Author:
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1
Masson PL, Heremans JF, 1971. Lactoferrin in milk from different species. Comp Biochem Physiol B 39 :119ā129.
-
2
Sanchez L, Calvo M, Brock JH, 1992. Biological role of lactoferrin. Arch Dis Child 67 :657ā661.
-
3
Farnaud S, Evans RW, 2003. Lactoferrin - a multifunctional protein with antimicrobial properties. Mol Immunol 40 :395ā405.
-
4
Tanaka T, Omata Y, Isamida T, Saito A, Shimazaki K, Yamauchi K, Suzuki N, 1998. Growth inhibitory effect of bovine lactoferrin to Toxoplasma gondii tachyzoites in murine macrophages: tyrosine phosphorylation in murine macrophages induced by bovine lactoferrin. J Vet Med Sci 60 :369ā371.
-
5
Tanaka T, Omata Y, Saito A, Shimazaki K, Igarashi I, Suzuki N, 1996. Growth inhibitory effect of bovine lactoferrin to Toxoplasma gondii parasites in murine somatic cells. J Vet Med Sci 58 :61ā65.
-
6
Lima MF, Beltz LA, Kierszenbaum F, 1988. Trypanosoma cruzi: a specific surface marker for the amastigote form. J Protozool 35 :108ā110.
-
7
Lima MF, Kierszenbaum F, 1985. Lactoferrin effects on phagocytic cell function. I. Increased uptake and killing of an intra-cellular parasite by murine macrophages and human monocytes. J Immunol 134 :4176ā4183.
-
8
Fritsch G, Sawatzki G, Treumer J, Jung A, Spira DT, 1987. Plasmodium falciparum: inhibition in vitro with lactoferrin, desferriferrithiocin, and desferricrocin. Exp Parasitol 63 :1ā9.
-
9
Mehlhorn H, Schein E, 1998. Redescription of Babesia equi Laveran, 1901 as Theileria equi. Parasitol Res 84 :467ā475.
-
10
BruĢing A, 1996. Equine piroplasmosis an update on diagnosis, treatment and prevention. Br Vet J 152 :139ā151.
-
11
Schein E, 1988. Equine babesiosis. Ristic M., ed. Babesiosis of Domestic Animals and Man. Boca Raton, FL: CRC Press, 197ā208.
-
12
BruĢng A, Phipps P, Posnett E, Canning EU, 1997. Monoclonal antibodies against Babesia caballi and Babesia equi and their application in serodiagnosis. Vet Parasitol 58 :11ā26.
-
13
de Waal DT, 2000. Global importance of piroplasmosis. J Protozool Res 10 :106ā127.
-
14
Friedhoff KT, Tenter AM, MuĢer I, 1990. Haemoparasites of equines: impact on the international trade of horses. Rev Sci Technol 9 :1187ā1194.
-
15
Avarazed A, Igarashi I, Kanemaru K, Hirumi K, Omata Y, Saito A, Oyamada T, Nagasawa H, Toyoda Y, Suzuki N, 1997. Improved in vitro cultivation of Babesia caballi. J Vet Med Sci 59 :479ā481.
-
16
Ikadai H, Martin MD, Nagasawa H, Fujisaki K, Suzuki N, Mikami T, Kudo N, Oyamada T, Igarashi I, 2001. Analysis of a growth-promoting factor for Babesia caballi cultivation. J Parasitol 87 :1484ā1486.
-
17
Zweygarth E, Just MC, de Waal DT, 1995. Continuous in vitro cultivation of erythrocytic stages of Babesia equi. Parasitol Res 81 :355ā358.
-
18
Law BA, Reiter B, 1977. The isolation and bacteriostatic properties of lactoferrin from bovine milk whey. J Dairy Res 44 :595ā599.
-
19
Litchfield JT, Wilcoxon F, 1949. A simplified method of evaluating dose-effect experiments. J Pharmacol Exp Ther 96 :99ā113.
-
20
Daniel WW, 1991. Biostatistics: A Foundation for Analysis in the Health Sciences. Fifth edition. New York: John Wiley & Sons.
-
21
Davidsson L, Kastenmayer P, Yuen M, LoĢnerdal B, Hurrell RF, 1994. Influence of lactoferrin on iron absorption from human milk in infants. Pediatr Res 35 :117ā124.
-
22
Wu HF, Monroe DM, Church FC, 1995. Characterization of the glycosaminoglycan-binding region of lactoferrin. Arch Biochem Biophys 317 :85ā92.
-
23
Zou S, Magura CE, Hurley WL, 1992. Heparin-binding properties of lactoferrin and lysozyme. Comp Biochem Physiol B103 :889ā895.
-
24
Sanchez-Lopez R, Haldar K, 1992. A transferrin-independent iron uptake activity in Plasmodium falciparum-infected and uninfected erythrocyte. Mol Biochem Parasitol 55 :9ā20.
