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Reference Manager
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-
1
Currie BJ, 2003. Melioidosis: an important cause of pneumonia in residents of and travellers returned from endemic regions. Eur Respir J 22 :542–550.
-
3
Walsh AL, Wuthiekanun V, 1996. The laboratory diagnosis of melioidosis. Br J Biomed Sci 53 :249–253.
-
4
Currie BJ, Fisher DA, Howard DM, Burrow JN, Lo D, Selva-Nayagam S, Anstey NM, Huffam SE, Snelling PL, Marks PJ, Stephens DP, Lum GD, Jacups SP, Krause VL, 2000. Endemic melioidosis in tropical northern Australia: a 10-year prospective study and review of the literature. Clin Infect Dis 31 :981–986.
-
5
Chaowagul W, White NJ, Dance DA, Wattanagoon Y, Naigowit P, Davis TM, Looareesuwan S, Pitakwatchara N, 1989. Melioidosis: a major cause of community-acquired septicemia in northeastern Thailand. J Infect Dis 159 :890–899.
-
6
Mukhopadhyay A, Lee KH, Tambyah PA, 2004. Bacteraemic melioidosis pneumonia: impact on outcome, clinical and radiological features. J Infect 48 :334–338.
-
7
Cheng AC, Jacups SP, Anstey NM, Currie BJ, 2003. A proposed scoring system for predicting mortality in melioidosis. Trans R Soc Trop Med Hyg 97 :577–581.
-
8
Everett ED, Nelson RA, 1975. Pulmonary melioidosis. Observations in thirty-nine cases. Am Rev Respir Dis 112 :331–340.
-
9
Ip M, Osterberg LG, Chau PY, Raffin TA, 1995. Pulmonary melioidosis. Chest 108 :1420–1424.
-
10
Wuthiekanun V, Suputtamongkol Y, Simpson AJ, Kanaphun P, White NJ, 2001. Value of throat swab in diagnosis of melioidosis. J Clin Microbiol 39 :3801–3802.
-
11
Kanaphun P, Thirawattanasuk N, Suputtamongkol Y, Naigowit P, Dance DA, Smith MD, White NJ, 1993. Serology and carriage of Pseudomonas pseudomallei: a prospective study in 1000 hospitalized children in northeast Thailand. J Infect Dis 167 :230–233.
-
12
Sirisinha S, Anuntagool N, Dharakul T, Ekpo P, Wongratanacheewin S, Naigowit P, Petchclai B, Thamlikitkul V, Suputtamongkol Y, 2000. Recent developments in laboratory diagnosis of melioidosis. Acta Trop 74 :235–245.
-
13
Kunakorn M, Raksakait K, Sethaudom C, Sermswan RW, Dharakul T, 2000. Comparison of three PCR primer sets for diagnosis of septicemic melioidosis. Acta Trop 74 :247–251.
-
14
Walsh AL, Smith MD, Wuthiekanun V, Suputtamongkol Y, Desakorn V, Chaowagul W, White NJ, 1994. Immunofluorescence microscopy for the rapid diagnosis of melioidosis. J Clin Pathol 47 :377–379.
-
15
Wuthiekanun V, Desakorn V, Wongsuvan G, Amornchai P, Cheng AC, Maharjan B, Limmathurotsakul D, Chierakul W, White NJ, Day NP, Peacock SJ, 2005. Rapid immunofluorescence microscopy for diagnosis of melioidosis. Clin Diagn Lab Immunol 12 :555–556.
-
16
Nimmannit S, Malasit P, Susaengrat W, Ong-Aj-Yooth S, Vasuvattakul S, Pidetcha P, Shayakul C, Nilwarangkur S, 1996. Prevalence of endemic distal renal tubular acidosis and renal stone in the northeast of Thailand. Nephron 72 :604–610.
-
17
Barnes JL, Warner J, Melrose W, Durrheim D, Speare R, Reeder JC, Ketheesan N, 2004. Adaptive immunity in melioidosis: a possible role for T cells in determining outcome of infection with Burkholderia pseudomallei. Clin Immunol 113 :22–28.
