• 1

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    Centers for Disease Control and Prevention, 2004. Two cases of hantavirus pulmonary syndrome—Randolph County, West Virginia, July 2004. Morb Mortal Wkly Rep 53 :1086–1089.

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TWO CASES OF HANTAVIRUS PULMONARY SYNDROME IN RANDOLPH COUNTY, WEST VIRGINIA: A COINCIDENCE OF TIME AND PLACE?

JULIE R. SINCLAIRCenters for Disease Control and Prevention, Atlanta, Georgia; Virginia Department of Health, Christiansburg, Virginia; West Virginia Department of Health and Human Resources, Charleston, West Virginia

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DARIN S. CARROLLCenters for Disease Control and Prevention, Atlanta, Georgia; Virginia Department of Health, Christiansburg, Virginia; West Virginia Department of Health and Human Resources, Charleston, West Virginia

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JOEL M. MONTGOMERYCenters for Disease Control and Prevention, Atlanta, Georgia; Virginia Department of Health, Christiansburg, Virginia; West Virginia Department of Health and Human Resources, Charleston, West Virginia

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BORIS PAVLINCenters for Disease Control and Prevention, Atlanta, Georgia; Virginia Department of Health, Christiansburg, Virginia; West Virginia Department of Health and Human Resources, Charleston, West Virginia

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KATHERINE MCCOMBSCenters for Disease Control and Prevention, Atlanta, Georgia; Virginia Department of Health, Christiansburg, Virginia; West Virginia Department of Health and Human Resources, Charleston, West Virginia

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JAMES N. MILLSCenters for Disease Control and Prevention, Atlanta, Georgia; Virginia Department of Health, Christiansburg, Virginia; West Virginia Department of Health and Human Resources, Charleston, West Virginia

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JAMES A. COMERCenters for Disease Control and Prevention, Atlanta, Georgia; Virginia Department of Health, Christiansburg, Virginia; West Virginia Department of Health and Human Resources, Charleston, West Virginia

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THOMAS G. KSIAZEKCenters for Disease Control and Prevention, Atlanta, Georgia; Virginia Department of Health, Christiansburg, Virginia; West Virginia Department of Health and Human Resources, Charleston, West Virginia

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PIERRE E. ROLLINCenters for Disease Control and Prevention, Atlanta, Georgia; Virginia Department of Health, Christiansburg, Virginia; West Virginia Department of Health and Human Resources, Charleston, West Virginia

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STUART T. NICHOLCenters for Disease Control and Prevention, Atlanta, Georgia; Virginia Department of Health, Christiansburg, Virginia; West Virginia Department of Health and Human Resources, Charleston, West Virginia

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ANGELA J. SANCHEZCenters for Disease Control and Prevention, Atlanta, Georgia; Virginia Department of Health, Christiansburg, Virginia; West Virginia Department of Health and Human Resources, Charleston, West Virginia

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CHRISTINA L. HUTSONCenters for Disease Control and Prevention, Atlanta, Georgia; Virginia Department of Health, Christiansburg, Virginia; West Virginia Department of Health and Human Resources, Charleston, West Virginia

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MICHAEL BELLCenters for Disease Control and Prevention, Atlanta, Georgia; Virginia Department of Health, Christiansburg, Virginia; West Virginia Department of Health and Human Resources, Charleston, West Virginia

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JANE A. ROONEYCenters for Disease Control and Prevention, Atlanta, Georgia; Virginia Department of Health, Christiansburg, Virginia; West Virginia Department of Health and Human Resources, Charleston, West Virginia

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Hantavirus pulmonary syndrome (HPS) is caused by an infection with viruses of the genus Hantavirus in the western hemisphere. Rodent hosts of hantaviruses are present throughout the United States. In July 2004, two HPS case-patients were identified in Randolph County, WV: a wildlife science graduate student working locally and a Randolph County resident. We interviewed family members and colleagues, reviewed medical records, and conducted environmental studies at likely exposure sites. Small mammals were trapped, and blood, urine, and tissue samples were submitted to the Centers for Disease Control and Prevention for laboratory analyses. These analyses confirmed that both patients were infected with Monongahela virus, a Sin Nombre hantavirus variant hosted by the Cloudland deer mouse, Peromyscus maniculatus nubiterrae. Other than one retrospectively diagnosed case in 1981, these are the first HPS cases reported in West Virginia. These cases emphasize the need to educate the public throughout the United States regarding risks and prevention measures for hantavirus infection.

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