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Reference Manager
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-
1
World Health Organization, 2000. WHO expert committee on malaria. World Health Organ Tech Rep Ser 892 :1–71.
-
2
Hemingway J, Hawkes NJ, McCaroll L, Ranson H, 2004. The molecular basis of insecticide resistance in mosquitoes. Insect Biochem Mol Biol 34 :653–665.
-
3
Martinez-Torres D, Chandre F, Williamson MS, Darriet F, Bergé JB, Devonshire AL, Guillet P, Pasteur N, Pauron D, 1998. Molecular characterisation of pyrethroid knockdown resistance (kdr) in the major malaria vector Anopheles gambiae s. s. Insect Mol Biol 7 :179–184.
-
4
Chandre F, Manguin S, Brengues C, Dossou Yovo J, Darriet F, Diabate A, Carnevale P, Guillet P, 1999. Current distribution of pyrethroid resistance gene (Kdr) in Anopheles gambiae complex from West Africa and further evidence for reproductive isolation of Mopti form. Parassitologia 41 :319–322.
-
5
Ranson H, Jensen B, Vulule J, Wang X, Hemingway J, Collins F, 2000. Identification of a point mutation in the voltage-gated sodium channel gene of Kenyan Anopheles gambiae associated with resistance to DDT and pyrethroids. Insect Mol Biol 9 :491–497.
-
6
Etang J, Manga L, Chandre F, Guillet P, Fondjo E, Mimpfoundi R, Toto JC, Fontenille D, 2003. Insecticide susceptibility status of Anopheles gambiae s.l. (Diptera: Culicidae) in the Republic of Cameroon. J Med Entomol 40 :491–497.
-
7
Gentile G, Santolamazza F, Fanello C, Petrarca V, Caccone A, Della Torre A, 2004. Variation in an intron sequence of voltage-gate sodium channel gene correlates with genetic differentiation between Anopheles gambiae s.s. molecular forms. Insect Mol Biol 13 :371–377.
-
8
Reimer LJ, Tripet F, Slotman M, Spielman A, Lanzaro GC, 2005. An unusual distribution of kdr gene among populations of Anopheles gambiae on the island of Bioko, Equatorial Guinea. Insect Mol Biol 14 :683–688.
-
9
Gillies MT, de Meillon B, 1968. The anophelinae of Africa south of the Sahara. Publ S Afr Inst Med Res 54 :31–343.
-
10
World Health Organization, 1998. Tests Procedures for Insecticide Resistance Monitoring in Malaria Vectors, Bio-Efficacy and Persistence of Insecticides on Treated Surfaces. Report of the WHO Informal Consultation. Geneva: World Health Organization.
-
11
Fanello C, Santolamazza F, della Torre A, 2002. Simultaneous identification of species and molecular forms of the Anopheles gambiae complex by PCR-RFLP. Med Vet Entomol 16 :461–464.
-
12
Coetzee M, Craig M, le Sueur D, 2000. Distribution of African malaria mosquitoes belonging to the Anopheles gambiae complex. Parasitol Today 16 :74–77.
-
13
Wondji C, Simard F, Petrarca V, Etang J, Santolamazza F, della Torre A, Fontenille D, 2005. Species and populations of the Anopheles gambiae complex in Cameroon with special emphasis on chromosomal and molecular forms of Anopheles gambiae s.s. J Med Entomol 42 :998–1005.
-
14
Lynd A, Ranson H, McCall PJ, Randle P, Black WC IV, Walker ED, Donnelly MJ, 2005. A simplified high-throughput method for pyrethroid knock-down resistance (kdr) detection in Anopheles gambiae. Malar J 4 :16.
-
15
Diabate A, Brengues C, Baldet T, Dabiré RK, Hougard JM, Akogbeto M, Kengne P, Simard F, Guillet P, Hemingway J, Chandre F, 2004. The spread of the Leu-Phe kdr mutation through Anopheles gambiae complex in Burkina Faso: genetic introgression and de novo phenomena. Trop Med Int Health 9 :1267–1273.