-
18
Ketheesan N, Barnes JL, Ulett GC, VanGessel HJ, Norton RE, Hirst RG, LaBrooy JT, 2002. Demonstration of a cell-mediated immune response in melioidosis. J Infect Dis 186 :286–289.
| Past two years | Past Year | Past 30 Days | |
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| Abstract Views | 384 | 362 | 18 |
| Full Text Views | 220 | 2 | 0 |
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THE ROLE AND SIGNIFICANCE OF SPUTUM CULTURES IN THE DIAGNOSIS OF MELIOIDOSIS
DIANA HUIS IN ’T VELD
DIANA HUIS IN ’T VELD
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Menzies School of Health Research, Charles Darwin University and Northern Territory Clinical School, Flinders University, Darwin, Australia; Medical Department, Sappasithiprasong Hospital, Ubon Ratchathani, Thailand; Department of Internal Medicine and Infectious Diseases, St. George’s Hospital Medical School, London, United Kingdom; University Medical Centre Nijmegen, The Netherlands; Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom
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VANAPORN WUTHIEKANUN
VANAPORN WUTHIEKANUN
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Menzies School of Health Research, Charles Darwin University and Northern Territory Clinical School, Flinders University, Darwin, Australia; Medical Department, Sappasithiprasong Hospital, Ubon Ratchathani, Thailand; Department of Internal Medicine and Infectious Diseases, St. George’s Hospital Medical School, London, United Kingdom; University Medical Centre Nijmegen, The Netherlands; Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom
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ALLEN C. CHENG
ALLEN C. CHENG
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Menzies School of Health Research, Charles Darwin University and Northern Territory Clinical School, Flinders University, Darwin, Australia; Medical Department, Sappasithiprasong Hospital, Ubon Ratchathani, Thailand; Department of Internal Medicine and Infectious Diseases, St. George’s Hospital Medical School, London, United Kingdom; University Medical Centre Nijmegen, The Netherlands; Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom
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WIRONGRONG CHIERAKUL
WIRONGRONG CHIERAKUL
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Menzies School of Health Research, Charles Darwin University and Northern Territory Clinical School, Flinders University, Darwin, Australia; Medical Department, Sappasithiprasong Hospital, Ubon Ratchathani, Thailand; Department of Internal Medicine and Infectious Diseases, St. George’s Hospital Medical School, London, United Kingdom; University Medical Centre Nijmegen, The Netherlands; Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom
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WIPADA CHAOWAGUL
WIPADA CHAOWAGUL
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Menzies School of Health Research, Charles Darwin University and Northern Territory Clinical School, Flinders University, Darwin, Australia; Medical Department, Sappasithiprasong Hospital, Ubon Ratchathani, Thailand; Department of Internal Medicine and Infectious Diseases, St. George’s Hospital Medical School, London, United Kingdom; University Medical Centre Nijmegen, The Netherlands; Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom
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ANNEMARIE E. BROUWER
ANNEMARIE E. BROUWER
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Menzies School of Health Research, Charles Darwin University and Northern Territory Clinical School, Flinders University, Darwin, Australia; Medical Department, Sappasithiprasong Hospital, Ubon Ratchathani, Thailand; Department of Internal Medicine and Infectious Diseases, St. George’s Hospital Medical School, London, United Kingdom; University Medical Centre Nijmegen, The Netherlands; Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom
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NICHOLAS J. WHITE
NICHOLAS J. WHITE
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Menzies School of Health Research, Charles Darwin University and Northern Territory Clinical School, Flinders University, Darwin, Australia; Medical Department, Sappasithiprasong Hospital, Ubon Ratchathani, Thailand; Department of Internal Medicine and Infectious Diseases, St. George’s Hospital Medical School, London, United Kingdom; University Medical Centre Nijmegen, The Netherlands; Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom
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NICHOLAS P. J. DAY
NICHOLAS P. J. DAY
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Menzies School of Health Research, Charles Darwin University and Northern Territory Clinical School, Flinders University, Darwin, Australia; Medical Department, Sappasithiprasong Hospital, Ubon Ratchathani, Thailand; Department of Internal Medicine and Infectious Diseases, St. George’s Hospital Medical School, London, United Kingdom; University Medical Centre Nijmegen, The Netherlands; Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom
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SHARON J. PEACOCK
SHARON J. PEACOCK
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Menzies School of Health Research, Charles Darwin University and Northern Territory Clinical School, Flinders University, Darwin, Australia; Medical Department, Sappasithiprasong Hospital, Ubon Ratchathani, Thailand; Department of Internal Medicine and Infectious Diseases, St. George’s Hospital Medical School, London, United Kingdom; University Medical Centre Nijmegen, The Netherlands; Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom
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Pneumonia is a common manifestation of melioidosis, the disease caused by Burkholderia pseudomallei. In this study, we defined the prognostic significance of a positive sputum culture. A total of 712 patients presenting to Sappasithiprasong Hospital, Ubon Ratchathani, Thailand, with melioidosis between January 1992 and December 2002 had a sputum culture performed during admission, which was positive for B. pseudomallei in 444 patients (62%). The median duration of sputum positivity was 9 days (range, 1 to 49 days). Sputum cultures were negative in 32% of patients with radiologic changes suggestive of pulmonary involvement. Overall in-hospital mortality was 48%. A positive sputum culture was associated with mortality (adjusted OR 2.8, 95% CI: 1.9, 4.0; P < 0.001). This was independent of renal disease, a prior history of melioidosis, positive blood cultures, and other potential confounders. The presence of B. pseudomallei in the sputum of patients with melioidosis is associated with a poorer prognosis.
