Q FEVER AND PLASMODIUM FALCIPARUM MALARIA CO-INFECTION IN A PATIENT RETURNING FROM THE COMOROS ARCHIPELAGO

PHILIPPE BROUQUI Service des Maladies Infectieuses et Tropicales, Centre Hospitalier et Universitaire Nord Assistance Publique des Hôpitaux de Marseille, Marseilles, France; Unité des Rickettsies, Centre National de Recherche Scientifique, Unité Mixte de Recherche 6020, Institut Fédératif de Recherche 48, Marseilles, France

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JEAN MARC ROLAIN Service des Maladies Infectieuses et Tropicales, Centre Hospitalier et Universitaire Nord Assistance Publique des Hôpitaux de Marseille, Marseilles, France; Unité des Rickettsies, Centre National de Recherche Scientifique, Unité Mixte de Recherche 6020, Institut Fédératif de Recherche 48, Marseilles, France

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CEDRIC FOUCAULT Service des Maladies Infectieuses et Tropicales, Centre Hospitalier et Universitaire Nord Assistance Publique des Hôpitaux de Marseille, Marseilles, France; Unité des Rickettsies, Centre National de Recherche Scientifique, Unité Mixte de Recherche 6020, Institut Fédératif de Recherche 48, Marseilles, France

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DIDIER RAOULT Service des Maladies Infectieuses et Tropicales, Centre Hospitalier et Universitaire Nord Assistance Publique des Hôpitaux de Marseille, Marseilles, France; Unité des Rickettsies, Centre National de Recherche Scientifique, Unité Mixte de Recherche 6020, Institut Fédératif de Recherche 48, Marseilles, France

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Although Plasmodium falciparum malaria and Q fever are both prevalent in Africa, there have been no reports of co-infection to date. We report a case who returned from the Comoros archipelago diagnosed by serologic analysis as well as detection of Coxiella burnetii DNA in acute-phase serum. Thus, Q fever may be associated with malaria infection in travelers returning from disease-endemic countries. This diagnosis should be considered when the response to malaria treatment is incomplete.

  • 1

    Ouledi A, 1995. Epidemiology and control of malaria in the Federal Islamic Republic of Comoros. Sante 5 :368–371.

  • 2

    Parola P, Gazin P, Pradines B, Parzy D, Delmont J, Brouqui P, 2004. Marseilles: a surveillance site for malaria from the Comoros Islands. J Travel Med 11 :184–186.

    • Search Google Scholar
    • Export Citation
  • 3

    Tissot-Dupont H, Brouqui P, Faugere B, Raoult D, 1995. Prevalence of antibodies to Coxiella burnetii, Rickettsia conorii, and Rickettsia typhi in seven African countries. Clin Infect Dis 21 :1126–1133.

    • Search Google Scholar
    • Export Citation
  • 4

    Fishbein DB, Raoult D, 1992. A cluster of Coxiella burnetii infections associated with exposure to vaccinated goats and their unpasteurized dairy products. Am J Trop Med Hyg 47 :35–40.

    • Search Google Scholar
    • Export Citation
  • 5

    Brouqui P, Raoult D, Marrie T, 2003. Coxiella. Murray P, Baron R, Jorgensen JH, Pfaller M, Yolken R, eds. Manual of Clinical Microbiology. Washington, DC: American Society for Microbiology Press, 1030–1038.

  • 6

    Potasman I, Rzotkiewicz S, Pick N, Keysary A, 2000. Outbreak of Q fever following a safari trip. Clin Infect Dis 30 :214–215.

  • 7

    Parola P, Niang M, Badiaga S, Brouqui P, 2000. Acute Q fever in a patient returning from the tropics. Postgrad Med J 76 :113–114.

  • 8

    Adehossi E, Parola P, Foucault C, Delmont J, Brouqui P, Badiaga S, Ranque S, 2003. Three-day quinine-clindamycin treatment of uncomplicated falciparum malaria imported from the tropics (letter). Antimicrob Agents Chemother 47 :1173–1173.

