VARICELLA ZOSTER VIRUS MENINGITIS COMPLICATING SODIUM STIBOGLUCONATE TREATMENT FOR CUTANEOUS LEISHMANIASIS

JOSHUA D. HARTZELL Department of Internal Medicine, Walter Reed Army Medical Center, Washington D.C.; Uniformed Services University of the Health Sciences, Bethesda, Maryland; Department of Neurology, Walter Reed Army Medical Center, Washington, D.C.; Infectious Diseases Division, Uniformed Services University of the Health Sciences, Bethesda, Maryland; Infectious Diseases Service, National Naval Medical Center, Bethesda, Maryland; Infectious Diseases Service, Walter Reed Army Medical Center, Washington, D.C.

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NAOMI E. ARONSON Department of Internal Medicine, Walter Reed Army Medical Center, Washington D.C.; Uniformed Services University of the Health Sciences, Bethesda, Maryland; Department of Neurology, Walter Reed Army Medical Center, Washington, D.C.; Infectious Diseases Division, Uniformed Services University of the Health Sciences, Bethesda, Maryland; Infectious Diseases Service, National Naval Medical Center, Bethesda, Maryland; Infectious Diseases Service, Walter Reed Army Medical Center, Washington, D.C.

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SUDHIR NAGARAJA Department of Internal Medicine, Walter Reed Army Medical Center, Washington D.C.; Uniformed Services University of the Health Sciences, Bethesda, Maryland; Department of Neurology, Walter Reed Army Medical Center, Washington, D.C.; Infectious Diseases Division, Uniformed Services University of the Health Sciences, Bethesda, Maryland; Infectious Diseases Service, National Naval Medical Center, Bethesda, Maryland; Infectious Diseases Service, Walter Reed Army Medical Center, Washington, D.C.

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TIM WHITMAN Department of Internal Medicine, Walter Reed Army Medical Center, Washington D.C.; Uniformed Services University of the Health Sciences, Bethesda, Maryland; Department of Neurology, Walter Reed Army Medical Center, Washington, D.C.; Infectious Diseases Division, Uniformed Services University of the Health Sciences, Bethesda, Maryland; Infectious Diseases Service, National Naval Medical Center, Bethesda, Maryland; Infectious Diseases Service, Walter Reed Army Medical Center, Washington, D.C.

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CLIFTON A. HAWKES Department of Internal Medicine, Walter Reed Army Medical Center, Washington D.C.; Uniformed Services University of the Health Sciences, Bethesda, Maryland; Department of Neurology, Walter Reed Army Medical Center, Washington, D.C.; Infectious Diseases Division, Uniformed Services University of the Health Sciences, Bethesda, Maryland; Infectious Diseases Service, National Naval Medical Center, Bethesda, Maryland; Infectious Diseases Service, Walter Reed Army Medical Center, Washington, D.C.

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GLENN WORTMANN Department of Internal Medicine, Walter Reed Army Medical Center, Washington D.C.; Uniformed Services University of the Health Sciences, Bethesda, Maryland; Department of Neurology, Walter Reed Army Medical Center, Washington, D.C.; Infectious Diseases Division, Uniformed Services University of the Health Sciences, Bethesda, Maryland; Infectious Diseases Service, National Naval Medical Center, Bethesda, Maryland; Infectious Diseases Service, Walter Reed Army Medical Center, Washington, D.C.

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Sodium stibogluconate (Pentostam®; GlaxoSmithKline) is a pentavalent antimonial compound used in the treatment of leishmaniasis, which has an association with reactivation of varicella zoster virus (VZV). We report the first known case of an immunocompetent adult who developed VZV aseptic meningitis and dermatomal herpes zoster during treatment with sodium stibogluconate.

Author Notes

Reprint requests: Joshua D. Hartzell, Department of Internal Medicine, 2JO5, Walter Reed Army Medical Center, 6900 Georgia Ave. NW, Washington, D.C. 20307-5001, E-mail: Joshua.hartzell@na.amedd.army.mil.
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