-
25
Iron Panel of the International Committee for Standardization in Haematology, 1990. Revised recommendations for the measurements of the serum iron in human blood. Br J Haematol 75 :615ā616.
-
26
Arnold RR, Brewer M, Gauthier JJ, 1980. Bactericidal activity of human lactoferrin: sensitivity of a variety of microorganisms. Infect Immun 28 :893ā898.
-
27
Griffiths EA, Duffy LC, Schanbacher FL, Dryja D, Leavens A, Neiswander RL, Qiao H, DiRienzo D, Ogra P, 2003. In vitro growth responses of bifidobacteria and enteropathogens to bovine and human lactoferrin. Dig Dis Sci 48 :1324ā1332.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 18 | 18 | 4 |
| Full Text Views | 294 | 109 | 1 |
| PDF Downloads | 57 | 25 | 1 |
INHIBITORY EFFECT OF LACTOFERRIN ON IN VITRO GROWTH OF BABESIA CABALLI
HIROMI IKADAI
HIROMI IKADAI
Department of Veterinary Parasitology, and Department of Small Animal Medicine, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori, Japan; Dairy Science Laboratory, Graduate School of Agriculture, Hokkaido University, Sapporo, Hokkaido, Japan; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
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TETSUYA TANAKA
TETSUYA TANAKA
Department of Veterinary Parasitology, and Department of Small Animal Medicine, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori, Japan; Dairy Science Laboratory, Graduate School of Agriculture, Hokkaido University, Sapporo, Hokkaido, Japan; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
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NONA SHIBAHARA
NONA SHIBAHARA
Department of Veterinary Parasitology, and Department of Small Animal Medicine, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori, Japan; Dairy Science Laboratory, Graduate School of Agriculture, Hokkaido University, Sapporo, Hokkaido, Japan; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
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HIROKO TANAKA
HIROKO TANAKA
Department of Veterinary Parasitology, and Department of Small Animal Medicine, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori, Japan; Dairy Science Laboratory, Graduate School of Agriculture, Hokkaido University, Sapporo, Hokkaido, Japan; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
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AYA MATSUU
AYA MATSUU
Department of Veterinary Parasitology, and Department of Small Animal Medicine, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori, Japan; Dairy Science Laboratory, Graduate School of Agriculture, Hokkaido University, Sapporo, Hokkaido, Japan; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
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NOBORU KUDO
NOBORU KUDO
Department of Veterinary Parasitology, and Department of Small Animal Medicine, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori, Japan; Dairy Science Laboratory, Graduate School of Agriculture, Hokkaido University, Sapporo, Hokkaido, Japan; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
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KEI-ICHI SHIMAZAKI
KEI-ICHI SHIMAZAKI
Department of Veterinary Parasitology, and Department of Small Animal Medicine, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori, Japan; Dairy Science Laboratory, Graduate School of Agriculture, Hokkaido University, Sapporo, Hokkaido, Japan; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
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IKUO IGARASHI
IKUO IGARASHI
Department of Veterinary Parasitology, and Department of Small Animal Medicine, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori, Japan; Dairy Science Laboratory, Graduate School of Agriculture, Hokkaido University, Sapporo, Hokkaido, Japan; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
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TAKASHI OYAMADA
TAKASHI OYAMADA
Department of Veterinary Parasitology, and Department of Small Animal Medicine, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori, Japan; Dairy Science Laboratory, Graduate School of Agriculture, Hokkaido University, Sapporo, Hokkaido, Japan; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
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Lactoferrin (LF) is an important biologic molecule with many functions, one of which is antimicrobial defense. We evaluated the growth-inhibiting effects of four types of LF (native LF, Fe+3-bound [holo] LF, Fe+3-free [apo] LF, and LF hydrolyzate) on the in vitro growth of Babesia caballi and B. equi. The growth of B. caballi was significantly suppressed in media containing apo LF, but was not inhibited in media containing native LF, holo LF, or LF hydrolyzate. The growth of B. equi was not inhibited by media containing native LF, holo LF, or apo LF. These data indicate that apo LF had the strongest inhibitory effect on B. caballi. This may have been caused by inactivation or inhibition of a growth factor in the culture medium.
Author Notes
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
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-
1
Masson PL, Heremans JF, 1971. Lactoferrin in milk from different species. Comp Biochem Physiol B 39 :119ā129.
-
2
Sanchez L, Calvo M, Brock JH, 1992. Biological role of lactoferrin. Arch Dis Child 67 :657ā661.
-
3
Farnaud S, Evans RW, 2003. Lactoferrin - a multifunctional protein with antimicrobial properties. Mol Immunol 40 :395ā405.
-
4
Tanaka T, Omata Y, Isamida T, Saito A, Shimazaki K, Yamauchi K, Suzuki N, 1998. Growth inhibitory effect of bovine lactoferrin to Toxoplasma gondii tachyzoites in murine macrophages: tyrosine phosphorylation in murine macrophages induced by bovine lactoferrin. J Vet Med Sci 60 :369ā371.
