Mendis K, Sina BJ, Marchesini P, Carter R, 2001. The neglected burden of Plasmodium vivax malaria. Am J Trop Med Hyg 64 (Suppl):97–106.
Carter R, Mendis KN, 2002. Evolutionary and historical aspects of the burden of malaria. Clin Microbiol Rev 15 :564–594.
Miller LH, McAuliffe FM, Johnson JG, 1979. Invasion of erythrocytes by malaria merozoites. Prog Clin Biol Res 30 :497–502.
Wertheimer SP, Barnwell JW, 1989. Plasmodium vivax interaction with the human Duffy blood group glycoprotein: identification of a parasite receptor-like protein. Exp Parasitol 69 :340–350.
Fang XD, Kaslow DC, Adams JH, Miller LH, 1991. Cloning of the Plasmodium vivax Duffy receptor. Mol Biochem Parasitol 44 :125–132.
Adams JH, Fang X, Kaslow DC, Miller LH, 1992. Identification of a cryptic intron in the Plasmodium vivax Duffy binding protein gene. Mol Biochem Parasitol 56 :181–183.
Horuk R, Chitnis CE, Darbonne WC, Colby TJ, Rybicki A, Hadley TJ, Miller LH, 1993. A receptor for the malarial parasite Plasmodium vivax: the erythrocyte chemokine receptor. Science 261 :1182–1184.
Miller LH, Mason SJ, Clyde DF, McGinniss MH, 1976. The resistance factor to Plasmodium vivax in blacks. The Duffy-blood-group genotype, FyFy. N Engl J Med 295 :302–304.
Barnwell JW, Wertheimer SP, 1989. Plasmodium vivax: merozoite antigens, the Duffy blood group, and erythrocyte invasion. Prog Clin Biol Res 313 :1–11.
Adams JH, Hudson DE, Torii M, Ward GE, Wellems TE, Aikawa M, Miller LH, 1990. The Duffy receptor family of Plasmodium knowlesi is located within the micronemes of invasive malaria merozoites. Cell 63 :141–153.
Fraser T, Michon P, Barnwell JW, Noe AR, Al-Yaman F, Kaslow DC, Adams JH, 1997. Expression and serologic activity of a soluble recombinant Plasmodium vivax Duffy binding protein. Infect Immun 65 :2772–2777.
Michon PA, Arevalo-Herrera M, Fraser T, Herrera S, Adams JH, 1998. Serologic responses to recombinant Plasmodium vivax Duffy binding protein in a Colombian village. Am J Trop Med Hyg 59 :597–599.
Suh IB, Choi HK, Lee SW, Woo SK, Kang HY, Won YD, Cho M, Lim CS, 2003. Reactivity of sera from cases of Plasmodium vivax malaria towards three recombinant antigens based on the surface proteins of the parasite. Ann Trop Med Parasitol 97 :481–487.
Xainli J, Cole-Tobian JL, Baisor M, Kastens W, Bockarie M, Yazdani SS, Chitnis CE, Adams JH, King CL, 2003. Epitope-specific humoral immunity to Plasmodium vivax Duffy binding protein. Infect Immun 71 :2508–2515.
Camargo LM, Ferreira MU, Krieger H, De Camargo EP, Da Silva LP, 1994. Unstable hypoendemic malaria in Rondonia (western Amazon region, Brazil): epidemic outbreaks and work-associated incidence in an agro-industrial rural settlement. Am J Trop Med Hyg 51 :16–25.
Singer BH, de Castro MC, 2001. Agricultural colonization and malaria on the Amazon frontier. Ann N Y Acad Sci 954 :184–222.
Carvalho LH, Fontes CJ, Fernandes AA, Marinuzzi HC, Krettli AU, 1997. Cross-reactive cellular immune response to circum-sporozoite proteins of Plasmodium vivax and P. falciparum in malaria-exposed individuals. Parasite Immunol 19 :47–59.
Carvalho LH, Fontes CJ, Krettli AU, 1999. Cellular responses to Plasmodium falciparum major surface antigens and their relationship to human activities associated with malaria transmission. Am J Trop Med Hyg 60 :674–679.
Braga EM, Barros RM, Reis TA, Fontes CJ, Morais CG, Martins MS, Krettli AU, 2002. Association of the IgG response to Plasmodium falciparum merozoite protein (C-terminal 19 kD) with clinical immunity to malaria in the Brazilian Amazon region. Am J Trop Med Hyg 66 :461–466.
Braga EM, Carvalho LH, Fontes CJ, Krettli AU, 2002. Low cellular response in vitro among subjects with long-term exposure to malaria transmission in Brazilian endemic areas. Am J Trop Med Hyg 66 :299–303.
