HUMAN BRAIN ABSCESS DUE TO A TETRA-ACETABULATE PLEROCERCOID METACESTODE (CYCLOPHYLLIDEA)

YVES J. F. GARIN Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Parasitology, Faculty of Pharmacy, University of Valencia, Spain; Service de Neurologie, Service de Neuro-chirurgie, and Service de Radiologie, Fondation Rothschild, Paris, France; Service d’Anatomie et Cytologie Pathologiques, Hôpital Lariboisière, U.F.R. Lariboisière, Université Paris VII, France; Department of Zoology, The National History Museum, London, UK; Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Biology, Berry College, Mount Berry, Georgia

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MARIA-TERESA GALÁN-PUCHADES Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Parasitology, Faculty of Pharmacy, University of Valencia, Spain; Service de Neurologie, Service de Neuro-chirurgie, and Service de Radiologie, Fondation Rothschild, Paris, France; Service d’Anatomie et Cytologie Pathologiques, Hôpital Lariboisière, U.F.R. Lariboisière, Université Paris VII, France; Department of Zoology, The National History Museum, London, UK; Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Biology, Berry College, Mount Berry, Georgia

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ANTOINE MOULIGNIER Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Parasitology, Faculty of Pharmacy, University of Valencia, Spain; Service de Neurologie, Service de Neuro-chirurgie, and Service de Radiologie, Fondation Rothschild, Paris, France; Service d’Anatomie et Cytologie Pathologiques, Hôpital Lariboisière, U.F.R. Lariboisière, Université Paris VII, France; Department of Zoology, The National History Museum, London, UK; Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Biology, Berry College, Mount Berry, Georgia

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GILLES ROBERT Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Parasitology, Faculty of Pharmacy, University of Valencia, Spain; Service de Neurologie, Service de Neuro-chirurgie, and Service de Radiologie, Fondation Rothschild, Paris, France; Service d’Anatomie et Cytologie Pathologiques, Hôpital Lariboisière, U.F.R. Lariboisière, Université Paris VII, France; Department of Zoology, The National History Museum, London, UK; Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Biology, Berry College, Mount Berry, Georgia

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FRANÇOISE HÉRAN Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Parasitology, Faculty of Pharmacy, University of Valencia, Spain; Service de Neurologie, Service de Neuro-chirurgie, and Service de Radiologie, Fondation Rothschild, Paris, France; Service d’Anatomie et Cytologie Pathologiques, Hôpital Lariboisière, U.F.R. Lariboisière, Université Paris VII, France; Department of Zoology, The National History Museum, London, UK; Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Biology, Berry College, Mount Berry, Georgia

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MARC POLIVKA Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Parasitology, Faculty of Pharmacy, University of Valencia, Spain; Service de Neurologie, Service de Neuro-chirurgie, and Service de Radiologie, Fondation Rothschild, Paris, France; Service d’Anatomie et Cytologie Pathologiques, Hôpital Lariboisière, U.F.R. Lariboisière, Université Paris VII, France; Department of Zoology, The National History Museum, London, UK; Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Biology, Berry College, Mount Berry, Georgia

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PETE D. OLSON Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Parasitology, Faculty of Pharmacy, University of Valencia, Spain; Service de Neurologie, Service de Neuro-chirurgie, and Service de Radiologie, Fondation Rothschild, Paris, France; Service d’Anatomie et Cytologie Pathologiques, Hôpital Lariboisière, U.F.R. Lariboisière, Université Paris VII, France; Department of Zoology, The National History Museum, London, UK; Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Biology, Berry College, Mount Berry, Georgia

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FRÉDÉRIC LORENZO Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Parasitology, Faculty of Pharmacy, University of Valencia, Spain; Service de Neurologie, Service de Neuro-chirurgie, and Service de Radiologie, Fondation Rothschild, Paris, France; Service d’Anatomie et Cytologie Pathologiques, Hôpital Lariboisière, U.F.R. Lariboisière, Université Paris VII, France; Department of Zoology, The National History Museum, London, UK; Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Biology, Berry College, Mount Berry, Georgia

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FRANCIS DEROUIN Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Parasitology, Faculty of Pharmacy, University of Valencia, Spain; Service de Neurologie, Service de Neuro-chirurgie, and Service de Radiologie, Fondation Rothschild, Paris, France; Service d’Anatomie et Cytologie Pathologiques, Hôpital Lariboisière, U.F.R. Lariboisière, Université Paris VII, France; Department of Zoology, The National History Museum, London, UK; Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Biology, Berry College, Mount Berry, Georgia

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DAVID BRUCE CONN Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Parasitology, Faculty of Pharmacy, University of Valencia, Spain; Service de Neurologie, Service de Neuro-chirurgie, and Service de Radiologie, Fondation Rothschild, Paris, France; Service d’Anatomie et Cytologie Pathologiques, Hôpital Lariboisière, U.F.R. Lariboisière, Université Paris VII, France; Department of Zoology, The National History Museum, London, UK; Laboratoire de Parasitologie-Mycologie, Hôpital Saint Louis, U.F.R. Lariboisière, Université Paris VII, France; Department of Biology, Berry College, Mount Berry, Georgia

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DOI:
https://doi.org/10.4269/ajtmh.2005.72.513
Volume/Issue:
Volume 72: Issue 5
Page(s):
513–517
Restricted access
Get Permissions

A 38-year-old man living near Phnom Penh (Cambodia) was admitted to a hospital in Paris in June 2001 for a single episode of a generalized grand mal seizure. This episode was preceded by a 9-month history of headaches. Magnetic resonance imaging (MRI) of the head revealed a rounded lesion immediately ahead of the left central sulcus. The resected lesion was about 20 mm in diameter. Histologic examination revealed an elongated but unsegmented metacestode at the center of the lesion. Polymerase chain reaction (PCR) analysis was inconclusive due to formalin-based histologic processing of the tissue. Morphologic analysis based on the histologic sections revealed that the metacestode was a tetra-acetabulate plerocercoid of the order Cyclophyllidea, with a distinct rostellum and pseudosegmentation of the dorsoventrally flattened hindbody. This is the first report of a tetra-acetabulate plerocercoid from a human host and the first report of any cyclophyllidean plerocercoid from the human brain. After 6 weeks, the patient was asymptomatic, neurologic examination was normal, and the brain MRI showed only surgical cavitation. The patient returned to Cambodia.

Author Notes

Reprint requests: Yves J. L. Garin, Laboratoire de Parasitologic-Mycologie, 15 rue de l’Ecole de Médecine, 75006, Paris, France.
Copyright:
Copyright 2005 The American Society of Tropical Medicine 2005
Received:
20 May 2004
|
Accepted:
13 Sep 2004
|
Published Online:
May 2005
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
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