• 1

    Collins WE, Skinner JC, Pappaioanou M, Broderson JR, Filipski VK, McClure HM, Strobert E, Sutton BB, Stanfill PS, Huong AY, 1988. Sporozoite-induced infections of the Salvador I strain of Plasmodium vivax in Saimiri sciureus boliviensis monkeys. J Parasitol 74 :582–585.

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  • 2

    Collins WE, Morris CL, Richardson BB, Sullivan JS, Galland GG, 1994. Further studies on the sporozoite transmission of the Salvador I strain of Plasmodium vivax. J Parasitol 80 :512–517.

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  • 3

    Collins WE, Nussenzweig RS, Ballou WR, Ruebush TK II, Nardin EH, Chulay JD, Majarian WR, Young JF, Wasserman GF, Bathurst I, Gibson HL, Barr PJ, Hoffman SL, Wasserman SS, Broderson JR, Skinner JC, Procell PM, Filipski VK, Wilson CL, 1989. Immunization of Saimiri sciureus boliviensis monkeys with recombinant vaccines based on the circumsporozoite protein of Plasmodium vivax. Am J Trop Med Hyg 40 :455–464.

    • Search Google Scholar
    • Export Citation
  • 4

    Collins WE, Nussenzweig RS, Ruebush TK II, Bathurst I, Nardin EH, Gibson HL, Campbell GH, Barr PJ, Broderson JR, Skinner JC, Filipski VK, Stanfill PS, Roberts JM, Wilson CL, 1990. Further studies on the immunization of Saimiri sciureus boliviensis monkeys with recombinant vaccines based on the circumsporozoite protein of Plasmodium vivax. Am J Trop Med Hyg 43 :576–583.

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  • 5

    Collins WE, Contacos PG, Guinn EG, Held JR, 1966. Studies on the transmission of simian malarias. I. Transmission of two strains of Plasmodium inui by Anopheles maculatus and A. stephensi. J Parasitol 52 :664–668.

    • Search Google Scholar
    • Export Citation
  • 6

    Earle WC, Perez M, 1932. Enumeration of parasites in the blood of malarial patients. J Lab Clin Med 17 :1124–1130.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

AOTUS NANCYMAAE AS A POTENTIAL MODEL FOR THE TESTING OF ANTI-SPOROZOITE AND LIVER STAGE VACCINES AGAINST PLASMODIUM FALCIPARUM

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  • 1 Division of Parasitic Diseases and Animal Resources Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Atlanta Research and Education Foundation, Atlanta, Georgia

The Santa Lucia strain of Plasmodium falciparum was transmitted to Aotus lemurinus griseimembra, A. azarae boliviensis, A. vociferans, and A. nancymaae monkeys by bite and by intravenous inoculation of sporozoites dissected from Anopheles freeborni, An. stephensi, An. gambiae, An. albimanus, and An. maculatus mosquitoes. The data obtained from these infections indicate that A. nancymaae can be considered a suitable host model when combined with the Santa Lucia strain of P. falciparum for the testing of candidate anti-sporozoite and liver stage vaccines.

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