Souto FJ, Fontes CJ, Gaspar AM, 2001. Prevalence of hepatitis B and C virus markers among malaria-exposed gold miners in Brazilian Amazon. Mem Inst Oswaldo Cruz 96 :751–755.
Smith JA, 2002. Electroelution of proteins from stained gels. Coligan JE, Kruisbeek, AM, Margulies DH, Shevach EM, Strober W, eds. Current Protocols in Immunology. New York: John Wiley & Sons, 8.8.1–8.8.5.
Cunha MG, Rodrigues MM, Soares IS, 2001. Comparison of the immunogenic properties of recombinant proteins representing the Plasmodium vivax vaccine candidate MSP1(19) expressed in distinct bacterial vectors. Vaccine 20 :385–396.
Soares IS, Barnwell JW, Ferreira MU, Gomes Da Cunha M, Laurino JP, Castilho BA, Rodrigues MM, 1999. A Plasmodium vivax vaccine candidate displays limited allele polymorphism, which does not restrict recognition by antibodies. Mol Med 5 :459–470.
Michon P, Fraser T, Adams JH, 2000. Naturally acquired and vaccine-elicited antibodies block erythrocyte cytoadherence of the Plasmodium vivax Duffy binding protein. Infect Immun 68 :3164–3171.
Baird JK, 1998. Age-dependent characteristics of protection v. susceptibility to Plasmodium falciparum. Ann Trop Med Parasitol 92 :367–390.
Hudson Keenihan SN, Ratiwayanto S, Soebianto S, Krisin, Marwoto H, Krishnegowda G, Gowda DC, Bangs MJ, Fryauff DJ, Richie TL, Kumar S, Baird JK, 2003. Age-dependent impairment of IgG responses to glycosylphosphatidylinositol with equal exposure to Plasmodium falciparum among Javanese migrants to Papua, Indonesia. Am J Trop Med Hyg 69 :36–41.
Pasay MC, Cheng Q, Rzepczyk C, Saul A, 1995. Dimorphism of the C terminus of the Plasmodium vivax merozoite surface protein 1. Mol Biochem Parasitol 70 :217–219.
Putaporntip C, Jongwutiwes S, Seethamchai S, Kanbara H, Tanabe K, 2000. Intragenic recombination in the 3′ portion of the merozoite surface protein 1 gene of Plasmodium vivax. Mol Biochem Parasitol 109 :111–119.
Braga EM, Fontes CJ, Krettli AU, 1998. Persistence of humoral response against sporozoite and blood-stage malaria antigens 7 years after a brief exposure to Plasmodium vivax. J Infect Dis 177 :1132–1135.
Soares IS, da Cunha MG, Silva MN, Souza JM, Del Portillo HA, Rodrigues MM, 1999. Longevity of naturally acquired antibody responses to the N- and C-terminal regions of Plasmodium vivax merozoite surface protein 1. Am J Trop Med Hyg 60 :357–363.
Park JW, Moon SH, Yeom JS, Lim KJ, Sohn MJ, Jung WC, Cho YJ, Jeon KW, Ju W, Ki CS, Oh MD, Choe K, 2001. Naturally acquired antibody responses to the C-terminal region of merozoite surface protein 1 of Plasmodium vivax in Korea. Clin Diagn Lab Immunol 8 :14–20.
Camargo EP, Alves F, Pereira da Silva LH, 1999. Symptomless Plasmodium vivax infections in native Amazonians. Lancet 353 :1415–1416.
Alves FP, Durlacher RR, Menezes MJ, Krieger H, Silva LH, Camargo EP, 2002. High prevalence of asymptomatic Plasmodium vivax and Plasmodium falciparum infections in native Amazonian populations. Am J Trop Med Hyg 66 :641–648.
Michon P, Woolley I, Wood EM, Kastens W, Zimmerman PA, Adams JH, 2001. Duffy-null promoter heterozygosity reduces DARC expression and abrogates adhesion of the P. vivax ligand required for blood-stage infection. FEBS Lett 495 :111–114.
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Plasmodium vivax Duffy binding protein (DBP) is functionally important in the erythrocyte invasion process and provides a logical target for vaccine-mediated immunity. In the current study, we demonstrated that DBP is naturally immunogenic in different populations of the Brazilian Amazon, and the proportions of DBP IgG positive subjects increased with exposure to malaria, reaching a peak in those subjects with long-term exposure (> 15 years) in the Amazon area. This profile of antibody response was significantly different from the one observed for the P. vivax merozoite surface protein 1 (MSP119), which was relatively uniform in areas with markedly different levels of malaria transmission. In a small sample of adults with symptomless P. vivax infection, we could not detect any significant correlation between antibodies against these P. vivax proteins and asymptomatic infection. Our study provided an additional insight by demonstrating cumulative exposure as a determinant that acts independently of host age in generation of anti-DBP IgG response.
