• 1

    Mitchell HM, Li YY, Hu PJ, Liu Q, Chen M, Du GG, Wang ZJ, Lee A, Hazell Sl, 1992. Epidemiology of Helicobacter pylori in southern China: identification of early childhood as the critical period for acquisition. J Infect Dis 166 :149–153.

    • Search Google Scholar
    • Export Citation
  • 2

    Bardhan PK, 1997. Epidemiological features of Helicobacter pylori infection in developing countries. Clin Infect Dis 25 :973–978.

  • 3

    Bodhidatta L, Hoge CW, Churnratanakul S, Nirdnoy W, Sampathanukul P, Tungtaem C, Raktham S, Smith CD, Echeverria P, 1993. Diagnosis of Helicobacter pylori infection in a developing country: comparison of two ELISAs and a seroprevalence study. J Infect Dis 168 :1549–1553.

    • Search Google Scholar
    • Export Citation
  • 4

    Brown LM, Thomas TL, Ma JL, Chang YS, You WC, Liu WD, Zhang L, Pee D, Gail MH, 2002. Helicobacter pylori infection in rural China: demographic, lifestyle and environmental factors. Int J Epidemiol 31 :638–645.

    • Search Google Scholar
    • Export Citation
  • 5

    Malaty HM, Kumagai T, Tanaka E, Ota H, Kiyosawa K, Graham DY, Katsuyama T, 2000. Evidence from a nine-year birth cohort study in Japan of transmission pathways of Helicobacter pylori infection. J Clin Microbiol 38 :1971–1973.

    • Search Google Scholar
    • Export Citation
  • 6

    Lin DB, Nieh WT, Wang HM, Hsiao MW, Ling UP, Changlai SP, Ho MS, You SL, Chen CJ, 1999. Seroepidemiology of Helicobacter pylori infection among preschool children in Taiwan. Am J Trop Med Hyg 61 :554–558.

    • Search Google Scholar
    • Export Citation
  • 7

    Malaty HM, Kim JG, Kim SD, Graham DY, 1996. Prevalence of Helicobacter pylori infection in Korean children: inverse relation to socioeconomic status despite a uniformly high prevalence in adults. Am J Epidemiol 143 :257–262.

    • Search Google Scholar
    • Export Citation
  • 8

    Megraud F, Brassens-Rabbe MP, Denis F, Belbouri A, Hoa DQ, 1989. Seroepidemiology of Campylobacter pylori infection in various populations. J Clin Microbiol 27 :1870–1873.

    • Search Google Scholar
    • Export Citation
  • 9

    Brenner H, Rothenbacher D, Bode G, Adler G, 1998. The individual and joint contributions of Helicobacter pylori infection and family history to the risk for peptic ulcer disease. J Infect Dis 177 :1124–1127.

    • Search Google Scholar
    • Export Citation
  • 10

    Hoang TT, Bengtsson C, Phung DC, Sorberg M, Granstrom M, 2003. Seroprevalence of Helicobacter pylori infection in urban and rural Vietnam. Helicobacter 8 :481–482.

    • Search Google Scholar
    • Export Citation
  • 11

    Hoang TT, Wheeldon TU, Bengtsson C, Phung DC, Sorberg M, Granstrom M, 2004. Enzyme-linked immunosorbent assay for Helicobacter pylori needs adjustment for the population investigated. J Clin Microbiol 42 :627–630.

    • Search Google Scholar
    • Export Citation
  • 12

    Ma JL, You WC, Gail MH, Zhang L, Blot WJ, Chang YS, Jiang J, Liu WD, Hu YR, Brown LM, Xu GW, Fraumenti JF Jr, 1998. Helicobacter pylori infection and mode of transmission in a population at high risk of stomach cancer. Int J Epidemiol 27 :570–573.

    • Search Google Scholar
    • Export Citation
  • 13

    Granstrom M, Tindberg Y, Blennow M, 1997. Seroepidemiology of Helicobacter pylori infection in a cohort of children monitored from 6 months to 11 years of age. J Clin Microbiol 35 :468–470.

