ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1
Noma M, Nwoke BE, Nutall I, Tambala PA, Enyong P, Namsenmo A, Remme J, Amazigo UV, Kale OO, Seketeli A, 2002. Rapid epidemiological mapping of onchocerciasis (REMO): its application by the African Programme for Onchocerciasis Control (APOC). Ann Trop Med Parasitol 96 (Suppl 1):S29–S39.
-
2
Kaiser C, Kipp W, Asaba G, Mugisa C, Kabagambe G, Rating D, Leichsenring M, 1996. The prevalence of epilepsy follows the distribution of onchocerciasis in a west Uganda focus. Bull World Health Organ 74 :361–367.
-
3
Benoit M, Boussinesq M, Druet-Cabanac MI, Kamgno J, Bouteille B, Preux P, 2006. Onchocercerciasis-related epilepsy? Prospects at a time of uncertainty. Trends Parasitol 22 :17–20.
-
4
Phiri IK, Ngowi H, Afonso S, Matenga E, Boa M, Mukaratirwa S, Githigia S, Saimo M, Sikasunge C, Maingi N, Lubega GW, Kassuku A, Michael L, Siziya S, Krecek RCK, Noormahomed E, Vilhena M, Dorny PA, Willingham L III, 2003. The emergence of Taenia solium cysticercosis in Eastern and Southern Africa as a serious agricultural problem and public health risk. Acta Trop 87 :13–23.
-
5
Garcia HG, Gonzalez I, Mija L, 2007. Neurocysticercosis uncovered by single-dose albendazole. New Engl J Med 356 :1277–1278.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 0 | 0 | 0 |
| Full Text Views | 216 | 103 | 1 |
| PDF Downloads | 51 | 30 | 1 |
Could Neurocysticercosis Be the Cause of “Onchocerciasis-Associated” Epileptic Seizures?
We conducted a nodule prevalence survey in four onchocerciasis sentinel communities in Moyo and two in Kanungu districts of Uganda. Seven (33.3%) out of 21 excised “onchocercomas” (nodules) in Moyo District and excised onchocercomas from four of six persons in Kanungu District turned out to be cysts of Taenia solium. We concluded that the prediction of nodule prevalence for noninvasive rapid epidemiologic assessment (REA) to target areas for mass chemotherapy with ivermectin in the African Program for Onchocerciasis Control (APOC) supported areas may have been influenced by other pathologies. T. solium infection may be the main cause of “onchocerciasis-associated epileptic seizures” in many onchocerciasis endemic communities that have been causally linked to onchocerciasis. Lastly, widespread neurocysticercosis may be a concern in mass treatment programs that provide praziquantel (for managing schistosomiasis) or albendazole (for managing intestinal worms or lymphatic filariasis) because these drugs may kill cerebral cysticerci, resulting in severe adverse events.