Author:
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1
Herwaldt BL, Berman JD, 1992. Recommendations for treating leishmaniasis with sodium stibogluconate (Pentostam) and review of pertinent clinical studies. Am J Trop Med Hyg 46 :296–306.
-
2
Soto-Mancipe J, Grogl M, Berman JD, 1993. Evaluation of pentamidine for the treatment of cutaneous leishmaniasis in Colombia. Clin Infect Dis 16 :417–425.
-
3
Velez I, Agudelo S, Hendrickx E, Puerta J, Grogl M, Modabber F, Berman J, 1997. Inefficacy of Allopurinol for Colombian cutaneous leishmaniasis: a randomized, controlled trial. Ann Intern Med 126 :232–236.
-
4
Aronson NE, Wortmann GW, Johnson SC, Jackson JE, Gasser RA Jr, Magill AJ, Endy TP, Coyne PE, Grogl M, Benson PM, Beard JS, Tally JD, Gambel JM, Kreutzer RD, Oster CN, 1998. Safety and efficacy of intravenous sodium stibogluconate in the treatment of leishmaniasis: recent U.S. military experience. Clin Infect Dis 27 :1457–1464.
-
5
Gasser RA Jr, Magil AJ, Oster CN, Franke ED, Grogl M, Berman JD, 1994. Pancreatitis induced by pentavalent antimonial agents during treatment of leishmaniasis. Clin Infect Dis 18 :83–90.
-
6
Low-A-Chee RM, Rose P, Ridley DS, 1983. An outbreak of cutaneous leishmaniasis in Guyana: epidemiology, clinical and laboratory aspects. Ann Trop Med Parasitol 77 :255–260.
-
7
Berman JD, Wyler DJ, 1980. An in vitro model for investigation of chemotherapeutic agents in leishmaniasis. J Infect Dis 142 :83–86.
-
8
Davey RT, Masur H, 1990. Recent advances in the diagnosis, treatment, and prevention of Pneumocystis carinii pneumonia. Antimicrob Agents Chemother 34 :499–504.
-
9
Kreutzer RD, Semko ME, Hendricks LD, Wright N, 1983. Identification of Leishmania spp. by multiple isozyme analysis. Am J Trop Med Hyg 32 :703–715.
-
10
Common Toxicity Criteria of the US National Cancer Institute, CTC Criteria version 2.0: http://ctep.info.nih.gov. The CTC criteria are now called CTCAE version 3.0.
-
11
Lucas CM, Franke ED, Cachay MI, Tejada A, Cruz ME, Kreutzer RD, Barker DC, McCann SH, Watts DM, 1998. Geographic distribution and clinical description of leishmaniasis cases in Peru. Am J Trop Med Hyg 59 :312–317.
-
12
Mendonca MG, de Brito ME, Rodrigues EH, Bandeira V, Jardim ML, Abath FG, 2004. Persistence of leishmania parasites in scars after clinical cure of American cutaneous leishmaniasis: is there a sterile cure? J Infect Dis 189 :1018–1023.
