Author:
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1
Menendez C, Fleming AF, Alonso PL, 2000. Malaria-related anaemia. Parasitol Today 16 :469–476.
-
2
Nussenblatt V, Semba RD, 2002. Micronutrient malnutrition and the pathogenesis of malarial anemia. Acta Trop 82 :321–337.
-
3
Nagel RL, 2002. Malarial anemia. Hemoglobin 26 :329–343.
-
4
Ekvall H, 2003. Malaria and anemia. Curr Opin Hematol 10 :108–114.
-
5
Steketee RW, 2003. Pregnancy, nutrition and parasitic diseases. J Nutr 133 :1661S–1667S.
-
6
Crawley J, 2004. Reducing the burden of anemia in infants and young children in malaria-endemic countries of Africa: from evidence to action. Am J Trop Med Hyg 71 (Suppl 2):25–34.
-
7
Prinsen Geerligs PD, Brabin BJ, Eggelte TA, 2003. Analysis of the effects of malaria chemoprophylaxis in children on haematological responses, morbidity and mortality. Bull World Health Organ 81 :205–216.
-
8
Korenromp EL, Armstrong-Schellenberg JR, Williams BG, Nahlen BL, Snow RW, 2004. Impact of malaria control on childhood anaemia in Africa–a quantitative review. Trop Med Int Health 9 :1050–1065.
-
9
Curtis C, Maxwell C, Lemnge M, Kilama WL, Steketee RW, Hawley WA, Bergevin Y, Campbell CC, Sachs J, Teklehaimanot A, Ochola S, Guyatt H, Snow RW, 2003. Scaling-up coverage with insecticide-treated nets against malaria in Africa: who should pay? Lancet Infect Dis 3 :304–307.
-
10
Lengeler C, 2004. Insecticide-treated bed nets and curtains for preventing malaria. Cochrane Database Syst Rev: CD000363.
-
11
Schellenberg D, Menendez C, Kahigwa E, Aponte J, Vidal J, Tanner M, Mshinda H, Alonso PL, 2001. Intermittent treatment for malaria and anaemia control at time of routine vaccinations in Tanzanian infants: a randomised, placebo-controlled trial. Lancet 357 :1471–1477.
-
12
Alonso PL, Sacarlal J, Aponte J, Leach A, Macete E, Milman J, Mandomando I, Spiessens B, Guinovart C, Espasa M, Bassat Q, Aide P, Ofori-Anyinam O, Navia MM, Corachan S, Ceuppens M, Dubois MC, Demoitie MA, Dubovsky F, Menendez C, Tornieporth N, Ballou WR, Thompson R, Cohen J, 2004. Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial. Lancet 364 :1411–1420.
-
13
Drakeley C, Carneiro I, Reyburn H, Malima R, Lusingu J, Cox J, Theander TG, Nkya WM, Lemnge MM, Riley E, 2005. Altitude dependent and altitude independent variations in Plasmodium falciparum prevalence in northeastern Tanzania. J Infect Dis 191 :1589–1598.
-
14
Enevold A, Vestergard LS, Lusingu J, Drakeley CJ, Lemnge MM, Theander TG, Bygbjerg IC, Alifrangis M, 2005. Rapid screening for glucose-6-phosphate dehydrogenase deficiency and haemoglobin polymorphisms in Africa by a simple high-throughput SSOP-ELISA method. Malar J 4 :61.
-
15
Drakeley C, Corran P, Coleman P, Tongren J, McDonald SLR, Carneiro I, Malima R, Lusingu J, Manjurano A, Nkya W, Lemge M, Cox J, Reyburn H, Riley E, 2005. Estimating medium- and long-term trends in malaria transmission by using serological markers of malaria exposure. Proc Natl Acad Sci U S A 102 :5108–5113.
-
16
Winbugs, 2003. Cambridge, United Kingdom: Medical Research Council Biostatistics Unit.
-
17
Spiegelhalter DJ, Best N, Carlin BP, van der Linde A, 2002. Bayesian measures of model complexity and fit (with discussion). J R Stat Soc B 64 :583–640.
-
18
Stoltzfus RJ, Chwaya HM, Montresor A, Albonico M, Savioli L, Tielsch JM, 2000. Malaria, hookworms and recent fever are related to anemia and iron status indicators in 0- to 5-y old Zanzibari children and these relationships change with age. J Nutr 130 :1724–1733.