    • Search Google Scholar
    • Export Citation
  • 14

    Malaty HM, El Kasabany A, Graham DY, Miller CC, Reddy SG, Srinivasan SR, Yamaoka Y, Berenson GS, 2002. Age at acquisition of Helicobacter pylori infection: a follow-up study from infancy to adulthood. Lancet 359 :931–935.

    • Search Google Scholar
    • Export Citation
  • 15

    Goodman KJ, Correa P, Tengana Aux HJ, Ramirez H, DeLany JP, Guerrero Pepinosa O, Lopez Quinones M, Collazos Parra T, 1996. Helicobacter pylori infection in the Colombian Andes: a population-based study of transmission pathways. Am J Epidemiol 144 :290–299.

    • Search Google Scholar
    • Export Citation
  • 16

    Malaty HM, Logan ND, Graham DY, Ramchatesingh JE, 2001. Helicobacter pylori infection in preschool and school-aged minority children: effect of socioeconomic indicators and breast-feeding practices. Clin Infect Dis 32 :1387–1392.

    • Search Google Scholar
    • Export Citation
  • 17

    McCallion WA, Murray LJ, Bailie AG, Dalzell AM, O’Reilly DP, Bamford KB, 1996. Helicobacter pylori infection in children: relation with current household living conditions. Gut 39 :18–21.

    • Search Google Scholar
    • Export Citation
  • 18

    Okuda M, Miyashiro E, Koike M, Okuda S, Minami K, Yoshikawa N, 2001. Breast-feeding prevents Helicobacter pylori infection in early childhood. Pediatr Int 43 :714–715.

    • Search Google Scholar
    • Export Citation
  • 19

    Rothenbacher D, Bode G, Brenner H, 2002. History of breast-feeding and Helicobacter pylori infection in pre-school children: results of a population-based study from Germany. Int J Epidemiol 31 :632–637.

    • Search Google Scholar
    • Export Citation
  • 20

    Tindberg Y, Bengtsson C, Granath F, Blennow M, Nyren O, Granstrom M, 2001. Helicobacter pylori infection in Swedish school children: lack of evidence of child-to-child transmission outside the family. Gastroenterology 121 :310–316.

    • Search Google Scholar
    • Export Citation
  • 21

    Klein PD, Graham DY, Gaillour A, Opekun AR, Smith EO, 1991. Water source as risk factor for Helicobacter pylori infection in Peruvian children. Gastrointestinal Physiology Working Group. Lancet 337 :1503–1506.

    • Search Google Scholar
    • Export Citation
  • 22

    Chow TK, Lambert JR, Wahlqvist ML, Hsu-Hage BH, 1995.Helicobacter pylori in Melbourne Chinese immigrants: evidence for oral-oral transmission via chopsticks. J Gastroenterol Hepatol 10 :562–569.

    • Search Google Scholar
    • Export Citation
  • 23

    Corrado G, Luzzi I, Lucarelli S, Frediani T, Pacchiarotti C, Cavaliere M, Rea P, Cardi E, 1998. Positive association between Helicobacter pylori infection and food allergy in children. Scand J Gastroenterol 33 :1135–1139.

    • Search Google Scholar
    • Export Citation
  • 24

    Figura N, Perrone A, Gennari C, Orlandini G, Bianciardi L, Giannace R, Vaira D, Vagliasinti M. Rottoli P, 1999. Food allergy and Helicobacter pylori infection. Ital J Gastroenterol Hepatol 31 :186–191.

    • Search Google Scholar
    • Export Citation
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PREVALENCE OF AND FACTORS ASSOCIATED WITH HELICOBACTER PYLORI INFECTION IN CHILDREN IN THE NORTH OF VIETNAM

BANG V. NGUYENPediatric Department, Hanoi Medical University, Hanoi, Vietnam; Digestive Disease Division, National Institute of Epidemiology and Hygiene, Hanoi, Vietnam; Pediatric Department of Saint Antoine, Saint Vincent de Paul Hospital, Catholic University, Lille, France; Neonatology and Gastroenterology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Microbiology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Public Health Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France

