Seroprevalence of Chikungunya Virus (CHIKV) Infection on Lamu Island, Kenya, October 2004

Kibet Sergon Field Epidemiology and Laboratory Training Program, Nairobi, Kenya; Disease Outbreak Management Unit, Ministry of Health, Nairobi, Kenya; US Army Medical Research Unit Kenya, Nairobi, Kenya; International Emerging Infections Program, Nairobi, Kenya; Ministry of Health, Lamu, Kenya; Central Bureau of Statistics, Mombasa, Kenya; Kenya Medical Research Institute, Nairobi, Kenya

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Charles Njuguna Field Epidemiology and Laboratory Training Program, Nairobi, Kenya; Disease Outbreak Management Unit, Ministry of Health, Nairobi, Kenya; US Army Medical Research Unit Kenya, Nairobi, Kenya; International Emerging Infections Program, Nairobi, Kenya; Ministry of Health, Lamu, Kenya; Central Bureau of Statistics, Mombasa, Kenya; Kenya Medical Research Institute, Nairobi, Kenya

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Rosalia Kalani Field Epidemiology and Laboratory Training Program, Nairobi, Kenya; Disease Outbreak Management Unit, Ministry of Health, Nairobi, Kenya; US Army Medical Research Unit Kenya, Nairobi, Kenya; International Emerging Infections Program, Nairobi, Kenya; Ministry of Health, Lamu, Kenya; Central Bureau of Statistics, Mombasa, Kenya; Kenya Medical Research Institute, Nairobi, Kenya

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Victor Ofula Field Epidemiology and Laboratory Training Program, Nairobi, Kenya; Disease Outbreak Management Unit, Ministry of Health, Nairobi, Kenya; US Army Medical Research Unit Kenya, Nairobi, Kenya; International Emerging Infections Program, Nairobi, Kenya; Ministry of Health, Lamu, Kenya; Central Bureau of Statistics, Mombasa, Kenya; Kenya Medical Research Institute, Nairobi, Kenya

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Clayton Onyango Field Epidemiology and Laboratory Training Program, Nairobi, Kenya; Disease Outbreak Management Unit, Ministry of Health, Nairobi, Kenya; US Army Medical Research Unit Kenya, Nairobi, Kenya; International Emerging Infections Program, Nairobi, Kenya; Ministry of Health, Lamu, Kenya; Central Bureau of Statistics, Mombasa, Kenya; Kenya Medical Research Institute, Nairobi, Kenya

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Limbaso S. Konongoi Field Epidemiology and Laboratory Training Program, Nairobi, Kenya; Disease Outbreak Management Unit, Ministry of Health, Nairobi, Kenya; US Army Medical Research Unit Kenya, Nairobi, Kenya; International Emerging Infections Program, Nairobi, Kenya; Ministry of Health, Lamu, Kenya; Central Bureau of Statistics, Mombasa, Kenya; Kenya Medical Research Institute, Nairobi, Kenya

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Sheryl Bedno Field Epidemiology and Laboratory Training Program, Nairobi, Kenya; Disease Outbreak Management Unit, Ministry of Health, Nairobi, Kenya; US Army Medical Research Unit Kenya, Nairobi, Kenya; International Emerging Infections Program, Nairobi, Kenya; Ministry of Health, Lamu, Kenya; Central Bureau of Statistics, Mombasa, Kenya; Kenya Medical Research Institute, Nairobi, Kenya

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Heather Burke Field Epidemiology and Laboratory Training Program, Nairobi, Kenya; Disease Outbreak Management Unit, Ministry of Health, Nairobi, Kenya; US Army Medical Research Unit Kenya, Nairobi, Kenya; International Emerging Infections Program, Nairobi, Kenya; Ministry of Health, Lamu, Kenya; Central Bureau of Statistics, Mombasa, Kenya; Kenya Medical Research Institute, Nairobi, Kenya

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Athman M. Dumilla Field Epidemiology and Laboratory Training Program, Nairobi, Kenya; Disease Outbreak Management Unit, Ministry of Health, Nairobi, Kenya; US Army Medical Research Unit Kenya, Nairobi, Kenya; International Emerging Infections Program, Nairobi, Kenya; Ministry of Health, Lamu, Kenya; Central Bureau of Statistics, Mombasa, Kenya; Kenya Medical Research Institute, Nairobi, Kenya

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Joseph Konde Field Epidemiology and Laboratory Training Program, Nairobi, Kenya; Disease Outbreak Management Unit, Ministry of Health, Nairobi, Kenya; US Army Medical Research Unit Kenya, Nairobi, Kenya; International Emerging Infections Program, Nairobi, Kenya; Ministry of Health, Lamu, Kenya; Central Bureau of Statistics, Mombasa, Kenya; Kenya Medical Research Institute, Nairobi, Kenya

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M. Kariuki Njenga Field Epidemiology and Laboratory Training Program, Nairobi, Kenya; Disease Outbreak Management Unit, Ministry of Health, Nairobi, Kenya; US Army Medical Research Unit Kenya, Nairobi, Kenya; International Emerging Infections Program, Nairobi, Kenya; Ministry of Health, Lamu, Kenya; Central Bureau of Statistics, Mombasa, Kenya; Kenya Medical Research Institute, Nairobi, Kenya

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Rosemary Sang Field Epidemiology and Laboratory Training Program, Nairobi, Kenya; Disease Outbreak Management Unit, Ministry of Health, Nairobi, Kenya; US Army Medical Research Unit Kenya, Nairobi, Kenya; International Emerging Infections Program, Nairobi, Kenya; Ministry of Health, Lamu, Kenya; Central Bureau of Statistics, Mombasa, Kenya; Kenya Medical Research Institute, Nairobi, Kenya

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Robert F. Breiman Field Epidemiology and Laboratory Training Program, Nairobi, Kenya; Disease Outbreak Management Unit, Ministry of Health, Nairobi, Kenya; US Army Medical Research Unit Kenya, Nairobi, Kenya; International Emerging Infections Program, Nairobi, Kenya; Ministry of Health, Lamu, Kenya; Central Bureau of Statistics, Mombasa, Kenya; Kenya Medical Research Institute, Nairobi, Kenya

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An outbreak of Chikungunya virus (CHIKV) disease associated with high fever and severe protracted arthralgias was detected in Lamu, Kenya, peaking in July 2004. At least 1,300 cases were documented. We conducted a seroprevalence study to define the magnitude of transmission on Lamu Island. We conducted a systematic cross-sectional survey. We administered questionnaires and tested 288 sera from Lamu residents for IgM and IgG antibodies to CHIKV. Chikungunya virus infection (seropositivity) was defined as a person with IgG and/or IgM antibodies to CHIKV. IgM antibodies to CHIKV were detected in 18% (53/288) and IgG antibodies in 72% (206/288); IgM and/or IgG antibodies were present in 75% (215/288). The seroprevalence findings suggested that the outbreak was widespread, affecting 75% of the Lamu population; extrapolating the findings to the entire population, 13,500 (95% CI, 12,458–14328) were affected. Vector control strategies are needed to control the spread of this mosquito-borne infection.

Author Notes

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