Mendis K, Sina BJ, Marchesini P, Carter R, 2001. The neglected burden of Plasmodium vivax malaria. Am J Trop Med Hyg 64 (Suppl):97–106.
Carter R, Mendis KN, 2002. Evolutionary and historical aspects of the burden of malaria. Clin Microbiol Rev 15 :564–594.
Miller LH, McAuliffe FM, Johnson JG, 1979. Invasion of erythrocytes by malaria merozoites. Prog Clin Biol Res 30 :497–502.
Wertheimer SP, Barnwell JW, 1989. Plasmodium vivax interaction with the human Duffy blood group glycoprotein: identification of a parasite receptor-like protein. Exp Parasitol 69 :340–350.
Fang XD, Kaslow DC, Adams JH, Miller LH, 1991. Cloning of the Plasmodium vivax Duffy receptor. Mol Biochem Parasitol 44 :125–132.
Adams JH, Fang X, Kaslow DC, Miller LH, 1992. Identification of a cryptic intron in the Plasmodium vivax Duffy binding protein gene. Mol Biochem Parasitol 56 :181–183.
Horuk R, Chitnis CE, Darbonne WC, Colby TJ, Rybicki A, Hadley TJ, Miller LH, 1993. A receptor for the malarial parasite Plasmodium vivax: the erythrocyte chemokine receptor. Science 261 :1182–1184.
Miller LH, Mason SJ, Clyde DF, McGinniss MH, 1976. The resistance factor to Plasmodium vivax in blacks. The Duffy-blood-group genotype, FyFy. N Engl J Med 295 :302–304.
Barnwell JW, Wertheimer SP, 1989. Plasmodium vivax: merozoite antigens, the Duffy blood group, and erythrocyte invasion. Prog Clin Biol Res 313 :1–11.
Adams JH, Hudson DE, Torii M, Ward GE, Wellems TE, Aikawa M, Miller LH, 1990. The Duffy receptor family of Plasmodium knowlesi is located within the micronemes of invasive malaria merozoites. Cell 63 :141–153.
Fraser T, Michon P, Barnwell JW, Noe AR, Al-Yaman F, Kaslow DC, Adams JH, 1997. Expression and serologic activity of a soluble recombinant Plasmodium vivax Duffy binding protein. Infect Immun 65 :2772–2777.
Michon PA, Arevalo-Herrera M, Fraser T, Herrera S, Adams JH, 1998. Serologic responses to recombinant Plasmodium vivax Duffy binding protein in a Colombian village. Am J Trop Med Hyg 59 :597–599.
Suh IB, Choi HK, Lee SW, Woo SK, Kang HY, Won YD, Cho M, Lim CS, 2003. Reactivity of sera from cases of Plasmodium vivax malaria towards three recombinant antigens based on the surface proteins of the parasite. Ann Trop Med Parasitol 97 :481–487.
Xainli J, Cole-Tobian JL, Baisor M, Kastens W, Bockarie M, Yazdani SS, Chitnis CE, Adams JH, King CL, 2003. Epitope-specific humoral immunity to Plasmodium vivax Duffy binding protein. Infect Immun 71 :2508–2515.
Camargo LM, Ferreira MU, Krieger H, De Camargo EP, Da Silva LP, 1994. Unstable hypoendemic malaria in Rondonia (western Amazon region, Brazil): epidemic outbreaks and work-associated incidence in an agro-industrial rural settlement. Am J Trop Med Hyg 51 :16–25.
Singer BH, de Castro MC, 2001. Agricultural colonization and malaria on the Amazon frontier. Ann N Y Acad Sci 954 :184–222.
Carvalho LH, Fontes CJ, Fernandes AA, Marinuzzi HC, Krettli AU, 1997. Cross-reactive cellular immune response to circum-sporozoite proteins of Plasmodium vivax and P. falciparum in malaria-exposed individuals. Parasite Immunol 19 :47–59.
Carvalho LH, Fontes CJ, Krettli AU, 1999. Cellular responses to Plasmodium falciparum major surface antigens and their relationship to human activities associated with malaria transmission. Am J Trop Med Hyg 60 :674–679.
Braga EM, Barros RM, Reis TA, Fontes CJ, Morais CG, Martins MS, Krettli AU, 2002. Association of the IgG response to Plasmodium falciparum merozoite protein (C-terminal 19 kD) with clinical immunity to malaria in the Brazilian Amazon region. Am J Trop Med Hyg 66 :461–466.
