LETTERS TO THE EDITOR

François Nosten Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Center for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK
Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand
Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Center for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Center for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK

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Robert Hutagalung Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Center for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK
Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand
Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Center for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Center for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK

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Verena Illiona Carrara Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Center for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK
Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand
Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Center for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Center for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK

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Elizabeth Ashley Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Center for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK
Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand
Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Center for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Center for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK

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Nicholas White Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Center for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK
Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand
Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
Shoklo Malaria Research Unit, Mae Sot, Tak Province, Thailand; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Center for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Center for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK

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Author Notes

  • 1

    Dondorp A, Nosten F, Stepniewska K, Day N, White N, 2005. Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial. Lancet 366 :717–725.

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  • 2

    Hutagalung R, Htoo H, Nwee P, Arunkamomkiri J, Zwang J, Carrara IV, Ashley E, Singhasivanon P, White NJ, Nosten F, 2006. A case control auditory evaluation of patients treated with artemether-lumefantrine. Am J Trop Med Hyg 74 :211–214.

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  • 3

    Petras JM, Kyle DE, Gettayacamin M, Young GD, Bauman RA, Webster HK, Corcoran KD, Peggins JO, Vane MA, Brewer TG, 1997. Arteether: risks of two-week administration in Macaca mulatta. Am J Trop Med Hyg 56 :390–396.

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  • 4

    Kager PA, Schultz MJ, Zijlstra EE, van den Berg B, van Boxtel CJ, 1994. Arteether administration in humans: preliminary studies of pharmacokinetics, safety and tolerance. Trans R Soc Trop Med Hyg 88 (Suppl 1):S53–S54.

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  • 5

    Toovey S, Jamieson A, 2004. Audiometric changes associated with the treatment of uncomplicated falciparum malaria with co-artemether. Trans R Soc Trop Med Hyg 98 :261–267.

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  • 6

    Kissinger E, Hien TT, Hung NT, Nam ND, Tuyen NL, Dinh BV, Mann C, Phu NH, Loc PP, Simpson JA, White NJ, Farrar JJ, 2000. Clinical and neurophysiological study of the effects of multiple doses of artemisinin on brain-stem function in Vietnamese patients. Am J Trop Med Hyg 63 :48–55.

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  • 7

    van Vugt M, Angus BJ, Price RN, Mann C, Simpson JA, Poletto C, Htoo SE, Looareesuwan S, White NJ, Nosten F, 2000. A case-control auditory evaluation of patients treated with artemisinin derivatives for multidrug-resistant Plasmodium falciparum malaria. Am J Trop Med Hyg 62 :65–69.

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  • 8

    Hien TT, Turner GD, Mai NT, Phu NH, Bethell D, Blakemore WF, Cavanagh JB, Dayan A, Medana I, Weller RO, Day NP, White NJ, 2003. Neuropathological assessment of artemether-treated severe malaria. Lancet 362 :295–296.

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  • 9

    Hien TT, Day NP, Nguyen HP, Nguyen TH, Pham PL, Dinh XS, Ly VC, Ha V, Waller D, Peto TE, White NJ, 1996. A controlled trial of artemether or quinine in Vietnamese adults with severe falciparum malaria. N Engl J Med 335 :76–83.

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