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RefWorks
Reference Manager
BibTeX
Zotero
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-
1
Holder AA, 1994. Preventing merozoite invasion of erythrocytes. Hoffman SL, ed. Malaria Vaccine Development: A Multi-Immune Approach. Washington, DC: American Society for Microbiology Press, 77–104.
-
2
Waters AP, Thomas AW, Deans JA, Mitchell GH, Hudson DE, Miller LH, McCutchan TF, Cohen S, 1990. A merozoite receptor protein from Plasmodium knowlesi is highly conserved and distributed throughout Plasmodium. J Biol Chem 265 :17974–17979.
-
3
Hehl AB, Lekutis C, Grigg ME, Bradley PJ, Dubremetz JF, Ortega-Barria E, Boothroyd JC, 2000. Toxoplasma gondii homologue of Plasmodium apical membrane antigen 1 is involved in invasion of host cells. Infect Immun 68 :7078–7086.
-
4
Gaffar FR, Yatsuda AP, Franssen FF, de Vries E, 2004. Erythrocyte invasion by Babesia bovis merozoites is inhibited by polyclonal antisera directed against peptides derived from a homologue of Plasmodium falciparum apical membrane antigen 1. Infect Immun 72 :2947–2955.
-
5
Hodder AN, Crewther PE, Matthew ML, Reid GE, Moritz RL, Simpson RJ, Anders RF, 1996. The disulfide bond structure of Plasmodium apical membrane antigen-1. J Biol Chem 271 :29446–29452.
-
6
Pizarro JC, Vulliez-Le Normand B, Chesne-Seck ML, Collins CR, Withers-Martinez C, Hackett F, Blackman MJ, Faber BW, Remarque EJ, Kocken CH, Thomas AW, Bentley GA, 2005. Crystal structure of the malaria vaccine candidate apical membrane antigen 1. Science 308 :408–411.
-
7
Bannister LH, Hopkins JM, Dluzewski AR, Margos G, Williams IT, Blackman MJ, Kocken CH, Thomas AW, Mitchell GH, 2003. Plasmodium falciparum apical membrane antigen 1 (PfAMA-1) is translocated within micronemes along subpellicular microtubules during merozoite development. J Cell Sci 116 :3825–3834.
-
8
Peterson MG, Marshall VM, Smythe JA, Crewther PE, Lew A, Silva A, Anders RF, Kemp DJ, 1989. Integral membrane protein located in the apical complex of Plasmodium falciparum. Mol Cell Biol 9 :3151–3154.
-
9
Narum DL, Thomas AW, 1994. Differential localization of full-length and processed forms of PF83/AMA-1 an apical membrane antigen of Plasmodium falciparum merozoites. Mol Biochem Parasitol 67 :59–68.
-
10
Howell SA, Withers-Martinez C, Kocken CH, Thomas AW, Blackman MJ, 2001. Proteolytic processing and primary structure of Plasmodium falciparum apical membrane antigen-1. J Biol Chem 276 :31311–31320.
-
11
Howell SA, Well I, Fleck SL, Kettleborough C, Collins CR, Blackman MJ, 2003. A single malaria merozoite serine protease mediates shedding of multiple surface proteins by juxtamembrane cleavage. J Biol Chem 278 :23890–23898.
-
12
Triglia T, Healer J, Caruana SR, Hodder AN, Anders RF, Crabb BS, Cowman AF, 2000. Apical membrane antigen 1 plays a central role in erythrocyte invasion by Plasmodium species. Mol Microbiol 38 :706–718.
-
13
Mitchell GH, Thomas AW, Margos G, Dluzewski AR, Bannister LH, 2004. Apical membrane antigen 1, a major malaria vaccine candidate, mediates the close attachment of invasive merozoites to host red blood cells. Infect Immun 72 :154–158.
-
14
Anders RF, Crewther PE, Edwards S, Margetts M, Matthew ML, Pollock B, Pye D, 1998. Immunisation with recombinant AMA-1 protects mice against infection with Plasmodium chabaudi. Vaccine 16 :240–247.
