PRESCRIPTION AND ADMINISTRATION OF A 14-DAY REGIMEN OF ZINC TREATMENT FOR CHILDHOOD DIARRHEA IN MALI

PETER J. WINCH Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Faculty of Medicine/Malaria Research and Training Center, Bamako, Mali; Save the Children, Bougouni, Mali and Westport, Connecticut; World Health Organization, Department of Child and Adolescent Health and Development, Geneva, Switzerland

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KATE E. GILROY Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Faculty of Medicine/Malaria Research and Training Center, Bamako, Mali; Save the Children, Bougouni, Mali and Westport, Connecticut; World Health Organization, Department of Child and Adolescent Health and Development, Geneva, Switzerland

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SEYDOU DOUMBIA Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Faculty of Medicine/Malaria Research and Training Center, Bamako, Mali; Save the Children, Bougouni, Mali and Westport, Connecticut; World Health Organization, Department of Child and Adolescent Health and Development, Geneva, Switzerland

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AMY E. PATTERSON Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Faculty of Medicine/Malaria Research and Training Center, Bamako, Mali; Save the Children, Bougouni, Mali and Westport, Connecticut; World Health Organization, Department of Child and Adolescent Health and Development, Geneva, Switzerland

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ZANA DAOU Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Faculty of Medicine/Malaria Research and Training Center, Bamako, Mali; Save the Children, Bougouni, Mali and Westport, Connecticut; World Health Organization, Department of Child and Adolescent Health and Development, Geneva, Switzerland

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SEYON COULIBALY Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Faculty of Medicine/Malaria Research and Training Center, Bamako, Mali; Save the Children, Bougouni, Mali and Westport, Connecticut; World Health Organization, Department of Child and Adolescent Health and Development, Geneva, Switzerland

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ERIC SWEDBERG Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Faculty of Medicine/Malaria Research and Training Center, Bamako, Mali; Save the Children, Bougouni, Mali and Westport, Connecticut; World Health Organization, Department of Child and Adolescent Health and Development, Geneva, Switzerland

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ROBERT E. BLACK Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Faculty of Medicine/Malaria Research and Training Center, Bamako, Mali; Save the Children, Bougouni, Mali and Westport, Connecticut; World Health Organization, Department of Child and Adolescent Health and Development, Geneva, Switzerland

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OLIVIER FONTAINE Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; Faculty of Medicine/Malaria Research and Training Center, Bamako, Mali; Save the Children, Bougouni, Mali and Westport, Connecticut; World Health Organization, Department of Child and Adolescent Health and Development, Geneva, Switzerland

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We evaluated prescription and correct dosing of a 14-day course of dispersible zinc tablets prescribed to young children with diarrhea by community and facility workers in rural, southern Mali, West Africa. One hundred twenty-three children were followed at home on days 3 and 14 after being prescribed zinc. The age-appropriate dose of zinc was dispensed in 94% of cases. Ninety-five percent of mothers dissolved the tablet in a small amount of water and gave it with a spoon. Only eight caretakers reported problems with zinc administration: either vomiting or refusal to take the tablets. Sixty-four percent of children received the full 14-day course of treatment, and more than 89% of children were given at least a 10-day course of zinc treatment. The levels of correct administration were very good but might be lower under non-research conditions.

Author Notes

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