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1
Andrade-Narvaez FJ, Vargas-Gonzalez A, Canto-Lara SB, Damian-Centeno AG, 2001. Clinical picture of cutaneous leishmaniases due to Leishmania (Leishmania) mexicana in the Yucatan peninsula, Mexico. Mem Inst Oswaldo Cruz 96 :163–167.
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2
Vargas-Gonzalez A, Canto-Lara SB, Damian-Centeno AG, Andrade-Narvaez FJ, 1999. Response of cutaneous leishmaniasis (chiclero’s ulcer) to treatment with meglumine antimoniate in southeast Mexico. Am J Trop Med Hyg 61 :960–963.
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3
Edrissian GH, Mohammadi M, Kanani A, Afshar A, Hafezi R, Ghorbani M, Gharagozloo AR, 1990. Bacterial infections in suspected cutaneous leishmaniasis lesions. Bull World Health Organ 68 :473–477.
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4
Vera LA, Santos JB, Macedo VO, de Magalhaes AV, Ciuffo IA, Santos CG, 2001. Evaluation of secondary bacterial infection’s influence on the course of cutaneous leishmaniasis in Corte de Pedra. Bahia. Rev Soc Bras Med Trop 34 :233–237.
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5
O’Meara SM, Cullum NA, Majid M, Sheldon TA, 2001. Systematic review of antimicrobial agents used for chronic wounds. Br J Surg 88 :4–21.
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6
Margulis A, Bauer BS, Alizadeh K, 2003. Ear reconstruction after auricular chondritis secondary to ear piercing. Plast Reconstr Surg 111 :891–897.
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7
Mills DC II, Roberts LW, Mason AD Jr, McManus WF, Pruitt BA Jr, 1988. Suppurative chondritis: its incidence, prevention, and treatment in burn patients. Plast Reconstr Surg 82 :267–276.
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8
Bentrem DJ, Bill TJ, Himel HN, Edlich RF, 1996. Chondritis of the ear: a late sequela of deep partial thickness burns of the face. J Emerg Med 14 :469–471.
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9
More DR, Seidel JS, Bryan PA, 1999. Ear-piercing techniques as a cause of auricular chondritis. Pediatr Emerg Care 15 :189–192.
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10
Doroghazi RM, Nadol JB Jr, Hyslop NE Jr, Baker AS, Axelrod L, 1981. Invasive external otitis. Report of 21 cases and review of the literature. Am J Med 71 :603–614.
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11
Keene WE, Markum AC, Samadpour M, 2004. Outbreak of Pseudomonas aeruginosa infections caused by commercial piercing of upper ear cartilage. JAMA 291 :981–985.
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12
Caksen H, Odabas D, 2002. Perforation of the nasal septum and palatum durum in a severely malnourished infant. Pediatr Dermatol 19 :89–90.
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13
Marsden PD, 1986. Mucosal leishmaniasis (“espundia” Escomel, 1911). Trans R Soc Trop Med Hyg 80 :859–876.
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PSEUDOMONAS AERUGINOSA OTOCHONDRITIS COMPLICATING LOCALIZED CUTANEOUS LEISHMANIASIS: PREVENTION OF MUTILATION BY EARLY ANTIBIOTIC THERAPY
DIANE VAN DER VLIET
DIANE VAN DER VLIET
Institut Pasteur Medical Center, Paris, France, Department of Pathology, Dermatology Department, and Infectious Diseases Department, Necker Hospital, Assistance-Publique, Hôpitaux de Paris, Paris, France
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ANNE-SOPHIE LE GUERN
ANNE-SOPHIE LE GUERN
Institut Pasteur Medical Center, Paris, France, Department of Pathology, Dermatology Department, and Infectious Diseases Department, Necker Hospital, Assistance-Publique, Hôpitaux de Paris, Paris, France
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SYLVIE FREITAG
SYLVIE FREITAG
Institut Pasteur Medical Center, Paris, France, Department of Pathology, Dermatology Department, and Infectious Diseases Department, Necker Hospital, Assistance-Publique, Hôpitaux de Paris, Paris, France
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NICOLAS GOUNOD
NICOLAS GOUNOD
Institut Pasteur Medical Center, Paris, France, Department of Pathology, Dermatology Department, and Infectious Diseases Department, Necker Hospital, Assistance-Publique, Hôpitaux de Paris, Paris, France
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AUDREY THERBY
