ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1
Rudnick A, Lim TW, 1986. Dengue fever studies in Malaysia. Inst Med Res Malaysia Bull 23 :51–152.
-
2
Rudnick A, 1984. The ecology of the dengue virus complex in peninsular Malaysia. T. Pang, Pathmanatan R, eds. Proceedings of the International Conference on dengue/DHF. Kuala Lampur, Malaysia: University of Malaysia Press.
-
3
Saluzzo JF, Cornet M, Adam C, Eyraud M, Digoutte JP, 1986. Dengue 2 in eastern Senegal: serologic survey in simian and human populations, 1974–85. Bull Soc Pathol Exot Filiales 79 :313–322.
-
4
Rodhain F, 1991. The role of monkeys in the biology of dengue and yellow fever. Comp Immunol Microbiol Infect Dis 14 :9–19.
-
5
Diallo M, Ba Y, Sall AA, Diop OM, Ndione JA, Mondo M, Girault L, Mathiot C, 2003. Amplification of the sylvatic cycle of dengue virus type 2, Senegal, 1999–2000: entomologic findings and epidemiologic considerations. Emerg Infect Dis 9 :362–367.
-
6
Saluzzo JF, Cornet M, Castagnet P, Rey C, Digoutte JP, 1986. Isolation of dengue 2 and dengue 4 viruses from patients in Senegal. Trans R Soc Trop Med Hyg 80 :5.
-
7
Robin Y, Cornet M, Heme G, Le Gonidec G, 1980. Isolement du virus dela dengue au Senegal. Ann Virol 131 :149–154.
-
8
Carey DE, Causey OR, Reddy S, Cooke AR, 1971. Dengue viruses from febrile patients in Nigeria, 1964–68. Lancet 1 :105–106.
-
9
Vasilakis N, Tesh RB, Weaver SC, 2008. Sylvatic dengue virus type 2 activity in humans, Nigeria, 1966. Emerg Infect Dis 14 :502–504.
-
10
Wang E, Ni H, Xu R, Barrett AD, Watowich SJ, Gubler DJ, Weaver SC, 2000. Evolutionary relationships of endemic/ epidemic and sylvatic dengue viruses. J Virol 74 :3227–3234.
-
11
Moncayo AC, Fernandez Z, Ortiz D, Diallo M, Sall A, Hartman S, Davis CT, Coffey L, Mathiot CC, Tesh RB, Weaver SC, 2004. Dengue emergence and adaptation to peridomestic mosquitoes. Emerg Infect Dis 10 :1790–1796.
-
12
Diallo M, Sall AA, Moncayo AC, Ba Y, Fernandez Z, Ortiz D, Coffey LL, Mathiot C, Tesh RB, Weaver SC, 2005. Potential role of sylvatic and domestic African mosquito species in dengue emergence. Am J Trop Med Hyg 73 :445–449.
-
13
Vasilakis N, Shell EJ, Fokam EB, Mason PW, Hanley KA, Estes DM, Weaver SC, 2007. Potential of ancestral sylvatic dengue-2 viruses to re-emerge. Virology 358 :402–412.
-
14
Vasilakis N, Holmes EC, Fokam EB, Faye O, Diallo M, Sall AA, Weaver SC, 2007. Evolutionary processes among sylvatic dengue-2 viruses. J Virol 81 :9591–9595.
-
15
Blaney JE Jr, Durbin AP, Murphy BR, Whitehead SS, 2006. Development of a live attenuated dengue virus vaccine using reverse genetics. Viral Immunol 19 :10–32.
-
16
Durbin AP, McArthur JH, Marron JA, Blaney JE, Thumar B, Wanionek K, Murphy BR, Whitehead SS, 2006. rDEN2/ 4Delta30(ME), a live attenuated chimeric dengue serotype 2 vaccine is safe and highly immunogenic in healthy dengue-naive adults. Hum Vaccin 2 :255–260.
-
17
Deauvieau F, Sanchez V, Balas C, Kennel A, de Montfort A, Lang J, Guy B, 2007. Innate immune responses in human dendritic cells upon infection by chimeric yellow-fever dengue vaccine serotypes 1–4. Am J Trop Med Hyg 76 :144–154.
-
18
Guirakhoo F, Pugachev K, Zhang Z, Myers G, Levenbook I, Draper K, Lang J, Ocran S, Mitchell F, Parsons M, Brown N, Brandler S, Fournier C, Barrere B, Rizvi F, Travassos A, Nichols R, Trent D, Monath T, 2004. Safety and efficacy of chimeric yellow fever-dengue virus tetravalent vaccine formulations in nonhuman primates. J Virol 78 :4761–4775.