-
13
Lai A, Fat EJSK, Vrede MA, Soetosenojo RM, Lai A, Fat RFM, 2002. Pentamidine, the drug of choice for the treatment of cutaneous leishmaniasis in Surinam. Int J Dermatol 41 :796–800.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 34 | 34 | 11 |
| Full Text Views | 336 | 85 | 0 |
| PDF Downloads | 131 | 22 | 0 |
COMPARISON OF MEGLUMINE ANTIMONIATE AND PENTAMIDINE FOR PERUVIAN CUTANEOUS LEISHMANIASIS
ELLEN M. ANDERSEN
ELLEN M. ANDERSEN
Navy Environmental and Preventive Medicine Unit No. 5, San Diego, California; Hospital Instituto Peruano Seguro Social, Cusco, Peru; Universidad Peruana Cayetano Heredia; Lima, Peru; National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland
Search for other papers by ELLEN M. ANDERSEN in
Current site
Google Scholar
PubMed
Search for other papers by ELLEN M. ANDERSEN in
Current site
Google Scholar
PubMed
MARIA CRUZ-SALDARRIAGA
MARIA CRUZ-SALDARRIAGA
Navy Environmental and Preventive Medicine Unit No. 5, San Diego, California; Hospital Instituto Peruano Seguro Social, Cusco, Peru; Universidad Peruana Cayetano Heredia; Lima, Peru; National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland
Search for other papers by MARIA CRUZ-SALDARRIAGA in
Current site
Google Scholar
PubMed
Search for other papers by MARIA CRUZ-SALDARRIAGA in
Current site
Google Scholar
PubMed
ALEJANDRO LLANOS-CUENTAS
ALEJANDRO LLANOS-CUENTAS
Navy Environmental and Preventive Medicine Unit No. 5, San Diego, California; Hospital Instituto Peruano Seguro Social, Cusco, Peru; Universidad Peruana Cayetano Heredia; Lima, Peru; National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland
Search for other papers by ALEJANDRO LLANOS-CUENTAS in
Current site
Google Scholar
PubMed
Search for other papers by ALEJANDRO LLANOS-CUENTAS in
Current site
Google Scholar
PubMed
MARIA LUZ-CJUNO
MARIA LUZ-CJUNO
Navy Environmental and Preventive Medicine Unit No. 5, San Diego, California; Hospital Instituto Peruano Seguro Social, Cusco, Peru; Universidad Peruana Cayetano Heredia; Lima, Peru; National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland
Search for other papers by MARIA LUZ-CJUNO in
Current site
Google Scholar
PubMed
Search for other papers by MARIA LUZ-CJUNO in
Current site
Google Scholar
PubMed
JUAN ECHEVARRIA
JUAN ECHEVARRIA
Navy Environmental and Preventive Medicine Unit No. 5, San Diego, California; Hospital Instituto Peruano Seguro Social, Cusco, Peru; Universidad Peruana Cayetano Heredia; Lima, Peru; National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland
Search for other papers by JUAN ECHEVARRIA in
Current site
Google Scholar
PubMed
Search for other papers by JUAN ECHEVARRIA in
Current site
Google Scholar
PubMed
CESAR MIRANDA-VERASTEGUI
CESAR MIRANDA-VERASTEGUI
Navy Environmental and Preventive Medicine Unit No. 5, San Diego, California; Hospital Instituto Peruano Seguro Social, Cusco, Peru; Universidad Peruana Cayetano Heredia; Lima, Peru; National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland
Search for other papers by CESAR MIRANDA-VERASTEGUI in
Current site
Google Scholar
PubMed
Search for other papers by CESAR MIRANDA-VERASTEGUI in
Current site
Google Scholar
PubMed
OLGA COLINA
OLGA COLINA
Navy Environmental and Preventive Medicine Unit No. 5, San Diego, California; Hospital Instituto Peruano Seguro Social, Cusco, Peru; Universidad Peruana Cayetano Heredia; Lima, Peru; National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland
Search for other papers by OLGA COLINA in
Current site
Google Scholar
PubMed
Search for other papers by OLGA COLINA in
Current site
Google Scholar
PubMed
JONATHAN D. BERMAN
JONATHAN D. BERMAN
Navy Environmental and Preventive Medicine Unit No. 5, San Diego, California; Hospital Instituto Peruano Seguro Social, Cusco, Peru; Universidad Peruana Cayetano Heredia; Lima, Peru; National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland
Search for other papers by JONATHAN D. BERMAN in
Current site
Google Scholar
PubMed
Search for other papers by JONATHAN D. BERMAN in
Current site
Google Scholar
PubMed
Pentamidine was compared with meglumine antimoniate (Glucantime) for 80 patients with cutaneous leishmaniasis due to Leishmania braziliensis in Peru. Of the 40 patients administered Glucantime (20 mg of antimony [Sb]/kg/day intravenously for 20 days), 31 cured (78%), 6 failed (15%), of which 5 were due to relapse, and 3 were lost to follow-up (7%). Of the 40 patients administered pentamidine (2 mg/kg every other day for seven injections), 14 were cured (35%), 23 failed (58%), and 3 were lost to follow-up (7%). Five pentamidine failures were due to relapse, and 14 failures were due to the presence of parasites two weeks after therapy. Both regimens were well tolerated. Gastrointestinal, musculoskeletal, and total adverse events were not statistically different in either group. Elevations in levels of liver enzymes and pancreatic enzymes were statistically higher in the Glucantime group, but no patient terminated therapy prematurely. In this study, Glucantime was more effective than pentamidine for treatment of L. braziliensis cutaneous leishmaniasis in Peru based on parasitologic as well as clinical criteria.