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KHANH G. NGUYENPediatric Department, Hanoi Medical University, Hanoi, Vietnam; Digestive Disease Division, National Institute of Epidemiology and Hygiene, Hanoi, Vietnam; Pediatric Department of Saint Antoine, Saint Vincent de Paul Hospital, Catholic University, Lille, France; Neonatology and Gastroenterology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Microbiology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Public Health Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France

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CAM D. PHUNGPediatric Department, Hanoi Medical University, Hanoi, Vietnam; Digestive Disease Division, National Institute of Epidemiology and Hygiene, Hanoi, Vietnam; Pediatric Department of Saint Antoine, Saint Vincent de Paul Hospital, Catholic University, Lille, France; Neonatology and Gastroenterology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Microbiology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Public Health Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France

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ODILE KREMPPediatric Department, Hanoi Medical University, Hanoi, Vietnam; Digestive Disease Division, National Institute of Epidemiology and Hygiene, Hanoi, Vietnam; Pediatric Department of Saint Antoine, Saint Vincent de Paul Hospital, Catholic University, Lille, France; Neonatology and Gastroenterology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Microbiology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Public Health Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France

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NICOLAS KALACHPediatric Department, Hanoi Medical University, Hanoi, Vietnam; Digestive Disease Division, National Institute of Epidemiology and Hygiene, Hanoi, Vietnam; Pediatric Department of Saint Antoine, Saint Vincent de Paul Hospital, Catholic University, Lille, France; Neonatology and Gastroenterology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Microbiology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Public Health Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France

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CHRISTOPHE DUPONTPediatric Department, Hanoi Medical University, Hanoi, Vietnam; Digestive Disease Division, National Institute of Epidemiology and Hygiene, Hanoi, Vietnam; Pediatric Department of Saint Antoine, Saint Vincent de Paul Hospital, Catholic University, Lille, France; Neonatology and Gastroenterology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Microbiology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Public Health Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France

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JOSETTE RAYMONDPediatric Department, Hanoi Medical University, Hanoi, Vietnam; Digestive Disease Division, National Institute of Epidemiology and Hygiene, Hanoi, Vietnam; Pediatric Department of Saint Antoine, Saint Vincent de Paul Hospital, Catholic University, Lille, France; Neonatology and Gastroenterology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Microbiology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Public Health Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France

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GWENAËLLE VIDAL-TRECANPediatric Department, Hanoi Medical University, Hanoi, Vietnam; Digestive Disease Division, National Institute of Epidemiology and Hygiene, Hanoi, Vietnam; Pediatric Department of Saint Antoine, Saint Vincent de Paul Hospital, Catholic University, Lille, France; Neonatology and Gastroenterology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Microbiology Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France; Public Health Department, Cochin–Saint Vincent de Paul Hospital Group, Faculty of Medicine, Descartes University, Paris, France

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The study aimed at evaluating the seroprevalence of and sociodemographic, health, lifestyle, and environmental hygiene conditions associated with Helicobacter pylori infection in Vietnamese children. Data from 824 children, aged from 6 months to 15 years and gastrointestinal symptom free when consulted, admitted to a university hospital, were collected using a structured questionnaire and ELISA test for H. pylori infection. The data were examined using univariate and multivariate analyses. H. pylori seroprevalence was 34.0%. Age groups from 3 to 6 years and older than 6, and number of offspring were positively and independently associated with H. pylori seropositivity [adjusted OR (95% CI): 2.9 (1.5–5.5); 1.9 (1.1–3.1) and 1.8 (1.1–2.6), respectively]. Breastfeeding more than 6 months was negatively and independently associated with H. pylori seropositivity [adjusted OR (95% CI): 0.5 (0.3–0.9)]. Mother’s age, history of allergy, gastro-duodenal disease history in the past, initiating collective life before 6 years, sharing bed with parents and time of bed sharing with parents > 24 months were positively but not independently associated with H. pylori seropositivity. None of the other environmental or lifestyle conditions examined was associated with H. pylori infection. Our results support person-to-person transmission and the role of sociodemographic factors in H. pylori infection.

Author Notes

Reprint requests: Bang V. Nguyen, 299 Giap Bat Street, Hanoi, Vietnam, Telephone: 84 903293212, E-mail: hongbang52@yahoo.com.
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