    • Search Google Scholar
    • Export Citation
  • 9

    Parola P, Ranque S, Badiaga S, Niang M, Blin O, Charbit JJ, Delmont J, Brouqui P, 2001. Controlled trial of 3-day quinine-clindamycin treatment versus 7-day quinine treatment for adult travelers with uncomplicated falciparum malaria imported from the tropics. Antimicrob Agents Chemother 45 :932–935.

    • Search Google Scholar
    • Export Citation
  • 10

    Badiaga S, Barrau K, Brouqui P, Durant J, Malvy D, Janbon F, Bonnet E, Bosseray A, Sotto A, Peyramont D, Dydymski S, Cazorla C, Tolou H, Durant JP, Delmont J, 2003. Imported dengue in French university hospitals: a 6-year survey. J Travel Med 10 :286–289.

    • Search Google Scholar
    • Export Citation
  • 11

    Wongsrichanalai C, Murray CK, Gray M, Miller RS, Mcdaniel P, Liao WJ, Pickard AL, Magill AJ, 2003. Co-infection with malaria and leptospirosis. Am J Trop Med Hyg 68 :583–585.

    • Search Google Scholar
    • Export Citation
  • 12

    Graham SM, Hart CA, Molyneux EM, Walsh AL, Molyneux ME, 2000. Malaria and Salmonella infections: cause or coincidence? Trans R Soc Trop Med Hyg 94 :227–227.

    • Search Google Scholar
    • Export Citation
  • 13

    ter Kuile FO, Parise ME, Verhoeff FH, Udhayakumar V, Newman RD, Van Eijk AM, Rogerson SJ, Steketee RW, 2004. The burden of co-infection with human immunodeficiency virus type 1 and malaria in pregnant women in sub-Saharan Africa. Am J Trop Med Hyg 71 :41–54.

    • Search Google Scholar
    • Export Citation
  • 14

    Rolain JM, Gouriet F, Brouqui P, Larrey D, Janbon F, Vene S, Jarnestrom V, Raoult D, 2005. Concomitant or consecutive infection with Coxiella burnetii and tickborne diseases. Clin Infect Dis 40 :82–88.

    • Search Google Scholar
    • Export Citation
  • 15

    Niang M, Parola P, Tissot-Dupont H, Baidi L, Brouqui P, Raoult D, 1998. Prevalence of antibodies to Rickettsia conorii, Rickettsia africae, Rickettsia typhi and Coxiella burnetii in Mauritania. Eur J Epidemiol 14 :817–818.

    • Search Google Scholar
    • Export Citation
  • 16

    Okabayashi T, Hasebe F, Samui KL, Mweene AS, Pandey SG, Yanase T, Muramatsu Y, Ueno H, Morita C, 1999. Short report: Prevalence of antibodies against spotted fever, murine typhus, and Q fever rickettsiae in humans living in Zambia. Am J Trop Med Hyg 61 :70–72.

    • Search Google Scholar
    • Export Citation
  • 17

    Matthewman L, Kelly P, Hayter D, Downie S, Wray K, Bryson N, Rycroft A, Raoult D, 1997. Exposure of cats in southern Africa to Coxiella burnetii, the agent of Q fever. Eur J Epidemiol 13 :477–479.

    • Search Google Scholar
    • Export Citation
  • 18

    Boni M, Davoust B, Tissot-Dupont H, Raoult D, 1998. Survey of seroprevalence of Q fever in dogs in the southeast of France, French Guyana, Martinique, Senegal and the Ivory Coast. Vet Microbiol 64 :1–5.

    • Search Google Scholar
    • Export Citation
  • 19

    Naus CWA, Jones FM, Satti MZ, Joseph S, Riley EM, Kimani G, Mwatha JK, Kariuki CH, Ouma JH, Kabatereine NB, Vennervald BJ, Dunne DW, 2003. Serological responses among individuals in areas where both schistosomiasis and malaria are endemic: Cross-reactivity between Schistosoma mansoni and Plasmodium falciparum. J Infect Dis 187 :1272–1282.

    • Search Google Scholar
    • Export Citation
  • 20

    Dupont HT, Thirion X, Raoult D, 1994. Q fever serology: cutoff determination for microimmunofluorescence. Clin Diagn Lab Immunol 1 :189–196.

    • Search Google Scholar
    • Export Citation
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