-
5
Tanaka T, Omata Y, Saito A, Shimazaki K, Igarashi I, Suzuki N, 1996. Growth inhibitory effect of bovine lactoferrin to Toxoplasma gondii parasites in murine somatic cells. J Vet Med Sci 58 :61ā65.
-
6
Lima MF, Beltz LA, Kierszenbaum F, 1988. Trypanosoma cruzi: a specific surface marker for the amastigote form. J Protozool 35 :108ā110.
-
7
Lima MF, Kierszenbaum F, 1985. Lactoferrin effects on phagocytic cell function. I. Increased uptake and killing of an intra-cellular parasite by murine macrophages and human monocytes. J Immunol 134 :4176ā4183.
-
8
Fritsch G, Sawatzki G, Treumer J, Jung A, Spira DT, 1987. Plasmodium falciparum: inhibition in vitro with lactoferrin, desferriferrithiocin, and desferricrocin. Exp Parasitol 63 :1ā9.
-
9
Mehlhorn H, Schein E, 1998. Redescription of Babesia equi Laveran, 1901 as Theileria equi. Parasitol Res 84 :467ā475.
-
10
BruĢing A, 1996. Equine piroplasmosis an update on diagnosis, treatment and prevention. Br Vet J 152 :139ā151.
-
11
Schein E, 1988. Equine babesiosis. Ristic M., ed. Babesiosis of Domestic Animals and Man. Boca Raton, FL: CRC Press, 197ā208.
-
12
BruĢng A, Phipps P, Posnett E, Canning EU, 1997. Monoclonal antibodies against Babesia caballi and Babesia equi and their application in serodiagnosis. Vet Parasitol 58 :11ā26.
-
13
de Waal DT, 2000. Global importance of piroplasmosis. J Protozool Res 10 :106ā127.
-
14
Friedhoff KT, Tenter AM, MuĢer I, 1990. Haemoparasites of equines: impact on the international trade of horses. Rev Sci Technol 9 :1187ā1194.
-
15
Avarazed A, Igarashi I, Kanemaru K, Hirumi K, Omata Y, Saito A, Oyamada T, Nagasawa H, Toyoda Y, Suzuki N, 1997. Improved in vitro cultivation of Babesia caballi. J Vet Med Sci 59 :479ā481.
-
16
Ikadai H, Martin MD, Nagasawa H, Fujisaki K, Suzuki N, Mikami T, Kudo N, Oyamada T, Igarashi I, 2001. Analysis of a growth-promoting factor for Babesia caballi cultivation. J Parasitol 87 :1484ā1486.
-
17
Zweygarth E, Just MC, de Waal DT, 1995. Continuous in vitro cultivation of erythrocytic stages of Babesia equi. Parasitol Res 81 :355ā358.
-
18
Law BA, Reiter B, 1977. The isolation and bacteriostatic properties of lactoferrin from bovine milk whey. J Dairy Res 44 :595ā599.
-
19
Litchfield JT, Wilcoxon F, 1949. A simplified method of evaluating dose-effect experiments. J Pharmacol Exp Ther 96 :99ā113.
-
20
Daniel WW, 1991. Biostatistics: A Foundation for Analysis in the Health Sciences. Fifth edition. New York: John Wiley & Sons.
-
21
Davidsson L, Kastenmayer P, Yuen M, LoĢnerdal B, Hurrell RF, 1994. Influence of lactoferrin on iron absorption from human milk in infants. Pediatr Res 35 :117ā124.
-
22
Wu HF, Monroe DM, Church FC, 1995. Characterization of the glycosaminoglycan-binding region of lactoferrin. Arch Biochem Biophys 317 :85ā92.
-
23
Zou S, Magura CE, Hurley WL, 1992. Heparin-binding properties of lactoferrin and lysozyme. Comp Biochem Physiol B103 :889ā895.
-
24
Sanchez-Lopez R, Haldar K, 1992. A transferrin-independent iron uptake activity in Plasmodium falciparum-infected and uninfected erythrocyte. Mol Biochem Parasitol 55 :9ā20.
-
25
Iron Panel of the International Committee for Standardization in Haematology, 1990. Revised recommendations for the measurements of the serum iron in human blood. Br J Haematol 75 :615ā616.
-
26
Arnold RR, Brewer M, Gauthier JJ, 1980. Bactericidal activity of human lactoferrin: sensitivity of a variety of microorganisms. Infect Immun 28 :893ā898.
-
27
Griffiths EA, Duffy LC, Schanbacher FL, Dryja D, Leavens A, Neiswander RL, Qiao H, DiRienzo D, Ogra P, 2003. In vitro growth responses of bifidobacteria and enteropathogens to bovine and human lactoferrin. Dig Dis Sci 48 :1324ā1332.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 18 | 18 | 4 |
| Full Text Views | 294 | 109 | 1 |
| PDF Downloads | 57 | 25 | 1 |