HIGH SPATIAL RESOLUTION MAPPING OF MALARIA TRANSMISSION RISK IN THE GAMBIA, WEST AFRICA, USING LANDSAT TM SATELLITE IMAGERY

CLAUS BØGH DBL-Institute for Health Research and Development, Charlottenlund, Denmark; School of Biological and Biomedical Sciences, Durham University, Durham, United Kingdom; London School of Hygiene and Tropical Medicine, Bedford Square, London, United Kingdom; Hatfield Consultants, Vancouver, BC, Canada; Medical Research Council Laboratories, Fajara, The Gambia

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STEVEN W. LINDSAY DBL-Institute for Health Research and Development, Charlottenlund, Denmark; School of Biological and Biomedical Sciences, Durham University, Durham, United Kingdom; London School of Hygiene and Tropical Medicine, Bedford Square, London, United Kingdom; Hatfield Consultants, Vancouver, BC, Canada; Medical Research Council Laboratories, Fajara, The Gambia

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SIÂN E. CLARKE DBL-Institute for Health Research and Development, Charlottenlund, Denmark; School of Biological and Biomedical Sciences, Durham University, Durham, United Kingdom; London School of Hygiene and Tropical Medicine, Bedford Square, London, United Kingdom; Hatfield Consultants, Vancouver, BC, Canada; Medical Research Council Laboratories, Fajara, The Gambia

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ANDY DEAN DBL-Institute for Health Research and Development, Charlottenlund, Denmark; School of Biological and Biomedical Sciences, Durham University, Durham, United Kingdom; London School of Hygiene and Tropical Medicine, Bedford Square, London, United Kingdom; Hatfield Consultants, Vancouver, BC, Canada; Medical Research Council Laboratories, Fajara, The Gambia

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MUSA JAWARA DBL-Institute for Health Research and Development, Charlottenlund, Denmark; School of Biological and Biomedical Sciences, Durham University, Durham, United Kingdom; London School of Hygiene and Tropical Medicine, Bedford Square, London, United Kingdom; Hatfield Consultants, Vancouver, BC, Canada; Medical Research Council Laboratories, Fajara, The Gambia

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MARGARET PINDER DBL-Institute for Health Research and Development, Charlottenlund, Denmark; School of Biological and Biomedical Sciences, Durham University, Durham, United Kingdom; London School of Hygiene and Tropical Medicine, Bedford Square, London, United Kingdom; Hatfield Consultants, Vancouver, BC, Canada; Medical Research Council Laboratories, Fajara, The Gambia

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CHRISTOPHER J. THOMAS DBL-Institute for Health Research and Development, Charlottenlund, Denmark; School of Biological and Biomedical Sciences, Durham University, Durham, United Kingdom; London School of Hygiene and Tropical Medicine, Bedford Square, London, United Kingdom; Hatfield Consultants, Vancouver, BC, Canada; Medical Research Council Laboratories, Fajara, The Gambia

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Understanding local variability in malaria transmission risk is critically important when designing intervention or vaccine trials. Using a combination of field data, satellite image analysis, and GIS modeling, we developed a high-resolution map of malaria entomological inoculation rates (EIR) in The Gambia, West Africa. The analyses are based on the variation in exposure to malaria parasites experienced in 48 villages in 1996 and 21 villages in 1997. The entomological inoculation rate (EIR) varied from 0 to 166 infective bites per person per rainy season. Detailed field surveys identified the major Anopheles gambiae s.l. breeding habitats. These habitats were mapped by classification of a LANDSAT TM satellite image with an overall accuracy of 85%. Village EIRs decreased as a power function based on the breeding areas size and proximity. We use this relationship and the breeding habitats to map the variation in EIR over the entire 2500-km2 study area.

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