-
15
Stowers AW, Kennedy MC, Keegan BP, Saul A, Long CA, Miller LH, 2002. Vaccination of monkeys with recombinant Plasmodium falciparum apical membrane antigen 1 confers protection against blood-stage malaria. Infect Immun 70 :6961–6967.
-
16
Udhayakumar V, Kariuki S, Kolczack M, Girma M, Roberts JM, Oloo AJ, Nahlen BL, Lal AA, 2001. Longitudinal study of natural immune responses to the Plasmodium falciparum apical membrane antigen (AMA-1) in a holoendemic region of malaria in western Kenya: Asembo Bay Cohort Project VIII. Am J Trop Med Hyg 65 :100–107.
-
17
Thomas AW, Trape JF, Rogier C, Goncalves A, Rosario VE, Narum DL, 1994. High prevalence of natural antibodies against Plasmodium falciparum 83-kilodalton apical membrane antigen (PF83/AMA-1) as detected by capture-enzyme-linked immunosorbent assay using full-length baculovirus recombinant PF83/AMA-1. Am J Trop Med Hyg 51 :730–740.
-
18
Polley SD, Mwangi T, Kocken CH, Thomas AW, Dutta S, Lanar DE, Remarque E, Ross A, Williams TN, Mwambingu G, Lowe B, Conway DJ, Marsh K, 2004. Human antibodies to recombinant protein constructs of Plasmodium falciparum apical membrane antigen 1 (AMA1) and their associations with protection from malaria. Vaccine 23 :718–728.
-
19
Scopel KK, Fontes CJ, Ferreira MU, Braga EM, 2005. Plasmodium falciparum: IgG subclass antibody response to merozoite surface protein-1 among Amazonian gold miners, in relation to infection status and disease expression. Exp Parasitol 109 :124–134.
-
20
Fontes CJ, Bathurst I, Krettli AU, 1991. Plasmodium vivax sporozoite antibodies in individuals exposed during a single malaria outbreak in a non-endemic area. Am J Trop Med Hyg 44 :28–33.
-
21
Braga EM, Fontes CJ, Krettli AU, 1998. Persistence of humoral response against sporozoite and blood-stage malaria antigens 7 years after a brief exposure to Plasmodium vivax. J Infect Dis 177 :1132–1135.
-
22
Morais CG, Soares IS, Carvalho LH, Fontes CJ, Krettli AU, Braga EM, 2005. IgG isotype to C-terminal 19 kDa of Plasmodium vivax merozoite surface protein 1 among subjects with different levels of exposure to malaria in Brazil. Parasitol Res 95 :420–426.
-
23
Rodrigues MH, Rodrigues KM, Oliveira TR, Comodo AN, Rodrigues MM, Kocken CH, Thomas AW, Soares IS, 2005. Antibody response of naturally infected individuals to recombinant Plasmodium vivax apical membrane antigen-1. Int J Parasitol 35 :185–192.
-
24
Bouharoun-Tayoun H, Oeuvray C, Lunel F, Druilhe P, 1995. Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages. J Exp Med 182 :409–418.
-
25
Bouharoun-Tayoun H, Attanath P, Sabchareon A, Chongsuphajaisiddhi T, Druilhe P, 1990. Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytes. J Exp Med 172 :1633–1641.
-
26
Bouharoun-Tayoun H, Druilhe P, 1992. Plasmodium falciparum malaria: evidence for an isotype imbalance which may be responsible for delayed acquisition of protective immunity. Infect Immun 60 :1473–1481.
-
27
Braga EM, Barros RM, Reis TA, Fontes CJ, Morais CG, Martins MS, Krettli AU, 2002. Association of the IgG response to Plasmodium falciparum merozoite protein (C-terminal 19 kD) with clinical immunity to malaria in the Brazilian Amazon region. Am J Trop Med Hyg 66 :461–466.
-
28
Ferrante A, Rzepczyc CM, 1997. Atypical IgG subclass antibody responses to Plasmodium falciparum asexual blood stage antigens. Parasitol Today 13 :145–148.