-
16
Yawson AE, McCall PJ, Wilson MD, Donnelly MJ, 2004. Species abundance and insecticide resistance of Anopheles gambiae in selected areas of Ghana and Burkina Faso. Med Vet Entomol 18 :372–377.
-
17
Weill M, Chandre F, Brengues C, Manguin S, Akogbeto M, Pasteur N, Guillet P, Raymond M, 2000. The Kdr mutation occurs in the Mopti form of Anopheles gambiae s.s. through introgression. Insect Mol Biol 9 :451–455.
-
18
Awolola TS, Oyewole IO, Amajoh CN, Idowu ET, Ajayi MB, Oduola A, Manafa OU, Koekemoer LL, Coetzee M, 2005. Distribution of the molecular forms of Anopheles gambiae and pyrethroid knock down resistance gene in Nigeria. Acta Trop 95 :204–205.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 186 | 130 | 6 |
| Full Text Views | 329 | 3 | 0 |
| PDF Downloads | 73 | 3 | 0 |
FIRST REPORT OF KNOCKDOWN MUTATIONS IN THE MALARIA VECTOR ANOPHELES GAMBIAE FROM CAMEROON
JOSIANE ETANG
JOSIANE ETANG
Organisation de Coordination pour la Lutte contre les Endémies en Afrique Centrale, Yaounde, Cameroon; Institute of Medical Research and Studies of Medicinal Plants, Ministry of Scientific Research and Innovation, Yaounde, Cameroon; National Malaria Control Program, Ministry of Health, Yaounde, Cameroon; Centre de Recherches Entomologiques de Cotonou, Cotonou, Benin; Institut de Recherche pour le Développement, Research Unit 016, Montpellier, France
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ETIENNE FONDJO
ETIENNE FONDJO
Organisation de Coordination pour la Lutte contre les Endémies en Afrique Centrale, Yaounde, Cameroon; Institute of Medical Research and Studies of Medicinal Plants, Ministry of Scientific Research and Innovation, Yaounde, Cameroon; National Malaria Control Program, Ministry of Health, Yaounde, Cameroon; Centre de Recherches Entomologiques de Cotonou, Cotonou, Benin; Institut de Recherche pour le Développement, Research Unit 016, Montpellier, France
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FABRICE CHANDRE
FABRICE CHANDRE
Organisation de Coordination pour la Lutte contre les Endémies en Afrique Centrale, Yaounde, Cameroon; Institute of Medical Research and Studies of Medicinal Plants, Ministry of Scientific Research and Innovation, Yaounde, Cameroon; National Malaria Control Program, Ministry of Health, Yaounde, Cameroon; Centre de Recherches Entomologiques de Cotonou, Cotonou, Benin; Institut de Recherche pour le Développement, Research Unit 016, Montpellier, France
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ISABELLE MORLAIS
ISABELLE MORLAIS
Organisation de Coordination pour la Lutte contre les Endémies en Afrique Centrale, Yaounde, Cameroon; Institute of Medical Research and Studies of Medicinal Plants, Ministry of Scientific Research and Innovation, Yaounde, Cameroon; National Malaria Control Program, Ministry of Health, Yaounde, Cameroon; Centre de Recherches Entomologiques de Cotonou, Cotonou, Benin; Institut de Recherche pour le Développement, Research Unit 016, Montpellier, France
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CECILE BRENGUES
CECILE BRENGUES
Organisation de Coordination pour la Lutte contre les Endémies en Afrique Centrale, Yaounde, Cameroon; Institute of Medical Research and Studies of Medicinal Plants, Ministry of Scientific Research and Innovation, Yaounde, Cameroon; National Malaria Control Program, Ministry of Health, Yaounde, Cameroon; Centre de Recherches Entomologiques de Cotonou, Cotonou, Benin; Institut de Recherche pour le Développement, Research Unit 016, Montpellier, France
