ratio in HIV-infected adult Tanzanians with or without lymphatic filariasis: randomized double-blind and placebo-controlled cross-over trial. Am J Trop Med Hyg 77 :507–513.
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The disease course of human immunodeficiency virus (HIV) is often altered by existing or newly acquired coinfections. Treatment or prevention of these concomitant infections often improves the quality and duration of life of HIV-infected persons. The impact of helminth infections on infections with HIV is less clear. However, HIV is frequently most problematic in areas where helminth infections are common. In advance of the widespread distribution of drugs for elimination of lymphatic filariasis, we assessed the prevalence of active Wuchereria bancrofti infection among HIV-positive patients in Chennai, India at two time points separated by four years. We found that the overall prevalence of W. bancrofti infections among HIV-positive persons was 5–9.5%, and there were no quantitative differences in circulating filarial antigen levels between HIV-positive and HIV-negative filarial-infected patients.