-
19
Durbin AP, McArthur J, Marron JA, Blaney JE Jr, Thumar B, Wanionek K, Murphy BR, Whitehead SS, 2006. The live attenuated dengue serotype 1 vaccine rDEN1Delta30 is safe and highly immunogenic in healthy adult volunteers. Hum Vaccin 2 :167–173.
-
20
Durbin AP, Whitehead SS, McArthur J, Perreault JR, Blaney JE Jr, Thumar B, Murphy BR, Karron RA, 2005. rDEN4delta30, a live attenuated dengue virus type 4 vaccine candidate, is safe, immunogenic, and highly infectious in healthy adult volunteers. J Infect Dis 191 :710–718.
-
21
Durbin AP, Karron RA, Sun W, Vaughn DW, Reynolds MJ, Perreault JR, Thumar B, Men R, Lai CJ, Elkins WR, Chanock RM, Murphy BR, Whitehead SS, 2001. Attenuation and immunogenicity in humans of a live dengue virus type-4 vaccine candidate with a 30 nucleotide deletion in its 3′-untranslated region. Am J Trop Med Hyg 65 :405–413.
-
22
Blaney JE Jr, Matro JM, Murphy BR, Whitehead SS, 2005. Recombinant, live-attenuated tetravalent dengue virus vaccine formulations induce a balanced, broad, and protective neutralizing antibody response against each of the four serotypes in rhesus monkeys. J Virol 79 :5516–5528.
-
23
Whitehead SS, Hanley KA, Blaney JE Jr, Gilmore LE, Elkins WR, Murphy BR, 2003. Substitution of the structural genes of dengue virus type 4 with those of type 2 results in chimeric vaccine candidates which are attenuated for mosquitoes, mice, and rhesus monkeys. Vaccine 21 :4307–4316.
-
24
Kuno G, Gubler DJ, Oliver A, 1993. Use of original’antigenic sin’ theory to determine the serotypes of previous dengue infections. Trans R Soc Trop Med Hyg 87 :103–105.
-
25
Halstead SB, Rojanasuphot S, Sangkawibha N, 1983. Original antigenic sin in dengue. Am J Trop Med Hyg 32 :154–156.
-
26
Chien LJ, Liao TL, Shu PY, Huang JH, Gubler DJ, Chang GJ, 2006. Development of real-time reverse transcriptase PCR assays to detect and serotype dengue viruses. J Clin Microbiol 44 :1295–1304.
-
27
Sabin AB, 1952. Research on dengue during World War II. Am J Trop Med Hyg 1 :30–50.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 760 | 707 | 35 |
| Full Text Views | 311 | 9 | 0 |
| PDF Downloads | 97 | 9 | 0 |
Antigenic Relationships between Sylvatic and Endemic Dengue Viruses
Nikos Vasilakis
Nikos Vasilakis
Center for Biodefense and Emerging Infectious Diseases, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Molecular Virology and Surveillance Laboratory, Centers for Disease Control and Prevention Dengue Branch, San Juan, Puerto Rico
Search for other papers by Nikos Vasilakis in
Current site
Google Scholar
PubMed
Search for other papers by Nikos Vasilakis in
Current site
Google Scholar
PubMed
Anna P. Durbin
Anna P. Durbin
Center for Biodefense and Emerging Infectious Diseases, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Molecular Virology and Surveillance Laboratory, Centers for Disease Control and Prevention Dengue Branch, San Juan, Puerto Rico
Search for other papers by Anna P. Durbin in
Current site
Google Scholar
PubMed
Search for other papers by Anna P. Durbin in
Current site
Google Scholar
PubMed
Amelia P. A. Travassos da Rosa
Amelia P. A. Travassos da Rosa
Center for Biodefense and Emerging Infectious Diseases, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Molecular Virology and Surveillance Laboratory, Centers for Disease Control and Prevention Dengue Branch, San Juan, Puerto Rico
Search for other papers by Amelia P. A. Travassos da Rosa in
Current site
Google Scholar
PubMed
Search for other papers by Amelia P. A. Travassos da Rosa in
Current site
Google Scholar
PubMed
Jorge L. Munoz-Jordan
Jorge L. Munoz-Jordan
Center for Biodefense and Emerging Infectious Diseases, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Molecular Virology and Surveillance Laboratory, Centers for Disease Control and Prevention Dengue Branch, San Juan, Puerto Rico
Search for other papers by Jorge L. Munoz-Jordan in
Current site
Google Scholar
PubMed
Search for other papers by Jorge L. Munoz-Jordan in
Current site
Google Scholar
PubMed