Braga EM, Carvalho LH, Fontes CJ, Krettli AU, 2002. Low cellular response in vitro among subjects with long-term exposure to malaria transmission in Brazilian endemic areas. Am J Trop Med Hyg 66 :299–303.
Souto FJ, Fontes CJ, Gaspar AM, 2001. Prevalence of hepatitis B and C virus markers among malaria-exposed gold miners in Brazilian Amazon. Mem Inst Oswaldo Cruz 96 :751–755.
Smith JA, 2002. Electroelution of proteins from stained gels. Coligan JE, Kruisbeek, AM, Margulies DH, Shevach EM, Strober W, eds. Current Protocols in Immunology. New York: John Wiley & Sons, 8.8.1–8.8.5.
Cunha MG, Rodrigues MM, Soares IS, 2001. Comparison of the immunogenic properties of recombinant proteins representing the Plasmodium vivax vaccine candidate MSP1(19) expressed in distinct bacterial vectors. Vaccine 20 :385–396.
Soares IS, Barnwell JW, Ferreira MU, Gomes Da Cunha M, Laurino JP, Castilho BA, Rodrigues MM, 1999. A Plasmodium vivax vaccine candidate displays limited allele polymorphism, which does not restrict recognition by antibodies. Mol Med 5 :459–470.
Michon P, Fraser T, Adams JH, 2000. Naturally acquired and vaccine-elicited antibodies block erythrocyte cytoadherence of the Plasmodium vivax Duffy binding protein. Infect Immun 68 :3164–3171.
Baird JK, 1998. Age-dependent characteristics of protection v. susceptibility to Plasmodium falciparum. Ann Trop Med Parasitol 92 :367–390.
Hudson Keenihan SN, Ratiwayanto S, Soebianto S, Krisin, Marwoto H, Krishnegowda G, Gowda DC, Bangs MJ, Fryauff DJ, Richie TL, Kumar S, Baird JK, 2003. Age-dependent impairment of IgG responses to glycosylphosphatidylinositol with equal exposure to Plasmodium falciparum among Javanese migrants to Papua, Indonesia. Am J Trop Med Hyg 69 :36–41.
Pasay MC, Cheng Q, Rzepczyk C, Saul A, 1995. Dimorphism of the C terminus of the Plasmodium vivax merozoite surface protein 1. Mol Biochem Parasitol 70 :217–219.
Putaporntip C, Jongwutiwes S, Seethamchai S, Kanbara H, Tanabe K, 2000. Intragenic recombination in the 3′ portion of the merozoite surface protein 1 gene of Plasmodium vivax. Mol Biochem Parasitol 109 :111–119.
Braga EM, Fontes CJ, Krettli AU, 1998. Persistence of humoral response against sporozoite and blood-stage malaria antigens 7 years after a brief exposure to Plasmodium vivax. J Infect Dis 177 :1132–1135.
Soares IS, da Cunha MG, Silva MN, Souza JM, Del Portillo HA, Rodrigues MM, 1999. Longevity of naturally acquired antibody responses to the N- and C-terminal regions of Plasmodium vivax merozoite surface protein 1. Am J Trop Med Hyg 60 :357–363.
Park JW, Moon SH, Yeom JS, Lim KJ, Sohn MJ, Jung WC, Cho YJ, Jeon KW, Ju W, Ki CS, Oh MD, Choe K, 2001. Naturally acquired antibody responses to the C-terminal region of merozoite surface protein 1 of Plasmodium vivax in Korea. Clin Diagn Lab Immunol 8 :14–20.
Camargo EP, Alves F, Pereira da Silva LH, 1999. Symptomless Plasmodium vivax infections in native Amazonians. Lancet 353 :1415–1416.
Alves FP, Durlacher RR, Menezes MJ, Krieger H, Silva LH, Camargo EP, 2002. High prevalence of asymptomatic Plasmodium vivax and Plasmodium falciparum infections in native Amazonian populations. Am J Trop Med Hyg 66 :641–648.
Michon P, Woolley I, Wood EM, Kastens W, Zimmerman PA, Adams JH, 2001. Duffy-null promoter heterozygosity reduces DARC expression and abrogates adhesion of the P. vivax ligand required for blood-stage infection. FEBS Lett 495 :111–114.
Past two years | Past Year | Past 30 Days | |
---|---|---|---|
Abstract Views | 243 | 202 | 20 |
Full Text Views | 234 | 6 | 4 |
PDF Downloads | 58 | 6 | 4 |