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Fatal Systemic Infection with Multifocal Liver and Lung Nodules Caused by Brucella abortus

Keo Woon ParkDivision of Infectious Diseases, Departments of Internal Medicine and Research Center for Resistant Cells, Chosun University College of Medicine, Gwangju, Korea; Department of Laboratory Medicine, Chosun University College of Medicine, Gwangju, Korea; Division of Zoonoses, Center for Immunology and Pathology, Korea Center for Disease Control and Prevention, Seoul, Korea; Department of Clincal Pathology, Gwangju Health College, Gwangju, Korea; Departments of Pediatrics, Seonam University College of Medicine, Namwon, Korea

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Dong-Min KimDivision of Infectious Diseases, Departments of Internal Medicine and Research Center for Resistant Cells, Chosun University College of Medicine, Gwangju, Korea; Department of Laboratory Medicine, Chosun University College of Medicine, Gwangju, Korea; Division of Zoonoses, Center for Immunology and Pathology, Korea Center for Disease Control and Prevention, Seoul, Korea; Department of Clincal Pathology, Gwangju Health College, Gwangju, Korea; Departments of Pediatrics, Seonam University College of Medicine, Namwon, Korea

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Chi Young ParkDivision of Infectious Diseases, Departments of Internal Medicine and Research Center for Resistant Cells, Chosun University College of Medicine, Gwangju, Korea; Department of Laboratory Medicine, Chosun University College of Medicine, Gwangju, Korea; Division of Zoonoses, Center for Immunology and Pathology, Korea Center for Disease Control and Prevention, Seoul, Korea; Department of Clincal Pathology, Gwangju Health College, Gwangju, Korea; Departments of Pediatrics, Seonam University College of Medicine, Namwon, Korea

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Hyun Lee KimDivision of Infectious Diseases, Departments of Internal Medicine and Research Center for Resistant Cells, Chosun University College of Medicine, Gwangju, Korea; Department of Laboratory Medicine, Chosun University College of Medicine, Gwangju, Korea; Division of Zoonoses, Center for Immunology and Pathology, Korea Center for Disease Control and Prevention, Seoul, Korea; Department of Clincal Pathology, Gwangju Health College, Gwangju, Korea; Departments of Pediatrics, Seonam University College of Medicine, Namwon, Korea

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Sook Jin JangDivision of Infectious Diseases, Departments of Internal Medicine and Research Center for Resistant Cells, Chosun University College of Medicine, Gwangju, Korea; Department of Laboratory Medicine, Chosun University College of Medicine, Gwangju, Korea; Division of Zoonoses, Center for Immunology and Pathology, Korea Center for Disease Control and Prevention, Seoul, Korea; Department of Clincal Pathology, Gwangju Health College, Gwangju, Korea; Departments of Pediatrics, Seonam University College of Medicine, Namwon, Korea

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Young Sil ChoiDivision of Infectious Diseases, Departments of Internal Medicine and Research Center for Resistant Cells, Chosun University College of Medicine, Gwangju, Korea; Department of Laboratory Medicine, Chosun University College of Medicine, Gwangju, Korea; Division of Zoonoses, Center for Immunology and Pathology, Korea Center for Disease Control and Prevention, Seoul, Korea; Department of Clincal Pathology, Gwangju Health College, Gwangju, Korea; Departments of Pediatrics, Seonam University College of Medicine, Namwon, Korea

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Mi-Yeoun ParkDivision of Infectious Diseases, Departments of Internal Medicine and Research Center for Resistant Cells, Chosun University College of Medicine, Gwangju, Korea; Department of Laboratory Medicine, Chosun University College of Medicine, Gwangju, Korea; Division of Zoonoses, Center for Immunology and Pathology, Korea Center for Disease Control and Prevention, Seoul, Korea; Department of Clincal Pathology, Gwangju Health College, Gwangju, Korea; Departments of Pediatrics, Seonam University College of Medicine, Namwon, Korea

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Hyeon-Je SongDivision of Infectious Diseases, Departments of Internal Medicine and Research Center for Resistant Cells, Chosun University College of Medicine, Gwangju, Korea; Department of Laboratory Medicine, Chosun University College of Medicine, Gwangju, Korea; Division of Zoonoses, Center for Immunology and Pathology, Korea Center for Disease Control and Prevention, Seoul, Korea; Department of Clincal Pathology, Gwangju Health College, Gwangju, Korea; Departments of Pediatrics, Seonam University College of Medicine, Namwon, Korea

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Seung-Hyun LeeDivision of Infectious Diseases, Departments of Internal Medicine and Research Center for Resistant Cells, Chosun University College of Medicine, Gwangju, Korea; Department of Laboratory Medicine, Chosun University College of Medicine, Gwangju, Korea; Division of Zoonoses, Center for Immunology and Pathology, Korea Center for Disease Control and Prevention, Seoul, Korea; Department of Clincal Pathology, Gwangju Health College, Gwangju, Korea; Departments of Pediatrics, Seonam University College of Medicine, Namwon, Korea

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We experienced a fatal case caused by Brucella abortus with multifocal necrosis confirmed by culture and polymerase chain reaction. Our case highlights that the clinician should be aware of the potential for fatality when a patient with brucellosis shows dissemination of abscess or nodules with no calcification in the liver, lung, pleura, and spine.

Author Notes

Reprint requests: Dong-Min Kim, Division of Infectious Diseases, Department of Internal Medicine, Chosun University College of Medicine, 588 Seosuk-dong, Dong-gu, Gwangju, 501-717, Republic of Korea. E-mail: drongkim@chosun.ac.kr.
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