Robert B. Tesh
Robert B. Tesh
Center for Biodefense and Emerging Infectious Diseases, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Molecular Virology and Surveillance Laboratory, Centers for Disease Control and Prevention Dengue Branch, San Juan, Puerto Rico
Search for other papers by Robert B. Tesh in
Current site
Google Scholar
PubMed
Search for other papers by Robert B. Tesh in
Current site
Google Scholar
PubMed
Scott C. Weaver
Scott C. Weaver
Center for Biodefense and Emerging Infectious Diseases, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Molecular Virology and Surveillance Laboratory, Centers for Disease Control and Prevention Dengue Branch, San Juan, Puerto Rico
Search for other papers by Scott C. Weaver in
Current site
Google Scholar
PubMed
Search for other papers by Scott C. Weaver in
Current site
Google Scholar
PubMed
Sylvatic dengue viruses (DENVs) are transmitted between non-human primates and arboreal Aedes spp. mosquitoes in Southeast Asia and west Africa. Recent evidence suggests that the risk for re-emergence of sylvatic DENV into the urban endemic/epidemic cycle may be high, which could limit the potential for eradicating the human transmission cycle with vaccines now under development. We assessed the likelihood of sylvatic DENV re-emergence in the face of immunity to current endemic strains or vaccines by evaluating the neutralization capacity of sera from DENV vaccinees and convalescent patients after primary infection with DENV-2 and DENV-3 serotypes. Our data indicate robust homotypic cross-immunity between human sera and sylvatic DENV strains, but limited heterotypic neutralization. Should a licensed vaccine lead to the eradication of the urban transmission cycle in the future, re-emergence of sylvatic strains into the urban cycle would be limited by homotypic immunity mediated by virus-neutralizing antibodies.
Author Notes
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1
Rudnick A, Lim TW, 1986. Dengue fever studies in Malaysia. Inst Med Res Malaysia Bull 23 :51–152.
-
2
Rudnick A, 1984. The ecology of the dengue virus complex in peninsular Malaysia. T. Pang, Pathmanatan R, eds. Proceedings of the International Conference on dengue/DHF. Kuala Lampur, Malaysia: University of Malaysia Press.
-
3
Saluzzo JF, Cornet M, Adam C, Eyraud M, Digoutte JP, 1986. Dengue 2 in eastern Senegal: serologic survey in simian and human populations, 1974–85. Bull Soc Pathol Exot Filiales 79 :313–322.
-
4
Rodhain F, 1991. The role of monkeys in the biology of dengue and yellow fever. Comp Immunol Microbiol Infect Dis 14 :9–19.
-
5
Diallo M, Ba Y, Sall AA, Diop OM, Ndione JA, Mondo M, Girault L, Mathiot C, 2003. Amplification of the sylvatic cycle of dengue virus type 2, Senegal, 1999–2000: entomologic findings and epidemiologic considerations. Emerg Infect Dis 9 :362–367.
-
6
Saluzzo JF, Cornet M, Castagnet P, Rey C, Digoutte JP, 1986. Isolation of dengue 2 and dengue 4 viruses from patients in Senegal. Trans R Soc Trop Med Hyg 80 :5.
-
7
Robin Y, Cornet M, Heme G, Le Gonidec G, 1980. Isolement du virus dela dengue au Senegal. Ann Virol 131 :149–154.
-
8
Carey DE, Causey OR, Reddy S, Cooke AR, 1971. Dengue viruses from febrile patients in Nigeria, 1964–68. Lancet 1 :105–106.
-
9
Vasilakis N, Tesh RB, Weaver SC, 2008. Sylvatic dengue virus type 2 activity in humans, Nigeria, 1966. Emerg Infect Dis 14 :502–504.
-
10
Wang E, Ni H, Xu R, Barrett AD, Watowich SJ, Gubler DJ, Weaver SC, 2000. Evolutionary relationships of endemic/ epidemic and sylvatic dengue viruses. J Virol 74 :3227–3234.
-
11
Moncayo AC, Fernandez Z, Ortiz D, Diallo M, Sall A, Hartman S, Davis CT, Coffey L, Mathiot CC, Tesh RB, Weaver SC, 2004. Dengue emergence and adaptation to peridomestic mosquitoes. Emerg Infect Dis 10 :1790–1796.
-
12
Diallo M, Sall AA, Moncayo AC, Ba Y, Fernandez Z, Ortiz D, Coffey LL, Mathiot C, Tesh RB, Weaver SC, 2005. Potential role of sylvatic and domestic African mosquito species in dengue emergence. Am J Trop Med Hyg 73 :445–449.