-
29
Bachmann MF, Odermatt B, Hengartner H, Zinkernagel RM, 1996. Induction of long-lived germinal centers associated with persisting antigen after viral infection. J Exp Med 183 :2259–2269.
-
30
Manz RA, Hauser AE, Hiepe F, Radbruch A, 2005. Maintenance of serum antibody levels. Annu Rev Immunol 23 :367–386.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 185 | 150 | 6 |
| Full Text Views | 304 | 4 | 0 |
| PDF Downloads | 52 | 4 | 0 |
ANTIBODIES TO PLASMODIUM VIVAX APICAL MEMBRANE ANTIGEN 1: PERSISTENCE AND CORRELATION WITH MALARIA TRANSMISSION INTENSITY
CRISTIANE G. MORAIS
CRISTIANE G. MORAIS
Departamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Departamento de Análises Clínicas e Toxicológicas, Universidade de Sao Paulo, Sao Paulo, Brazil; Universidade Federal de Mato Grosso, Cuiabá, Mato Grosso, Brazil; Centro de Pesquisas René Rachou/FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil
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IRENE S. SOARES
IRENE S. SOARES
Departamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Departamento de Análises Clínicas e Toxicológicas, Universidade de Sao Paulo, Sao Paulo, Brazil; Universidade Federal de Mato Grosso, Cuiabá, Mato Grosso, Brazil; Centro de Pesquisas René Rachou/FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil
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LUZIA H. CARVALHO
LUZIA H. CARVALHO
Departamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Departamento de Análises Clínicas e Toxicológicas, Universidade de Sao Paulo, Sao Paulo, Brazil; Universidade Federal de Mato Grosso, Cuiabá, Mato Grosso, Brazil; Centro de Pesquisas René Rachou/FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil
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COR J. F. FONTES
COR J. F. FONTES
Departamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Departamento de Análises Clínicas e Toxicológicas, Universidade de Sao Paulo, Sao Paulo, Brazil; Universidade Federal de Mato Grosso, Cuiabá, Mato Grosso, Brazil; Centro de Pesquisas René Rachou/FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil
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ANTONIANA U. KRETTLI
ANTONIANA U. KRETTLI
Departamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Departamento de Análises Clínicas e Toxicológicas, Universidade de Sao Paulo, Sao Paulo, Brazil; Universidade Federal de Mato Grosso, Cuiabá, Mato Grosso, Brazil; Centro de Pesquisas René Rachou/FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil
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ÉRIKA M. BRAGA
ÉRIKA M. BRAGA
Departamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Departamento de Análises Clínicas e Toxicológicas, Universidade de Sao Paulo, Sao Paulo, Brazil; Universidade Federal de Mato Grosso, Cuiabá, Mato Grosso, Brazil; Centro de Pesquisas René Rachou/FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil
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The antibody responses to the apical membrane antigen 1 of the Plasmodium vivax (PvAMA-1) were investigated in subjects living in areas of Brazil with different levels of malaria transmission. The prevalence and the levels of IgG to PvAMA-1 increased with the time of exposure. The frequency of a positive response and the mean IgG level were higher in areas where malaria prevalence was more intense, especially among non-infected subjects exposed to moderate transmission over a period of 20 years. The proportions and levels of IgG1and IgG3 isotypes were significantly higher among those subjects with long-term exposure. Antibodies, mainly IgG1, to PvAMA-1 persisted for seven years among subjects briefly exposed to malaria in an outbreak outside the Brazilian malaria-endemic area. These data show the highly immunogenic properties of PvAMA-1 and emphasize its possible use as a malaria vaccine candidate.
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RefWorks
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-
1
Holder AA, 1994. Preventing merozoite invasion of erythrocytes. Hoffman SL, ed. Malaria Vaccine Development: A Multi-Immune Approach. Washington, DC: American Society for Microbiology Press, 77–104.
-
2
Waters AP, Thomas AW, Deans JA, Mitchell GH, Hudson DE, Miller LH, McCutchan TF, Cohen S, 1990. A merozoite receptor protein from Plasmodium knowlesi is highly conserved and distributed throughout Plasmodium. J Biol Chem 265 :17974–17979.
