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Human Hydatid Disease in Peru Is Basically Restricted to Echinococcus granulosus Genotype G1

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  • 1 Department of Microbiology, School of Sciences, Universidad Peruana Cayetano Heredia, Lima, Peru; Departamento de Parasitología, Instituto Nacional de Enfermedades Infecciosas, “ANLIS Dr. Carlos G. Malbrán”, Buenos Aires, Argentina; Cysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Peru; Thoracic and Cardiovascular Surgery Program, Hospital Nacional Dos de Mayo, Lima, Peru; School of Veterinary Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru; Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland
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A molecular PCR study using DNA from 21 hydatid cysts was performed to determine which strain type is responsible for human infection in Peru. The mitochondrial cytochrome c oxidase subunit 1 (CO1) gene was amplified in 20 out of 21 samples, revealing that all but 1 sample (19/20, 95%) belonged to the common sheep strain (G1). The remaining samples belonged to the camel strain (G6). The G1 genotype was most frequently found in human cases of cystic hydatid disease (CHD) in Peru. Local control measures should focus primarily on decreasing dog and sheep infection rather than intermediate reservoirs.

Author Notes

Reprint requests: Hector H. Garcia, Department of Microbiology, Universidad Peruana Cayetano Heredia, Av. H. Delgado 430, SMP, Lima 31, Peru, Tel: 511-3287360, Fax: 511-3284038, E-mail: hgarcia@jhsph.edu.
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