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ProCite
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-
1
Currie BJ, 2003. Melioidosis: an important cause of pneumonia in residents of and travellers returned from endemic regions. Eur Respir J 22 :542–550.
-
3
Walsh AL, Wuthiekanun V, 1996. The laboratory diagnosis of melioidosis. Br J Biomed Sci 53 :249–253.
-
4
Currie BJ, Fisher DA, Howard DM, Burrow JN, Lo D, Selva-Nayagam S, Anstey NM, Huffam SE, Snelling PL, Marks PJ, Stephens DP, Lum GD, Jacups SP, Krause VL, 2000. Endemic melioidosis in tropical northern Australia: a 10-year prospective study and review of the literature. Clin Infect Dis 31 :981–986.
-
5
Chaowagul W, White NJ, Dance DA, Wattanagoon Y, Naigowit P, Davis TM, Looareesuwan S, Pitakwatchara N, 1989. Melioidosis: a major cause of community-acquired septicemia in northeastern Thailand. J Infect Dis 159 :890–899.
-
6
Mukhopadhyay A, Lee KH, Tambyah PA, 2004. Bacteraemic melioidosis pneumonia: impact on outcome, clinical and radiological features. J Infect 48 :334–338.
-
7
Cheng AC, Jacups SP, Anstey NM, Currie BJ, 2003. A proposed scoring system for predicting mortality in melioidosis. Trans R Soc Trop Med Hyg 97 :577–581.
-
8
Everett ED, Nelson RA, 1975. Pulmonary melioidosis. Observations in thirty-nine cases. Am Rev Respir Dis 112 :331–340.
-
9
Ip M, Osterberg LG, Chau PY, Raffin TA, 1995. Pulmonary melioidosis. Chest 108 :1420–1424.
-
10
Wuthiekanun V, Suputtamongkol Y, Simpson AJ, Kanaphun P, White NJ, 2001. Value of throat swab in diagnosis of melioidosis. J Clin Microbiol 39 :3801–3802.
-
11
Kanaphun P, Thirawattanasuk N, Suputtamongkol Y, Naigowit P, Dance DA, Smith MD, White NJ, 1993. Serology and carriage of Pseudomonas pseudomallei: a prospective study in 1000 hospitalized children in northeast Thailand. J Infect Dis 167 :230–233.
-
12
Sirisinha S, Anuntagool N, Dharakul T, Ekpo P, Wongratanacheewin S, Naigowit P, Petchclai B, Thamlikitkul V, Suputtamongkol Y, 2000. Recent developments in laboratory diagnosis of melioidosis. Acta Trop 74 :235–245.
-
13
Kunakorn M, Raksakait K, Sethaudom C, Sermswan RW, Dharakul T, 2000. Comparison of three PCR primer sets for diagnosis of septicemic melioidosis. Acta Trop 74 :247–251.
-
14
Walsh AL, Smith MD, Wuthiekanun V, Suputtamongkol Y, Desakorn V, Chaowagul W, White NJ, 1994. Immunofluorescence microscopy for the rapid diagnosis of melioidosis. J Clin Pathol 47 :377–379.
-
15
Wuthiekanun V, Desakorn V, Wongsuvan G, Amornchai P, Cheng AC, Maharjan B, Limmathurotsakul D, Chierakul W, White NJ, Day NP, Peacock SJ, 2005. Rapid immunofluorescence microscopy for diagnosis of melioidosis. Clin Diagn Lab Immunol 12 :555–556.
-
16
Nimmannit S, Malasit P, Susaengrat W, Ong-Aj-Yooth S, Vasuvattakul S, Pidetcha P, Shayakul C, Nilwarangkur S, 1996. Prevalence of endemic distal renal tubular acidosis and renal stone in the northeast of Thailand. Nephron 72 :604–610.
-
17
Barnes JL, Warner J, Melrose W, Durrheim D, Speare R, Reeder JC, Ketheesan N, 2004. Adaptive immunity in melioidosis: a possible role for T cells in determining outcome of infection with Burkholderia pseudomallei. Clin Immunol 113 :22–28.
-
18
Ketheesan N, Barnes JL, Ulett GC, VanGessel HJ, Norton RE, Hirst RG, LaBrooy JT, 2002. Demonstration of a cell-mediated immune response in melioidosis. J Infect Dis 186 :286–289.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 384 | 362 | 18 |
| Full Text Views | 220 | 2 | 0 |
| PDF Downloads | 54 | 2 | 0 |