FIELD COMPARISON OF IMMUNODIAGNOSTIC AND PARASITOLOGICAL TECHNIQUES FOR THE DETECTION OF SCHISTOSOMIASIS JAPONICA IN THE PEOPLE’S REPUBLIC OF CHINA

YI-BIAO ZHOU Department of Epidemiology, School of Public Health, Fudan University, Shanghai, People’s Republic of China; Xuhui Center for Disease Control and Prevent, Shanghai, People’s Republic of China; Anhui Provincial Institute of Parasitic Diseases, Wuhu, People’s Republic of China; Key Laboratory of Public Health Safety, Fudan University, Ministry of Education, People’s Republic of China

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MEI-XIA YANG Department of Epidemiology, School of Public Health, Fudan University, Shanghai, People’s Republic of China; Xuhui Center for Disease Control and Prevent, Shanghai, People’s Republic of China; Anhui Provincial Institute of Parasitic Diseases, Wuhu, People’s Republic of China; Key Laboratory of Public Health Safety, Fudan University, Ministry of Education, People’s Republic of China

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QI-ZHI WANG Department of Epidemiology, School of Public Health, Fudan University, Shanghai, People’s Republic of China; Xuhui Center for Disease Control and Prevent, Shanghai, People’s Republic of China; Anhui Provincial Institute of Parasitic Diseases, Wuhu, People’s Republic of China; Key Laboratory of Public Health Safety, Fudan University, Ministry of Education, People’s Republic of China

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GEN-MING ZHAO Department of Epidemiology, School of Public Health, Fudan University, Shanghai, People’s Republic of China; Xuhui Center for Disease Control and Prevent, Shanghai, People’s Republic of China; Anhui Provincial Institute of Parasitic Diseases, Wuhu, People’s Republic of China; Key Laboratory of Public Health Safety, Fudan University, Ministry of Education, People’s Republic of China

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JIAN-GUO WEI Department of Epidemiology, School of Public Health, Fudan University, Shanghai, People’s Republic of China; Xuhui Center for Disease Control and Prevent, Shanghai, People’s Republic of China; Anhui Provincial Institute of Parasitic Diseases, Wuhu, People’s Republic of China; Key Laboratory of Public Health Safety, Fudan University, Ministry of Education, People’s Republic of China

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WEN-XIANG PENG Department of Epidemiology, School of Public Health, Fudan University, Shanghai, People’s Republic of China; Xuhui Center for Disease Control and Prevent, Shanghai, People’s Republic of China; Anhui Provincial Institute of Parasitic Diseases, Wuhu, People’s Republic of China; Key Laboratory of Public Health Safety, Fudan University, Ministry of Education, People’s Republic of China

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QING-WU JIANG Department of Epidemiology, School of Public Health, Fudan University, Shanghai, People’s Republic of China; Xuhui Center for Disease Control and Prevent, Shanghai, People’s Republic of China; Anhui Provincial Institute of Parasitic Diseases, Wuhu, People’s Republic of China; Key Laboratory of Public Health Safety, Fudan University, Ministry of Education, People’s Republic of China

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A total of 1,811 individuals from two villages located in the areas of China endemic for Schistosoma japonicum were analyzed by the Kato-Katz parasitologic examination, indirect hemagglutination assay (IHA), and enzyme-linked immunosorbent assay (ELISA). Statistical analysis of the results showed the κ indices ranged from 0.106 to 0.234 between IHA and the stool examination and ranged from 0.037 to 0.134 between ELISA and the fecal examination. The sensitivity value of the IHA was 83.7% in Village A and 92.3% in Village B; the specificity value of the IHA was 55.8% in Village A and 67.3% in Village B. The sensitivity value of the ELISA was 88.4% in Village A and 96.2% in Village B; the specificity value of the ELISA was 38.4% in both Village A and Village B. A search for a good diagnostic test that can be applied in field situations in China should be given high priority.

Author Notes

Reprint requests: Zhou Yi-biao, Department of Epidemiology, School of Public Health, Fudan University, Yixueyuan Road, Shanghai 200032, People’s Republic of China. E-mail: z_yibiao@hotmail.com.
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