ENTEROPATHOGENIC ESCHERICHIA COLI O157 IN BANGUI AND N’GOILA, CENTRAL AFRICAN REPUBLIC: A BRIEF REPORT

DINH THI N. TUYET Institut Pasteur de Bangui, Bangui, Central African Republic; Hôpital de l’Amitié, Service de Gastro-entérologie, Bangui, Central African Republic; Agence Nationale de Développement et de l’Elevage, Bangui, Central African Republic; Institut Pasteur d’Ho Chi Minh Ville, Ho Chi Minh Ville, Vietnam; Laboratoire National de Biologie Clinique et Santé Publique, Bangui, Central African Republic.

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SIMON YASSIBANDA Institut Pasteur de Bangui, Bangui, Central African Republic; Hôpital de l’Amitié, Service de Gastro-entérologie, Bangui, Central African Republic; Agence Nationale de Développement et de l’Elevage, Bangui, Central African Republic; Institut Pasteur d’Ho Chi Minh Ville, Ho Chi Minh Ville, Vietnam; Laboratoire National de Biologie Clinique et Santé Publique, Bangui, Central African Republic.

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PHUONG L. NGUYEN THI Institut Pasteur de Bangui, Bangui, Central African Republic; Hôpital de l’Amitié, Service de Gastro-entérologie, Bangui, Central African Republic; Agence Nationale de Développement et de l’Elevage, Bangui, Central African Republic; Institut Pasteur d’Ho Chi Minh Ville, Ho Chi Minh Ville, Vietnam; Laboratoire National de Biologie Clinique et Santé Publique, Bangui, Central African Republic.

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MARCEL R. KOYENEDE Institut Pasteur de Bangui, Bangui, Central African Republic; Hôpital de l’Amitié, Service de Gastro-entérologie, Bangui, Central African Republic; Agence Nationale de Développement et de l’Elevage, Bangui, Central African Republic; Institut Pasteur d’Ho Chi Minh Ville, Ho Chi Minh Ville, Vietnam; Laboratoire National de Biologie Clinique et Santé Publique, Bangui, Central African Republic.

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MALIKA GOUALI Institut Pasteur de Bangui, Bangui, Central African Republic; Hôpital de l’Amitié, Service de Gastro-entérologie, Bangui, Central African Republic; Agence Nationale de Développement et de l’Elevage, Bangui, Central African Republic; Institut Pasteur d’Ho Chi Minh Ville, Ho Chi Minh Ville, Vietnam; Laboratoire National de Biologie Clinique et Santé Publique, Bangui, Central African Republic.

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CLAUDINE BÉKONDI Institut Pasteur de Bangui, Bangui, Central African Republic; Hôpital de l’Amitié, Service de Gastro-entérologie, Bangui, Central African Republic; Agence Nationale de Développement et de l’Elevage, Bangui, Central African Republic; Institut Pasteur d’Ho Chi Minh Ville, Ho Chi Minh Ville, Vietnam; Laboratoire National de Biologie Clinique et Santé Publique, Bangui, Central African Republic.

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JEAN MAZZI Institut Pasteur de Bangui, Bangui, Central African Republic; Hôpital de l’Amitié, Service de Gastro-entérologie, Bangui, Central African Republic; Agence Nationale de Développement et de l’Elevage, Bangui, Central African Republic; Institut Pasteur d’Ho Chi Minh Ville, Ho Chi Minh Ville, Vietnam; Laboratoire National de Biologie Clinique et Santé Publique, Bangui, Central African Republic.

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YVES GERMANI Institut Pasteur de Bangui, Bangui, Central African Republic; Hôpital de l’Amitié, Service de Gastro-entérologie, Bangui, Central African Republic; Agence Nationale de Développement et de l’Elevage, Bangui, Central African Republic; Institut Pasteur d’Ho Chi Minh Ville, Ho Chi Minh Ville, Vietnam; Laboratoire National de Biologie Clinique et Santé Publique, Bangui, Central African Republic.

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Escherichia coli O157:H7 producing Shiga like toxins is a food-borne pathogen frequently isolated in Bangui from patients with hemorrhagic colitis (HC). This survey provides comprehensive data on the high prevalence of E. coli O157:H7 infection in Bangui: carriage of E. coli O157:H7 by zebu (Bos indicus) and fish, contamination of the fields at N’Goila where the butchers kill the zebus, and contamination of the field surface water along the M’Poko River upstream of the Oubangui River where fish are caught, appear to be important contributory factors. We also describe novel strains of serogroup O157:NM isolated from zebu and from fish; a variety of assays indicate that these strains belong to the enteropathogenic pathotype, though they lack certain genetic elements thought to be diagnostic for this pathotype.

Author Notes

Reprint requests: Dr. Yves Germani, Institut Pasteur, Unité Pathogénie Microbienne Moléculaire / Réseau International des Instituts Pasteur, 25 – 28 rue du Dr Roux, 75724 Paris Cedex 15, Telephone: 33 (0)1 44 38 95 76, Fax: 33 (0)1 45 68 89 53. E-mail: ygermani@pasteur.fr.
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