-
3
Hehl AB, Lekutis C, Grigg ME, Bradley PJ, Dubremetz JF, Ortega-Barria E, Boothroyd JC, 2000. Toxoplasma gondii homologue of Plasmodium apical membrane antigen 1 is involved in invasion of host cells. Infect Immun 68 :7078–7086.
-
4
Gaffar FR, Yatsuda AP, Franssen FF, de Vries E, 2004. Erythrocyte invasion by Babesia bovis merozoites is inhibited by polyclonal antisera directed against peptides derived from a homologue of Plasmodium falciparum apical membrane antigen 1. Infect Immun 72 :2947–2955.
-
5
Hodder AN, Crewther PE, Matthew ML, Reid GE, Moritz RL, Simpson RJ, Anders RF, 1996. The disulfide bond structure of Plasmodium apical membrane antigen-1. J Biol Chem 271 :29446–29452.
-
6
Pizarro JC, Vulliez-Le Normand B, Chesne-Seck ML, Collins CR, Withers-Martinez C, Hackett F, Blackman MJ, Faber BW, Remarque EJ, Kocken CH, Thomas AW, Bentley GA, 2005. Crystal structure of the malaria vaccine candidate apical membrane antigen 1. Science 308 :408–411.
-
7
Bannister LH, Hopkins JM, Dluzewski AR, Margos G, Williams IT, Blackman MJ, Kocken CH, Thomas AW, Mitchell GH, 2003. Plasmodium falciparum apical membrane antigen 1 (PfAMA-1) is translocated within micronemes along subpellicular microtubules during merozoite development. J Cell Sci 116 :3825–3834.
-
8
Peterson MG, Marshall VM, Smythe JA, Crewther PE, Lew A, Silva A, Anders RF, Kemp DJ, 1989. Integral membrane protein located in the apical complex of Plasmodium falciparum. Mol Cell Biol 9 :3151–3154.
-
9
Narum DL, Thomas AW, 1994. Differential localization of full-length and processed forms of PF83/AMA-1 an apical membrane antigen of Plasmodium falciparum merozoites. Mol Biochem Parasitol 67 :59–68.
-
10
Howell SA, Withers-Martinez C, Kocken CH, Thomas AW, Blackman MJ, 2001. Proteolytic processing and primary structure of Plasmodium falciparum apical membrane antigen-1. J Biol Chem 276 :31311–31320.
-
11
Howell SA, Well I, Fleck SL, Kettleborough C, Collins CR, Blackman MJ, 2003. A single malaria merozoite serine protease mediates shedding of multiple surface proteins by juxtamembrane cleavage. J Biol Chem 278 :23890–23898.
-
12
Triglia T, Healer J, Caruana SR, Hodder AN, Anders RF, Crabb BS, Cowman AF, 2000. Apical membrane antigen 1 plays a central role in erythrocyte invasion by Plasmodium species. Mol Microbiol 38 :706–718.
-
13
Mitchell GH, Thomas AW, Margos G, Dluzewski AR, Bannister LH, 2004. Apical membrane antigen 1, a major malaria vaccine candidate, mediates the close attachment of invasive merozoites to host red blood cells. Infect Immun 72 :154–158.
-
14
Anders RF, Crewther PE, Edwards S, Margetts M, Matthew ML, Pollock B, Pye D, 1998. Immunisation with recombinant AMA-1 protects mice against infection with Plasmodium chabaudi. Vaccine 16 :240–247.
-
15
Stowers AW, Kennedy MC, Keegan BP, Saul A, Long CA, Miller LH, 2002. Vaccination of monkeys with recombinant Plasmodium falciparum apical membrane antigen 1 confers protection against blood-stage malaria. Infect Immun 70 :6961–6967.
-
16
Udhayakumar V, Kariuki S, Kolczack M, Girma M, Roberts JM, Oloo AJ, Nahlen BL, Lal AA, 2001. Longitudinal study of natural immune responses to the Plasmodium falciparum apical membrane antigen (AMA-1) in a holoendemic region of malaria in western Kenya: Asembo Bay Cohort Project VIII. Am J Trop Med Hyg 65 :100–107.
