RISK FACTORS FOR FOLLOW-UP INTERRUPTION OF HIV PATIENTS IN FRENCH GUIANA

MATHIEU NACHER Centre d’Information et de Soins de l’Immunodéficience Humaine (CISIH) de Guyane, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Hôpital de Jour Adultes, Centre Hospitalier Andrée Rosemon, Rue des Flamboyants, Cayenne, French Guiana; Service de Médecine, Centre Hospitalier Frank Joly, Saint Laurent du Maroni, French Guiana; Service de Médecine, Centre Médico Chirurgical de Kourou, Kourou, French Guiana; Département d’Information Médicale, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Service de Dermatologie, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana

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MYRIAM EL GUEDJ Centre d’Information et de Soins de l’Immunodéficience Humaine (CISIH) de Guyane, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Hôpital de Jour Adultes, Centre Hospitalier Andrée Rosemon, Rue des Flamboyants, Cayenne, French Guiana; Service de Médecine, Centre Hospitalier Frank Joly, Saint Laurent du Maroni, French Guiana; Service de Médecine, Centre Médico Chirurgical de Kourou, Kourou, French Guiana; Département d’Information Médicale, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Service de Dermatologie, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana

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TANIA VAZ Centre d’Information et de Soins de l’Immunodéficience Humaine (CISIH) de Guyane, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Hôpital de Jour Adultes, Centre Hospitalier Andrée Rosemon, Rue des Flamboyants, Cayenne, French Guiana; Service de Médecine, Centre Hospitalier Frank Joly, Saint Laurent du Maroni, French Guiana; Service de Médecine, Centre Médico Chirurgical de Kourou, Kourou, French Guiana; Département d’Information Médicale, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Service de Dermatologie, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana

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VALÉRY NASSER Centre d’Information et de Soins de l’Immunodéficience Humaine (CISIH) de Guyane, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Hôpital de Jour Adultes, Centre Hospitalier Andrée Rosemon, Rue des Flamboyants, Cayenne, French Guiana; Service de Médecine, Centre Hospitalier Frank Joly, Saint Laurent du Maroni, French Guiana; Service de Médecine, Centre Médico Chirurgical de Kourou, Kourou, French Guiana; Département d’Information Médicale, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Service de Dermatologie, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana

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ANDRY RANDRIANJOHANY Centre d’Information et de Soins de l’Immunodéficience Humaine (CISIH) de Guyane, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Hôpital de Jour Adultes, Centre Hospitalier Andrée Rosemon, Rue des Flamboyants, Cayenne, French Guiana; Service de Médecine, Centre Hospitalier Frank Joly, Saint Laurent du Maroni, French Guiana; Service de Médecine, Centre Médico Chirurgical de Kourou, Kourou, French Guiana; Département d’Information Médicale, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Service de Dermatologie, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana

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FERNAND ALVAREZ Centre d’Information et de Soins de l’Immunodéficience Humaine (CISIH) de Guyane, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Hôpital de Jour Adultes, Centre Hospitalier Andrée Rosemon, Rue des Flamboyants, Cayenne, French Guiana; Service de Médecine, Centre Hospitalier Frank Joly, Saint Laurent du Maroni, French Guiana; Service de Médecine, Centre Médico Chirurgical de Kourou, Kourou, French Guiana; Département d’Information Médicale, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Service de Dermatologie, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana

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MILKO SOBESKY Centre d’Information et de Soins de l’Immunodéficience Humaine (CISIH) de Guyane, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Hôpital de Jour Adultes, Centre Hospitalier Andrée Rosemon, Rue des Flamboyants, Cayenne, French Guiana; Service de Médecine, Centre Hospitalier Frank Joly, Saint Laurent du Maroni, French Guiana; Service de Médecine, Centre Médico Chirurgical de Kourou, Kourou, French Guiana; Département d’Information Médicale, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Service de Dermatologie, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana

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CHRISTIAN MAGNIEN Centre d’Information et de Soins de l’Immunodéficience Humaine (CISIH) de Guyane, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Hôpital de Jour Adultes, Centre Hospitalier Andrée Rosemon, Rue des Flamboyants, Cayenne, French Guiana; Service de Médecine, Centre Hospitalier Frank Joly, Saint Laurent du Maroni, French Guiana; Service de Médecine, Centre Médico Chirurgical de Kourou, Kourou, French Guiana; Département d’Information Médicale, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Service de Dermatologie, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana

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PIERRE COUPPIÉ Centre d’Information et de Soins de l’Immunodéficience Humaine (CISIH) de Guyane, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Hôpital de Jour Adultes, Centre Hospitalier Andrée Rosemon, Rue des Flamboyants, Cayenne, French Guiana; Service de Médecine, Centre Hospitalier Frank Joly, Saint Laurent du Maroni, French Guiana; Service de Médecine, Centre Médico Chirurgical de Kourou, Kourou, French Guiana; Département d’Information Médicale, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Service de Dermatologie, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana

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French Guiana is the region of France where the HIV epidemic is most prevalent. To determine the risk factors for being lost for follow-up, we followed a cohort of 1,213 patients between 1992 and 2002 and determined which variables were related to two definitions of being lost to follow-up: permanently disappearing from HIV clinics and coming back after more than 1 year of missed appointments. The incidence rate for permanent follow-up interruption was 17.2 per 100 person-years. The median time to lost to follow-up was 4.3 years (interquartile range = 1.4–8.4 years). Cox modeling showed that the younger age groups, foreigners, patients with initial CD4 counts at the time of HIV diagnosis less than 500/mm3, and patients followed before the availability of highly active antiretroviral therapy (HAART) were significantly more likely to be permanently lost to follow-up, suggesting that some of the patients may have died. When looking at temporary loss to follow-up, younger age groups, untreated patients, patients consulting before the availability of HAART, and patients with CD4 counts more than 500/mm3 were more likely to not come back for a period of more than 1 year.

Author Notes

  • 1

    Delfraissy JF, 2002. Prise en Charge des Personnes Infectées par le VIH. Paris, France: Médecine-Sciences Flammarion.

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  • 2

    2003. Programme Regional de Santé VIH-SIDA en Guyane: Direction de la Santé et du Développement Social. Cayenne, French Guiana.

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  • 3

    UNAIDS, Available online at http://www.unaids.org/EN/geographical+Area/By+Region/latin_america.asp. Accessed May 12, 2005.

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  • 4

    Institut National de la Statistique et des Études Économiques (INSEE), 2004. Available online at http://www.insee.fr/fr/insee_regions/guyane/home/home_page.asp. Accessed May 12, 2005.

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  • 5

    Giraud MGA, 1995. Analysis of Sexual Behaviour in the French Antilles and French Guiana. Agence Nationale du Recherches sur le Sida et les Hépatites, Paris, France.

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  • 6

    Couppié P, Clyti E, El Guedj M, Sobesky M, Pradinaud R, 2000. Social factors associated with bad follow-up with HIV+ patients in French Guiana. XIIIth International AIDS Conference, Barcelona, Spain, July 7–12, 2002.

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  • 7

    Stone VE, 2004. Optimizing the care of minority patients with HIV/AIDS. Clin Infect Dis 38 :400–404.

  • 8

    Catz SL, McClure JB, Jones GN, Brantley PJ, 1999. Predictors of outpatient medical appointment attendance among persons with HIV. AIDS Care 11 :361–373.s

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