-
19
Jakeman GN, Saul A, Hogarth WL, Collins WE, 1999. Anaemia of acute malaria infections in non-immune patients primarily results from destruction of uninfected erythrocytes. Parasitology 119 :127–133.
-
20
Phillips RE, Looareesuwan S, Warrell DA, Lee SH, Karbwang J, Warrell MJ, White N, Swasdichai C, Weatherall DJ, 1986. The importance of anaemia in cerebral and uncomplicated falciparum malaria: role of complications, dyserythropoiesis and iron sequestration. QJM 58 :305–323.
-
21
Weidanz WP, Long CA, 1988. The role of T cells in immunity to malaria. Perlmann P, Wigzell H, eds. Progress in Allergy. Volume 41. Malaria Immunology. Basel: Karger, 215–252.
-
22
McDevitt M, Xie J, Gordeuk V, Bucala R, 2005. The anemia of malaria infection: role of inflammatory cytokines. Curr Hematol Rep 3 :97–106.
-
23
Kitua A, Smith TA, Alonso PL, Urassa H, Masanja H, Kimario J, Tanner M, 1997. The role of low level Plasmodium falciparum parasitaemia in anaemia among infants living in an area of intense and perennial transmission. Trop Med Int Health 2 :325–333.
-
24
Murphy SC, Breman JG, 2001. Gaps in the childhood malaria burden in Africa: cerebral malaria, neurological sequelae, anemia, respiratory distress, hypoglycaemia, and complications of pregnancy. Am J Trop Med Hyg 64 :57–67.
-
25
Snow R, Craig M, Newton C, Steketee RW, 2003. The Public Health Burden of Plasmodium falciparum Malaria in Africa: Deriving the Numbers. Bethesda, MD: Fogarty International Center, National Institutes of Health.
-
26
Carneiro IA, Roca-Feltrer A, Schellenberg JR, 2005. Estimates of the Burden of Malaria Morbidity in Africa in Children under the Age of Five Years. Geneva: World Health Organization. Child Health Epidemiology Reference Group Working Paper. Available at: http://www.who.int/child-adolescent-heath/New_Publications/CHILD_HEALTH/EPI/CHERG_Malaria_Morbidity.pdf.
-
27
Newman RD, Hailemariam A, Jimma D, Degifie A, Kebede D, Rietveld AE, Nahlen BL, Barnwell JW, Steketee RW, Parise ME, 2003. Burden of malaria during pregnancy in areas of stable and unstable transmission in Ethiopia during a nonepidemic year. J Infect Dis 187 :1765–1772.
-
28
Rogerson SJ, Pollina E, Getachew A, Tadesse E, Lema VM, Molyneux ME, 2003. Placental monocyte infiltrates in response to Plasmodium falciparum malaria infection and their association with adverse pregnancy outcomes. Am J Trop Med Hyg 68 :115–119.
-
29
Lusingu JP, Jones C, Akida J, Savaeli ZX, Kitua AY, Lemnge MM, Theander TG, 2004. Malaria morbidity and immunity among residents of villages with different Plasmodium falciparum transmission intensity in North-Eastern Tanzania. Malar J 3 :26.
-
30
Reyburn H, Mbatia R, Drakeley C, Bruce J, Carneiro I, Oloni R, Cox J, Nkya WM, Lemnge M, Greenwood BM, Riley EM, 2005. Association of transmission intensity and age with clinical manifestations and case-fatality of severe Plasmodium falciparum malaria. JAMA 293 :1461–1470.
-
31
Brabin BJ, Premji Z, Verhoeff F, 2001. An analysis of anemia and child mortality. J Nutr 131 :636S–645S.
-
32
World Health Organization, 2001. Iron Deficiency Anaemia: Assessment, Prevention and Control. A Guide for Programme Managers. Geneva, World Health Organization.
-
33
Grantham-McGregor S, Ani C, 2001. A review of studies on the effect of iron deficiency on cognitive development in children. J Nutr 131 :649S–666S.
-
34
Verhoef H, West CE, Veenemans J, Beguin Y, Kok FJ, 2002. Stunting may determine the severity of malaria-associated anemia in African children. Pediatrics 110 :e48.