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PHILIPPE NWANE
PHILIPPE NWANE
Organisation de Coordination pour la Lutte contre les Endémies en Afrique Centrale, Yaounde, Cameroon; Institute of Medical Research and Studies of Medicinal Plants, Ministry of Scientific Research and Innovation, Yaounde, Cameroon; National Malaria Control Program, Ministry of Health, Yaounde, Cameroon; Centre de Recherches Entomologiques de Cotonou, Cotonou, Benin; Institut de Recherche pour le Développement, Research Unit 016, Montpellier, France
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MOUHAMADOU CHOUAIBOU
MOUHAMADOU CHOUAIBOU
Organisation de Coordination pour la Lutte contre les Endémies en Afrique Centrale, Yaounde, Cameroon; Institute of Medical Research and Studies of Medicinal Plants, Ministry of Scientific Research and Innovation, Yaounde, Cameroon; National Malaria Control Program, Ministry of Health, Yaounde, Cameroon; Centre de Recherches Entomologiques de Cotonou, Cotonou, Benin; Institut de Recherche pour le Développement, Research Unit 016, Montpellier, France
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HAMADOU NDJEMAI
HAMADOU NDJEMAI
Organisation de Coordination pour la Lutte contre les Endémies en Afrique Centrale, Yaounde, Cameroon; Institute of Medical Research and Studies of Medicinal Plants, Ministry of Scientific Research and Innovation, Yaounde, Cameroon; National Malaria Control Program, Ministry of Health, Yaounde, Cameroon; Centre de Recherches Entomologiques de Cotonou, Cotonou, Benin; Institut de Recherche pour le Développement, Research Unit 016, Montpellier, France
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FRÉDÉRIC SIMARD
FRÉDÉRIC SIMARD
Organisation de Coordination pour la Lutte contre les Endémies en Afrique Centrale, Yaounde, Cameroon; Institute of Medical Research and Studies of Medicinal Plants, Ministry of Scientific Research and Innovation, Yaounde, Cameroon; National Malaria Control Program, Ministry of Health, Yaounde, Cameroon; Centre de Recherches Entomologiques de Cotonou, Cotonou, Benin; Institut de Recherche pour le Développement, Research Unit 016, Montpellier, France
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We report the first finding of the knockdown Leu-Phe and Leu-Ser mutations associated with resistance to pyrethroids and DDT insecticides in the malaria mosquito Anopheles gambiae from Cameroon. The Leu-Phe mutation was found in both the M and S molecular forms of An. gambiae. Importantly, two specimens of the S molecular form were found to carry both mutations in a heterozygous state.
Author Notes
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-
1
World Health Organization, 2000. WHO expert committee on malaria. World Health Organ Tech Rep Ser 892 :1–71.
-
2
Hemingway J, Hawkes NJ, McCaroll L, Ranson H, 2004. The molecular basis of insecticide resistance in mosquitoes. Insect Biochem Mol Biol 34 :653–665.
-
3
Martinez-Torres D, Chandre F, Williamson MS, Darriet F, Bergé JB, Devonshire AL, Guillet P, Pasteur N, Pauron D, 1998. Molecular characterisation of pyrethroid knockdown resistance (kdr) in the major malaria vector Anopheles gambiae s. s. Insect Mol Biol 7 :179–184.
-
4
Chandre F, Manguin S, Brengues C, Dossou Yovo J, Darriet F, Diabate A, Carnevale P, Guillet P, 1999. Current distribution of pyrethroid resistance gene (Kdr) in Anopheles gambiae complex from West Africa and further evidence for reproductive isolation of Mopti form. Parassitologia 41 :319–322.