-
17
Thomas AW, Trape JF, Rogier C, Goncalves A, Rosario VE, Narum DL, 1994. High prevalence of natural antibodies against Plasmodium falciparum 83-kilodalton apical membrane antigen (PF83/AMA-1) as detected by capture-enzyme-linked immunosorbent assay using full-length baculovirus recombinant PF83/AMA-1. Am J Trop Med Hyg 51 :730–740.
-
18
Polley SD, Mwangi T, Kocken CH, Thomas AW, Dutta S, Lanar DE, Remarque E, Ross A, Williams TN, Mwambingu G, Lowe B, Conway DJ, Marsh K, 2004. Human antibodies to recombinant protein constructs of Plasmodium falciparum apical membrane antigen 1 (AMA1) and their associations with protection from malaria. Vaccine 23 :718–728.
-
19
Scopel KK, Fontes CJ, Ferreira MU, Braga EM, 2005. Plasmodium falciparum: IgG subclass antibody response to merozoite surface protein-1 among Amazonian gold miners, in relation to infection status and disease expression. Exp Parasitol 109 :124–134.
-
20
Fontes CJ, Bathurst I, Krettli AU, 1991. Plasmodium vivax sporozoite antibodies in individuals exposed during a single malaria outbreak in a non-endemic area. Am J Trop Med Hyg 44 :28–33.
-
21
Braga EM, Fontes CJ, Krettli AU, 1998. Persistence of humoral response against sporozoite and blood-stage malaria antigens 7 years after a brief exposure to Plasmodium vivax. J Infect Dis 177 :1132–1135.
-
22
Morais CG, Soares IS, Carvalho LH, Fontes CJ, Krettli AU, Braga EM, 2005. IgG isotype to C-terminal 19 kDa of Plasmodium vivax merozoite surface protein 1 among subjects with different levels of exposure to malaria in Brazil. Parasitol Res 95 :420–426.
-
23
Rodrigues MH, Rodrigues KM, Oliveira TR, Comodo AN, Rodrigues MM, Kocken CH, Thomas AW, Soares IS, 2005. Antibody response of naturally infected individuals to recombinant Plasmodium vivax apical membrane antigen-1. Int J Parasitol 35 :185–192.
-
24
Bouharoun-Tayoun H, Oeuvray C, Lunel F, Druilhe P, 1995. Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages. J Exp Med 182 :409–418.
-
25
Bouharoun-Tayoun H, Attanath P, Sabchareon A, Chongsuphajaisiddhi T, Druilhe P, 1990. Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytes. J Exp Med 172 :1633–1641.
-
26
Bouharoun-Tayoun H, Druilhe P, 1992. Plasmodium falciparum malaria: evidence for an isotype imbalance which may be responsible for delayed acquisition of protective immunity. Infect Immun 60 :1473–1481.
-
27
Braga EM, Barros RM, Reis TA, Fontes CJ, Morais CG, Martins MS, Krettli AU, 2002. Association of the IgG response to Plasmodium falciparum merozoite protein (C-terminal 19 kD) with clinical immunity to malaria in the Brazilian Amazon region. Am J Trop Med Hyg 66 :461–466.
-
28
Ferrante A, Rzepczyc CM, 1997. Atypical IgG subclass antibody responses to Plasmodium falciparum asexual blood stage antigens. Parasitol Today 13 :145–148.
-
29
Bachmann MF, Odermatt B, Hengartner H, Zinkernagel RM, 1996. Induction of long-lived germinal centers associated with persisting antigen after viral infection. J Exp Med 183 :2259–2269.
-
30
Manz RA, Hauser AE, Hiepe F, Radbruch A, 2005. Maintenance of serum antibody levels. Annu Rev Immunol 23 :367–386.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 185 | 150 | 6 |
| Full Text Views | 304 | 4 | 0 |
| PDF Downloads | 52 | 4 | 0 |