-
35
Malaney P, Spielman A, Sachs J, 2004. The malaria gap. Am J Trop Med Hyg 71 (Suppl 2):141–146.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 2363 | 2217 | 136 |
| Full Text Views | 343 | 13 | 2 |
| PDF Downloads | 82 | 11 | 0 |
MODELING THE RELATIONSHIP BETWEEN THE POPULATION PREVALENCE OF PLASMODIUM FALCIPARUM MALARIA AND ANEMIA
ILONA A. CARNEIRO
ILONA A. CARNEIRO
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom; Swiss Tropical Institute, Basel, Switzerland; National Institute for Medical Research, Amani Medical Research Centre, Amani, Tanzania; Centre for Medical Parasitology, University of Copenhagen, Copenhagen, Denmark; Joint Malaria Programme, Moshi, Tanzania
Search for other papers by ILONA A. CARNEIRO in
Current site
Google Scholar
PubMed
Search for other papers by ILONA A. CARNEIRO in
Current site
Google Scholar
PubMed
THOMAS SMITH
THOMAS SMITH
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom; Swiss Tropical Institute, Basel, Switzerland; National Institute for Medical Research, Amani Medical Research Centre, Amani, Tanzania; Centre for Medical Parasitology, University of Copenhagen, Copenhagen, Denmark; Joint Malaria Programme, Moshi, Tanzania
Search for other papers by THOMAS SMITH in
Current site
Google Scholar
PubMed
Search for other papers by THOMAS SMITH in
Current site
Google Scholar
PubMed
JOHN P. A. LUSINGU
JOHN P. A. LUSINGU
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom; Swiss Tropical Institute, Basel, Switzerland; National Institute for Medical Research, Amani Medical Research Centre, Amani, Tanzania; Centre for Medical Parasitology, University of Copenhagen, Copenhagen, Denmark; Joint Malaria Programme, Moshi, Tanzania
Search for other papers by JOHN P. A. LUSINGU in
Current site
Google Scholar
PubMed
Search for other papers by JOHN P. A. LUSINGU in
Current site
Google Scholar
PubMed
ROBERT MALIMA
ROBERT MALIMA
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom; Swiss Tropical Institute, Basel, Switzerland; National Institute for Medical Research, Amani Medical Research Centre, Amani, Tanzania; Centre for Medical Parasitology, University of Copenhagen, Copenhagen, Denmark; Joint Malaria Programme, Moshi, Tanzania
Search for other papers by ROBERT MALIMA in
Current site
Google Scholar
PubMed
Search for other papers by ROBERT MALIMA in
Current site
Google Scholar
PubMed
JÜRG UTZINGER
JÜRG UTZINGER
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom; Swiss Tropical Institute, Basel, Switzerland; National Institute for Medical Research, Amani Medical Research Centre, Amani, Tanzania; Centre for Medical Parasitology, University of Copenhagen, Copenhagen, Denmark; Joint Malaria Programme, Moshi, Tanzania
Search for other papers by JÜRG UTZINGER in
Current site
Google Scholar
PubMed
Search for other papers by JÜRG UTZINGER in
Current site
Google Scholar
PubMed
CHRIS J. DRAKELEY
CHRIS J. DRAKELEY
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom; Swiss Tropical Institute, Basel, Switzerland; National Institute for Medical Research, Amani Medical Research Centre, Amani, Tanzania; Centre for Medical Parasitology, University of Copenhagen, Copenhagen, Denmark; Joint Malaria Programme, Moshi, Tanzania
Search for other papers by CHRIS J. DRAKELEY in
Current site
Google Scholar
PubMed
Search for other papers by CHRIS J. DRAKELEY in
Current site
Google Scholar
PubMed
More than half of all young children and pregnant women are affected by anemia. Although its etiology is multi-factorial, malaria is likely to be a major contributor to chronic anemia in endemic areas. Recent reviews have examined the effect of community-based malaria control interventions on anemia. We analyze how the prevalence of anemia depends on that of Plasmodium falciparum malaria by developing models of the excess risk of anemia caused by malaria at a population level in 24 villages in northeastern Tanzania. In that setting, we estimated that the prevalence of a hemoglobin level < 8 g/dL attributable to malaria was 4.6% in infants, 4.1% in children one year of age, 2.7% in children two years of age, and 3.3% in women of childbearing age. Successful validation of our models in other malaria-endemic settings would enable their use for predicting the impact of malaria control interventions on anemia, and for long-term monitoring and surveillance of malaria.
Author Notes
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1
Menendez C, Fleming AF, Alonso PL, 2000. Malaria-related anaemia. Parasitol Today 16 :469–476.
