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A CASE OF ANAPHYLACTIC REACTION TO PRAZIQUANTEL TREATMENT

CHENGHUA SHENDepartment of Parasitology and Tropical Medicine, and Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul, Republic of Korea; Heilongjiang Provincial Zhaoyuanxian Center for Disease Control and Prevention, Zhaoyuan, People’s Republic of China; Department of Internal Medicine, Heilongjiang Provincial Zhaoyuan People’s Hospital, Zhaoyuan, People’s Republic of China

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MIN-HO CHOIDepartment of Parasitology and Tropical Medicine, and Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul, Republic of Korea; Heilongjiang Provincial Zhaoyuanxian Center for Disease Control and Prevention, Zhaoyuan, People’s Republic of China; Department of Internal Medicine, Heilongjiang Provincial Zhaoyuan People’s Hospital, Zhaoyuan, People’s Republic of China

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YOUNG MEE BAEDepartment of Parasitology and Tropical Medicine, and Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul, Republic of Korea; Heilongjiang Provincial Zhaoyuanxian Center for Disease Control and Prevention, Zhaoyuan, People’s Republic of China; Department of Internal Medicine, Heilongjiang Provincial Zhaoyuan People’s Hospital, Zhaoyuan, People’s Republic of China

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GUI YUDepartment of Parasitology and Tropical Medicine, and Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul, Republic of Korea; Heilongjiang Provincial Zhaoyuanxian Center for Disease Control and Prevention, Zhaoyuan, People’s Republic of China; Department of Internal Medicine, Heilongjiang Provincial Zhaoyuan People’s Hospital, Zhaoyuan, People’s Republic of China

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SHUHUA WANGDepartment of Parasitology and Tropical Medicine, and Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul, Republic of Korea; Heilongjiang Provincial Zhaoyuanxian Center for Disease Control and Prevention, Zhaoyuan, People’s Republic of China; Department of Internal Medicine, Heilongjiang Provincial Zhaoyuan People’s Hospital, Zhaoyuan, People’s Republic of China

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SUNG-TAE HONGDepartment of Parasitology and Tropical Medicine, and Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul, Republic of Korea; Heilongjiang Provincial Zhaoyuanxian Center for Disease Control and Prevention, Zhaoyuan, People’s Republic of China; Department of Internal Medicine, Heilongjiang Provincial Zhaoyuan People’s Hospital, Zhaoyuan, People’s Republic of China

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A 35-year-old Chinese man was administered praziquantel for clonorchiasis, and 30 minutes later he experienced a sudden onset of itching urticaria over his entire body with dyspnea, palpitation, and dizziness. The patient had no recent medication history except for the praziquantel. He was diagnosed as having an anaphylactic reaction with skin eruptions induced by praziquantel. His symptoms subsided after a stomach wash and the administration of anti-anaphylactic medication in emergency department of a regional hospital in the People’s Republic of China. The immediate type of hypersensitive reaction to praziquantel is plausible, and this reaction should be considered for praziquantel therapy.

Author Notes

Reprint requests: Sung-Tae Hong, Department of Parasitology and Tropical Medicine, and Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea.
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