-
5
Ranson H, Jensen B, Vulule J, Wang X, Hemingway J, Collins F, 2000. Identification of a point mutation in the voltage-gated sodium channel gene of Kenyan Anopheles gambiae associated with resistance to DDT and pyrethroids. Insect Mol Biol 9 :491–497.
-
6
Etang J, Manga L, Chandre F, Guillet P, Fondjo E, Mimpfoundi R, Toto JC, Fontenille D, 2003. Insecticide susceptibility status of Anopheles gambiae s.l. (Diptera: Culicidae) in the Republic of Cameroon. J Med Entomol 40 :491–497.
-
7
Gentile G, Santolamazza F, Fanello C, Petrarca V, Caccone A, Della Torre A, 2004. Variation in an intron sequence of voltage-gate sodium channel gene correlates with genetic differentiation between Anopheles gambiae s.s. molecular forms. Insect Mol Biol 13 :371–377.
-
8
Reimer LJ, Tripet F, Slotman M, Spielman A, Lanzaro GC, 2005. An unusual distribution of kdr gene among populations of Anopheles gambiae on the island of Bioko, Equatorial Guinea. Insect Mol Biol 14 :683–688.
-
9
Gillies MT, de Meillon B, 1968. The anophelinae of Africa south of the Sahara. Publ S Afr Inst Med Res 54 :31–343.
-
10
World Health Organization, 1998. Tests Procedures for Insecticide Resistance Monitoring in Malaria Vectors, Bio-Efficacy and Persistence of Insecticides on Treated Surfaces. Report of the WHO Informal Consultation. Geneva: World Health Organization.
-
11
Fanello C, Santolamazza F, della Torre A, 2002. Simultaneous identification of species and molecular forms of the Anopheles gambiae complex by PCR-RFLP. Med Vet Entomol 16 :461–464.
-
12
Coetzee M, Craig M, le Sueur D, 2000. Distribution of African malaria mosquitoes belonging to the Anopheles gambiae complex. Parasitol Today 16 :74–77.
-
13
Wondji C, Simard F, Petrarca V, Etang J, Santolamazza F, della Torre A, Fontenille D, 2005. Species and populations of the Anopheles gambiae complex in Cameroon with special emphasis on chromosomal and molecular forms of Anopheles gambiae s.s. J Med Entomol 42 :998–1005.
-
14
Lynd A, Ranson H, McCall PJ, Randle P, Black WC IV, Walker ED, Donnelly MJ, 2005. A simplified high-throughput method for pyrethroid knock-down resistance (kdr) detection in Anopheles gambiae. Malar J 4 :16.
-
15
Diabate A, Brengues C, Baldet T, Dabiré RK, Hougard JM, Akogbeto M, Kengne P, Simard F, Guillet P, Hemingway J, Chandre F, 2004. The spread of the Leu-Phe kdr mutation through Anopheles gambiae complex in Burkina Faso: genetic introgression and de novo phenomena. Trop Med Int Health 9 :1267–1273.
-
16
Yawson AE, McCall PJ, Wilson MD, Donnelly MJ, 2004. Species abundance and insecticide resistance of Anopheles gambiae in selected areas of Ghana and Burkina Faso. Med Vet Entomol 18 :372–377.
-
17
Weill M, Chandre F, Brengues C, Manguin S, Akogbeto M, Pasteur N, Guillet P, Raymond M, 2000. The Kdr mutation occurs in the Mopti form of Anopheles gambiae s.s. through introgression. Insect Mol Biol 9 :451–455.
-
18
Awolola TS, Oyewole IO, Amajoh CN, Idowu ET, Ajayi MB, Oduola A, Manafa OU, Koekemoer LL, Coetzee M, 2005. Distribution of the molecular forms of Anopheles gambiae and pyrethroid knock down resistance gene in Nigeria. Acta Trop 95 :204–205.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 186 | 130 | 6 |
| Full Text Views | 329 | 3 | 0 |
| PDF Downloads | 73 | 3 | 0 |