-
2
Nussenblatt V, Semba RD, 2002. Micronutrient malnutrition and the pathogenesis of malarial anemia. Acta Trop 82 :321–337.
-
3
Nagel RL, 2002. Malarial anemia. Hemoglobin 26 :329–343.
-
4
Ekvall H, 2003. Malaria and anemia. Curr Opin Hematol 10 :108–114.
-
5
Steketee RW, 2003. Pregnancy, nutrition and parasitic diseases. J Nutr 133 :1661S–1667S.
-
6
Crawley J, 2004. Reducing the burden of anemia in infants and young children in malaria-endemic countries of Africa: from evidence to action. Am J Trop Med Hyg 71 (Suppl 2):25–34.
-
7
Prinsen Geerligs PD, Brabin BJ, Eggelte TA, 2003. Analysis of the effects of malaria chemoprophylaxis in children on haematological responses, morbidity and mortality. Bull World Health Organ 81 :205–216.
-
8
Korenromp EL, Armstrong-Schellenberg JR, Williams BG, Nahlen BL, Snow RW, 2004. Impact of malaria control on childhood anaemia in Africa–a quantitative review. Trop Med Int Health 9 :1050–1065.
-
9
Curtis C, Maxwell C, Lemnge M, Kilama WL, Steketee RW, Hawley WA, Bergevin Y, Campbell CC, Sachs J, Teklehaimanot A, Ochola S, Guyatt H, Snow RW, 2003. Scaling-up coverage with insecticide-treated nets against malaria in Africa: who should pay? Lancet Infect Dis 3 :304–307.
-
10
Lengeler C, 2004. Insecticide-treated bed nets and curtains for preventing malaria. Cochrane Database Syst Rev: CD000363.
-
11
Schellenberg D, Menendez C, Kahigwa E, Aponte J, Vidal J, Tanner M, Mshinda H, Alonso PL, 2001. Intermittent treatment for malaria and anaemia control at time of routine vaccinations in Tanzanian infants: a randomised, placebo-controlled trial. Lancet 357 :1471–1477.
-
12
Alonso PL, Sacarlal J, Aponte J, Leach A, Macete E, Milman J, Mandomando I, Spiessens B, Guinovart C, Espasa M, Bassat Q, Aide P, Ofori-Anyinam O, Navia MM, Corachan S, Ceuppens M, Dubois MC, Demoitie MA, Dubovsky F, Menendez C, Tornieporth N, Ballou WR, Thompson R, Cohen J, 2004. Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial. Lancet 364 :1411–1420.
-
13
Drakeley C, Carneiro I, Reyburn H, Malima R, Lusingu J, Cox J, Theander TG, Nkya WM, Lemnge MM, Riley E, 2005. Altitude dependent and altitude independent variations in Plasmodium falciparum prevalence in northeastern Tanzania. J Infect Dis 191 :1589–1598.
-
14
Enevold A, Vestergard LS, Lusingu J, Drakeley CJ, Lemnge MM, Theander TG, Bygbjerg IC, Alifrangis M, 2005. Rapid screening for glucose-6-phosphate dehydrogenase deficiency and haemoglobin polymorphisms in Africa by a simple high-throughput SSOP-ELISA method. Malar J 4 :61.
-
15
Drakeley C, Corran P, Coleman P, Tongren J, McDonald SLR, Carneiro I, Malima R, Lusingu J, Manjurano A, Nkya W, Lemge M, Cox J, Reyburn H, Riley E, 2005. Estimating medium- and long-term trends in malaria transmission by using serological markers of malaria exposure. Proc Natl Acad Sci U S A 102 :5108–5113.
-
16
Winbugs, 2003. Cambridge, United Kingdom: Medical Research Council Biostatistics Unit.
-
17
Spiegelhalter DJ, Best N, Carlin BP, van der Linde A, 2002. Bayesian measures of model complexity and fit (with discussion). J R Stat Soc B 64 :583–640.
-
18
Stoltzfus RJ, Chwaya HM, Montresor A, Albonico M, Savioli L, Tielsch JM, 2000. Malaria, hookworms and recent fever are related to anemia and iron status indicators in 0- to 5-y old Zanzibari children and these relationships change with age. J Nutr 130 :1724–1733.
