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1
Punyagupta S, Juttijudata P, Bunnag T, 1975. Eosinophilic meningitis in Thailand. Clinical studies of 484 typical cases probably caused by Angiostrongylus cantonensis. Am J Trop Med Hyg 24 :921–931.
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2
Chotmongkol V, Sawanyawisuth K, Thavornpitak Y, 2000. Corticosteroid treatment of eosinophilic meningitis. Clin Infect Dis 31 :660–662.
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3
Cuckler AC, Egerton JR, Alicata JE, 1965. Therapeutic effects of thiabendazole on Angiostrongylus cantonensis infection in rats. J Parasitol 51 :392–396.
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4
Maki J, Yanagisawa T, 1986. Studies on antihelmintic effects of flubendazole and mebendazole on the rat lung worm Angiostrongylus cantonensis in mice and rats. J Parasitol 72 :512–516.
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5
Hwang KP, Chen ER, 1988. Larvicidal effects of albendazole against Angiostrongylus cantonensis in mice. Am J Trop Med Hyg 39 :191–195.
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6
Kliks MM, Kroenke K, Hardman JM, 1982. Eosinophilic radiculomyeloencephalitis: an angiostrongyliasis outbreak in American Samoa related to ingestion of Achatina fulica snails. Am J Trop Med Hyg 31 :1114–1122.
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7
Hwang KP, Chen ER, 1991. Clinical studies on Angiostrongyliasis cantonensis among children in Taiwan. Southeast Asian J Trop Med Public Health 22 (Suppl):194–199.
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8
Chotmongkol V, Wongjitrat C, Sawadpanit K, Sawanyawisuth K, 2004. Treatment of eosinophilic meningitis with a combination of albendazole and corticosteroid. Southeast Asian J Trop Med Public Health 35 :172–174.
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9
Tsai HC, Liu YC, Kunin CM, Lee SS, Chen YS, Lin HH, Tsai TH, Lin WR, Huang CK, Yen MY, Yen CM, 2001. Eosinophilic meningitis caused by Angiostrongylus cantonensis: report of 17 cases. Am J Med 111 :109–114.
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10
Maleewong W, Sombatsawat P, Intapan PM, Wongkham C, Chotmongkol V, 2001. Immunoblot evaluation of the specific of the 29 kDa antigen from young adult female worms Angiostrongylus cantonensis for immunodiagnosis of human angiostrongyliasis. Asian Pac J Allergy Immunol 19 :267–273.
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TREATMENT OF EOSINOPHILIC MENINGITIS WITH A COMBINATION OF PREDNISOLONE AND MEBENDAZOLE
VERAJIT CHOTMONGKOL
VERAJIT CHOTMONGKOL
Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
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KOOKWAN SAWADPANITCH
KOOKWAN SAWADPANITCH
Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
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KITTISAK SAWANYAWISUTH
KITTISAK SAWANYAWISUTH
Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
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SITICHOKE LOUHAWILAI
SITICHOKE LOUHAWILAI
Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
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PANITA LIMPAWATTANA
PANITA LIMPAWATTANA
Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
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To study the efficacy of the combination of prednisolone and mebendazole for the treatment of eosinophilic meningitis, we conducted a pilot study among Thai patients with eosinophilic meningitis. Patients were given a two-week course of prednisolone, 60 mg/day, and mebendazole, 10 mg/kg/day. The primary observation parameter was the number of patients who still had headaches after the two-week course of treatment. Forty-one patients were enrolled in the study. Four (10%) patients still had headaches after the two-week course of treatment and the median length of time until complete disappearance of headaches was three days. Serious side effects were not detected. Treatment for two weeks with the combination regimen of prednisolone and mebendazole is safe and beneficial in relieving headaches in patients with eosinophilic meningitis.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
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-
1
Punyagupta S, Juttijudata P, Bunnag T, 1975. Eosinophilic meningitis in Thailand. Clinical studies of 484 typical cases probably caused by Angiostrongylus cantonensis. Am J Trop Med Hyg 24 :921–931.
-
2
Chotmongkol V, Sawanyawisuth K, Thavornpitak Y, 2000. Corticosteroid treatment of eosinophilic meningitis. Clin Infect Dis 31 :660–662.
-
3
Cuckler AC, Egerton JR, Alicata JE, 1965. Therapeutic effects of thiabendazole on Angiostrongylus cantonensis infection in rats. J Parasitol 51 :392–396.
-
4
Maki J, Yanagisawa T, 1986. Studies on antihelmintic effects of flubendazole and mebendazole on the rat lung worm Angiostrongylus cantonensis in mice and rats. J Parasitol 72 :512–516.
-
5
Hwang KP, Chen ER, 1988. Larvicidal effects of albendazole against Angiostrongylus cantonensis in mice. Am J Trop Med Hyg 39 :191–195.
-
6
Kliks MM, Kroenke K, Hardman JM, 1982. Eosinophilic radiculomyeloencephalitis: an angiostrongyliasis outbreak in American Samoa related to ingestion of Achatina fulica snails. Am J Trop Med Hyg 31 :1114–1122.
-
7
Hwang KP, Chen ER, 1991. Clinical studies on Angiostrongyliasis cantonensis among children in Taiwan. Southeast Asian J Trop Med Public Health 22 (Suppl):194–199.
-
8
Chotmongkol V, Wongjitrat C, Sawadpanit K, Sawanyawisuth K, 2004. Treatment of eosinophilic meningitis with a combination of albendazole and corticosteroid. Southeast Asian J Trop Med Public Health 35 :172–174.
-
9
Tsai HC, Liu YC, Kunin CM, Lee SS, Chen YS, Lin HH, Tsai TH, Lin WR, Huang CK, Yen MY, Yen CM, 2001. Eosinophilic meningitis caused by Angiostrongylus cantonensis: report of 17 cases. Am J Med 111 :109–114.
-
10
Maleewong W, Sombatsawat P, Intapan PM, Wongkham C, Chotmongkol V, 2001. Immunoblot evaluation of the specific of the 29 kDa antigen from young adult female worms Angiostrongylus cantonensis for immunodiagnosis of human angiostrongyliasis. Asian Pac J Allergy Immunol 19 :267–273.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 25 | 25 | 9 |
| Full Text Views | 402 | 157 | 0 |
| PDF Downloads | 134 | 35 | 0 |