SIMPLE CLINICAL MANIFESTATIONS OF GENITAL SCHISTOSOMA HAEMATOBIUM INFECTION IN RURAL ZIMBABWEAN WOMEN

EYRUN FLOERECKE KJETLAND Centre for Imported and Tropical Diseases, Department of Infectious Diseases, Ullevaal University Hospital, Oslo, Norway; College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe; Blair Research Institute, Harare, Zimbabwe; Biomedical Research and Training Institute, Harare, Zimbabwe; Department of Epidemiology, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark; Research Unit, Sorlandet Hospital/Department of Health and Sports, Agder University College, Kristiansand, Norway

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PATRICIA D. NDHLOVU Centre for Imported and Tropical Diseases, Department of Infectious Diseases, Ullevaal University Hospital, Oslo, Norway; College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe; Blair Research Institute, Harare, Zimbabwe; Biomedical Research and Training Institute, Harare, Zimbabwe; Department of Epidemiology, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark; Research Unit, Sorlandet Hospital/Department of Health and Sports, Agder University College, Kristiansand, Norway

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TAKAFIRA MDULUZA Centre for Imported and Tropical Diseases, Department of Infectious Diseases, Ullevaal University Hospital, Oslo, Norway; College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe; Blair Research Institute, Harare, Zimbabwe; Biomedical Research and Training Institute, Harare, Zimbabwe; Department of Epidemiology, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark; Research Unit, Sorlandet Hospital/Department of Health and Sports, Agder University College, Kristiansand, Norway

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EXENEVIA GOMO Centre for Imported and Tropical Diseases, Department of Infectious Diseases, Ullevaal University Hospital, Oslo, Norway; College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe; Blair Research Institute, Harare, Zimbabwe; Biomedical Research and Training Institute, Harare, Zimbabwe; Department of Epidemiology, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark; Research Unit, Sorlandet Hospital/Department of Health and Sports, Agder University College, Kristiansand, Norway

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LOVEMORE GWANZURA Centre for Imported and Tropical Diseases, Department of Infectious Diseases, Ullevaal University Hospital, Oslo, Norway; College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe; Blair Research Institute, Harare, Zimbabwe; Biomedical Research and Training Institute, Harare, Zimbabwe; Department of Epidemiology, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark; Research Unit, Sorlandet Hospital/Department of Health and Sports, Agder University College, Kristiansand, Norway

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PETER R. MASON Centre for Imported and Tropical Diseases, Department of Infectious Diseases, Ullevaal University Hospital, Oslo, Norway; College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe; Blair Research Institute, Harare, Zimbabwe; Biomedical Research and Training Institute, Harare, Zimbabwe; Department of Epidemiology, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark; Research Unit, Sorlandet Hospital/Department of Health and Sports, Agder University College, Kristiansand, Norway

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EDITH NYARADZAI KUREWA Centre for Imported and Tropical Diseases, Department of Infectious Diseases, Ullevaal University Hospital, Oslo, Norway; College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe; Blair Research Institute, Harare, Zimbabwe; Biomedical Research and Training Institute, Harare, Zimbabwe; Department of Epidemiology, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark; Research Unit, Sorlandet Hospital/Department of Health and Sports, Agder University College, Kristiansand, Norway

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NICHOLAS MIDZI Centre for Imported and Tropical Diseases, Department of Infectious Diseases, Ullevaal University Hospital, Oslo, Norway; College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe; Blair Research Institute, Harare, Zimbabwe; Biomedical Research and Training Institute, Harare, Zimbabwe; Department of Epidemiology, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark; Research Unit, Sorlandet Hospital/Department of Health and Sports, Agder University College, Kristiansand, Norway

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HENRIK FRIIS Centre for Imported and Tropical Diseases, Department of Infectious Diseases, Ullevaal University Hospital, Oslo, Norway; College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe; Blair Research Institute, Harare, Zimbabwe; Biomedical Research and Training Institute, Harare, Zimbabwe; Department of Epidemiology, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark; Research Unit, Sorlandet Hospital/Department of Health and Sports, Agder University College, Kristiansand, Norway

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SVEIN GUNNAR GUNDERSEN Centre for Imported and Tropical Diseases, Department of Infectious Diseases, Ullevaal University Hospital, Oslo, Norway; College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe; Blair Research Institute, Harare, Zimbabwe; Biomedical Research and Training Institute, Harare, Zimbabwe; Department of Epidemiology, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark; Research Unit, Sorlandet Hospital/Department of Health and Sports, Agder University College, Kristiansand, Norway

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Up to 75% of women with urinary schistosomiasis have Schistosoma haematobium ova in the genitals. This study aimed to describe the prevalence of gynecologic S. haematobium infection and to differentiate the disease from sexually transmitted infections (STIs). Gynecologic and laboratory investigations for S. haematobium and STIs were performed in 527 women between the ages of 20 and 49 in rural Zimbabwe. Genital homogenous yellow and/or grainy sandy patches, the commonest type of genital pathology, were identified in 243 (46%) women. Grainy sandy patches were significantly associated with S. haematobium ova only. Genital S. haematobium ova was also significantly associated with homogenous yellow sandy patches, mucosal bleeding, and abnormal blood vessels. The presence of ova was not a predictor for ulcers, papillomata, leukoplakia, polyps, or cell atypia. Mucosal sandy patches seem to be pathognomonic for S. haematobium infection in the female genitals. Coexistence of ova and other lesions may not be causal.

Author Notes

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