AUDREY THERBY
Institut Pasteur Medical Center, Paris, France, Department of Pathology, Dermatology Department, and Infectious Diseases Department, Necker Hospital, Assistance-Publique, Hôpitaux de Paris, Paris, France
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HERVE DARIE
HERVE DARIE
Institut Pasteur Medical Center, Paris, France, Department of Pathology, Dermatology Department, and Infectious Diseases Department, Necker Hospital, Assistance-Publique, Hôpitaux de Paris, Paris, France
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PIERRE A. BUFFET
PIERRE A. BUFFET
Institut Pasteur Medical Center, Paris, France, Department of Pathology, Dermatology Department, and Infectious Diseases Department, Necker Hospital, Assistance-Publique, Hôpitaux de Paris, Paris, France
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A patient with an ulcerated cutaneous leishmaniasis of the pinna had suppurative otochondritis after a first unsuccessful course of treatment with meglumine antimoniate. Although the Leishmania ulceration healed after a second course of meglumine antimoniate, and despite three oral dicloxacillin or pristinamycin courses, the otochondritis extended and an abscess developed. Pus from the abscess revealed a pure culture of Pseudomonas aeruginosa. Five days of oral ciprofloxacin plus rifampin led to a marked improvement. The P. aeruginosa isolate was sensitive to ciprofloxacin but fully resistant to rifampin. Healing with minimal mutilation was obtained at the end of a six-week course of multiple antibiotic therapy. Pseudomonas aeruginosa otochondritis was a co-factor of cartilage mutilation in this patient. Thus, infection with P. aeruginosa should be promptly treated when present in tender cutaneous or mucosal leishmaniasis lesions near cartilaginous areas.
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-
1
Andrade-Narvaez FJ, Vargas-Gonzalez A, Canto-Lara SB, Damian-Centeno AG, 2001. Clinical picture of cutaneous leishmaniases due to Leishmania (Leishmania) mexicana in the Yucatan peninsula, Mexico. Mem Inst Oswaldo Cruz 96 :163–167.
-
2
Vargas-Gonzalez A, Canto-Lara SB, Damian-Centeno AG, Andrade-Narvaez FJ, 1999. Response of cutaneous leishmaniasis (chiclero’s ulcer) to treatment with meglumine antimoniate in southeast Mexico. Am J Trop Med Hyg 61 :960–963.
-
3
Edrissian GH, Mohammadi M, Kanani A, Afshar A, Hafezi R, Ghorbani M, Gharagozloo AR, 1990. Bacterial infections in suspected cutaneous leishmaniasis lesions. Bull World Health Organ 68 :473–477.
-
4
Vera LA, Santos JB, Macedo VO, de Magalhaes AV, Ciuffo IA, Santos CG, 2001. Evaluation of secondary bacterial infection’s influence on the course of cutaneous leishmaniasis in Corte de Pedra. Bahia. Rev Soc Bras Med Trop 34 :233–237.
-
5
O’Meara SM, Cullum NA, Majid M, Sheldon TA, 2001. Systematic review of antimicrobial agents used for chronic wounds. Br J Surg 88 :4–21.
-
6
Margulis A, Bauer BS, Alizadeh K, 2003. Ear reconstruction after auricular chondritis secondary to ear piercing. Plast Reconstr Surg 111 :891–897.
-
7
Mills DC II, Roberts LW, Mason AD Jr, McManus WF, Pruitt BA Jr, 1988. Suppurative chondritis: its incidence, prevention, and treatment in burn patients. Plast Reconstr Surg 82 :267–276.
-
8
Bentrem DJ, Bill TJ, Himel HN, Edlich RF, 1996. Chondritis of the ear: a late sequela of deep partial thickness burns of the face. J Emerg Med 14 :469–471.
-
9
More DR, Seidel JS, Bryan PA, 1999. Ear-piercing techniques as a cause of auricular chondritis. Pediatr Emerg Care 15 :189–192.
-
10
Doroghazi RM, Nadol JB Jr, Hyslop NE Jr, Baker AS, Axelrod L, 1981. Invasive external otitis. Report of 21 cases and review of the literature. Am J Med 71 :603–614.
-
11
Keene WE, Markum AC, Samadpour M, 2004. Outbreak of Pseudomonas aeruginosa infections caused by commercial piercing of upper ear cartilage. JAMA 291 :981–985.
-
12
Caksen H, Odabas D, 2002. Perforation of the nasal septum and palatum durum in a severely malnourished infant. Pediatr Dermatol 19 :89–90.
-
13
Marsden PD, 1986. Mucosal leishmaniasis (“espundia” Escomel, 1911). Trans R Soc Trop Med Hyg 80 :859–876.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 323 | 263 | 27 |
| Full Text Views | 431 | 9 | 0 |
| PDF Downloads | 177 | 8 | 0 |