-
13
Vasilakis N, Shell EJ, Fokam EB, Mason PW, Hanley KA, Estes DM, Weaver SC, 2007. Potential of ancestral sylvatic dengue-2 viruses to re-emerge. Virology 358 :402–412.
-
14
Vasilakis N, Holmes EC, Fokam EB, Faye O, Diallo M, Sall AA, Weaver SC, 2007. Evolutionary processes among sylvatic dengue-2 viruses. J Virol 81 :9591–9595.
-
15
Blaney JE Jr, Durbin AP, Murphy BR, Whitehead SS, 2006. Development of a live attenuated dengue virus vaccine using reverse genetics. Viral Immunol 19 :10–32.
-
16
Durbin AP, McArthur JH, Marron JA, Blaney JE, Thumar B, Wanionek K, Murphy BR, Whitehead SS, 2006. rDEN2/ 4Delta30(ME), a live attenuated chimeric dengue serotype 2 vaccine is safe and highly immunogenic in healthy dengue-naive adults. Hum Vaccin 2 :255–260.
-
17
Deauvieau F, Sanchez V, Balas C, Kennel A, de Montfort A, Lang J, Guy B, 2007. Innate immune responses in human dendritic cells upon infection by chimeric yellow-fever dengue vaccine serotypes 1–4. Am J Trop Med Hyg 76 :144–154.
-
18
Guirakhoo F, Pugachev K, Zhang Z, Myers G, Levenbook I, Draper K, Lang J, Ocran S, Mitchell F, Parsons M, Brown N, Brandler S, Fournier C, Barrere B, Rizvi F, Travassos A, Nichols R, Trent D, Monath T, 2004. Safety and efficacy of chimeric yellow fever-dengue virus tetravalent vaccine formulations in nonhuman primates. J Virol 78 :4761–4775.
-
19
Durbin AP, McArthur J, Marron JA, Blaney JE Jr, Thumar B, Wanionek K, Murphy BR, Whitehead SS, 2006. The live attenuated dengue serotype 1 vaccine rDEN1Delta30 is safe and highly immunogenic in healthy adult volunteers. Hum Vaccin 2 :167–173.
-
20
Durbin AP, Whitehead SS, McArthur J, Perreault JR, Blaney JE Jr, Thumar B, Murphy BR, Karron RA, 2005. rDEN4delta30, a live attenuated dengue virus type 4 vaccine candidate, is safe, immunogenic, and highly infectious in healthy adult volunteers. J Infect Dis 191 :710–718.
-
21
Durbin AP, Karron RA, Sun W, Vaughn DW, Reynolds MJ, Perreault JR, Thumar B, Men R, Lai CJ, Elkins WR, Chanock RM, Murphy BR, Whitehead SS, 2001. Attenuation and immunogenicity in humans of a live dengue virus type-4 vaccine candidate with a 30 nucleotide deletion in its 3′-untranslated region. Am J Trop Med Hyg 65 :405–413.
-
22
Blaney JE Jr, Matro JM, Murphy BR, Whitehead SS, 2005. Recombinant, live-attenuated tetravalent dengue virus vaccine formulations induce a balanced, broad, and protective neutralizing antibody response against each of the four serotypes in rhesus monkeys. J Virol 79 :5516–5528.
-
23
Whitehead SS, Hanley KA, Blaney JE Jr, Gilmore LE, Elkins WR, Murphy BR, 2003. Substitution of the structural genes of dengue virus type 4 with those of type 2 results in chimeric vaccine candidates which are attenuated for mosquitoes, mice, and rhesus monkeys. Vaccine 21 :4307–4316.
-
24
Kuno G, Gubler DJ, Oliver A, 1993. Use of original’antigenic sin’ theory to determine the serotypes of previous dengue infections. Trans R Soc Trop Med Hyg 87 :103–105.
-
25
Halstead SB, Rojanasuphot S, Sangkawibha N, 1983. Original antigenic sin in dengue. Am J Trop Med Hyg 32 :154–156.
-
26
Chien LJ, Liao TL, Shu PY, Huang JH, Gubler DJ, Chang GJ, 2006. Development of real-time reverse transcriptase PCR assays to detect and serotype dengue viruses. J Clin Microbiol 44 :1295–1304.
-
27
Sabin AB, 1952. Research on dengue during World War II. Am J Trop Med Hyg 1 :30–50.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 760 | 707 | 35 |
| Full Text Views | 311 | 9 | 0 |
| PDF Downloads | 97 | 9 | 0 |