-
19
Jakeman GN, Saul A, Hogarth WL, Collins WE, 1999. Anaemia of acute malaria infections in non-immune patients primarily results from destruction of uninfected erythrocytes. Parasitology 119 :127–133.
-
20
Phillips RE, Looareesuwan S, Warrell DA, Lee SH, Karbwang J, Warrell MJ, White N, Swasdichai C, Weatherall DJ, 1986. The importance of anaemia in cerebral and uncomplicated falciparum malaria: role of complications, dyserythropoiesis and iron sequestration. QJM 58 :305–323.
-
21
Weidanz WP, Long CA, 1988. The role of T cells in immunity to malaria. Perlmann P, Wigzell H, eds. Progress in Allergy. Volume 41. Malaria Immunology. Basel: Karger, 215–252.
-
22
McDevitt M, Xie J, Gordeuk V, Bucala R, 2005. The anemia of malaria infection: role of inflammatory cytokines. Curr Hematol Rep 3 :97–106.
-
23
Kitua A, Smith TA, Alonso PL, Urassa H, Masanja H, Kimario J, Tanner M, 1997. The role of low level Plasmodium falciparum parasitaemia in anaemia among infants living in an area of intense and perennial transmission. Trop Med Int Health 2 :325–333.
-
24
Murphy SC, Breman JG, 2001. Gaps in the childhood malaria burden in Africa: cerebral malaria, neurological sequelae, anemia, respiratory distress, hypoglycaemia, and complications of pregnancy. Am J Trop Med Hyg 64 :57–67.
-
25
Snow R, Craig M, Newton C, Steketee RW, 2003. The Public Health Burden of Plasmodium falciparum Malaria in Africa: Deriving the Numbers. Bethesda, MD: Fogarty International Center, National Institutes of Health.
-
26
Carneiro IA, Roca-Feltrer A, Schellenberg JR, 2005. Estimates of the Burden of Malaria Morbidity in Africa in Children under the Age of Five Years. Geneva: World Health Organization. Child Health Epidemiology Reference Group Working Paper. Available at: http://www.who.int/child-adolescent-heath/New_Publications/CHILD_HEALTH/EPI/CHERG_Malaria_Morbidity.pdf.
-
27
Newman RD, Hailemariam A, Jimma D, Degifie A, Kebede D, Rietveld AE, Nahlen BL, Barnwell JW, Steketee RW, Parise ME, 2003. Burden of malaria during pregnancy in areas of stable and unstable transmission in Ethiopia during a nonepidemic year. J Infect Dis 187 :1765–1772.
-
28
Rogerson SJ, Pollina E, Getachew A, Tadesse E, Lema VM, Molyneux ME, 2003. Placental monocyte infiltrates in response to Plasmodium falciparum malaria infection and their association with adverse pregnancy outcomes. Am J Trop Med Hyg 68 :115–119.
-
29
Lusingu JP, Jones C, Akida J, Savaeli ZX, Kitua AY, Lemnge MM, Theander TG, 2004. Malaria morbidity and immunity among residents of villages with different Plasmodium falciparum transmission intensity in North-Eastern Tanzania. Malar J 3 :26.
-
30
Reyburn H, Mbatia R, Drakeley C, Bruce J, Carneiro I, Oloni R, Cox J, Nkya WM, Lemnge M, Greenwood BM, Riley EM, 2005. Association of transmission intensity and age with clinical manifestations and case-fatality of severe Plasmodium falciparum malaria. JAMA 293 :1461–1470.
-
31
Brabin BJ, Premji Z, Verhoeff F, 2001. An analysis of anemia and child mortality. J Nutr 131 :636S–645S.
-
32
World Health Organization, 2001. Iron Deficiency Anaemia: Assessment, Prevention and Control. A Guide for Programme Managers. Geneva, World Health Organization.
-
33
Grantham-McGregor S, Ani C, 2001. A review of studies on the effect of iron deficiency on cognitive development in children. J Nutr 131 :649S–666S.
-
34
Verhoef H, West CE, Veenemans J, Beguin Y, Kok FJ, 2002. Stunting may determine the severity of malaria-associated anemia in African children. Pediatrics 110 :e48.
-
35
Malaney P, Spielman A, Sachs J, 2004. The malaria gap. Am J Trop Med Hyg 71 (Suppl 2):141–146.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 2363 | 2217 | 136 |
| Full Text Views | 343 | 13 | 2 |
| PDF Downloads | 82 | 11 | 0 |