Author Notes
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1
Herwaldt BL, Berman JD, 1992. Recommendations for treating leishmaniasis with sodium stibogluconate (Pentostam) and review of pertinent clinical studies. Am J Trop Med Hyg 46 :296–306.
-
2
Soto-Mancipe J, Grogl M, Berman JD, 1993. Evaluation of pentamidine for the treatment of cutaneous leishmaniasis in Colombia. Clin Infect Dis 16 :417–425.
-
3
Velez I, Agudelo S, Hendrickx E, Puerta J, Grogl M, Modabber F, Berman J, 1997. Inefficacy of Allopurinol for Colombian cutaneous leishmaniasis: a randomized, controlled trial. Ann Intern Med 126 :232–236.
-
4
Aronson NE, Wortmann GW, Johnson SC, Jackson JE, Gasser RA Jr, Magill AJ, Endy TP, Coyne PE, Grogl M, Benson PM, Beard JS, Tally JD, Gambel JM, Kreutzer RD, Oster CN, 1998. Safety and efficacy of intravenous sodium stibogluconate in the treatment of leishmaniasis: recent U.S. military experience. Clin Infect Dis 27 :1457–1464.
-
5
Gasser RA Jr, Magil AJ, Oster CN, Franke ED, Grogl M, Berman JD, 1994. Pancreatitis induced by pentavalent antimonial agents during treatment of leishmaniasis. Clin Infect Dis 18 :83–90.
-
6
Low-A-Chee RM, Rose P, Ridley DS, 1983. An outbreak of cutaneous leishmaniasis in Guyana: epidemiology, clinical and laboratory aspects. Ann Trop Med Parasitol 77 :255–260.
-
7
Berman JD, Wyler DJ, 1980. An in vitro model for investigation of chemotherapeutic agents in leishmaniasis. J Infect Dis 142 :83–86.
-
8
Davey RT, Masur H, 1990. Recent advances in the diagnosis, treatment, and prevention of Pneumocystis carinii pneumonia. Antimicrob Agents Chemother 34 :499–504.
-
9
Kreutzer RD, Semko ME, Hendricks LD, Wright N, 1983. Identification of Leishmania spp. by multiple isozyme analysis. Am J Trop Med Hyg 32 :703–715.
-
10
Common Toxicity Criteria of the US National Cancer Institute, CTC Criteria version 2.0: http://ctep.info.nih.gov. The CTC criteria are now called CTCAE version 3.0.
-
11
Lucas CM, Franke ED, Cachay MI, Tejada A, Cruz ME, Kreutzer RD, Barker DC, McCann SH, Watts DM, 1998. Geographic distribution and clinical description of leishmaniasis cases in Peru. Am J Trop Med Hyg 59 :312–317.
-
12
Mendonca MG, de Brito ME, Rodrigues EH, Bandeira V, Jardim ML, Abath FG, 2004. Persistence of leishmania parasites in scars after clinical cure of American cutaneous leishmaniasis: is there a sterile cure? J Infect Dis 189 :1018–1023.
-
13
Lai A, Fat EJSK, Vrede MA, Soetosenojo RM, Lai A, Fat RFM, 2002. Pentamidine, the drug of choice for the treatment of cutaneous leishmaniasis in Surinam. Int J Dermatol 41 :796–800.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 34 | 34 | 11 |
| Full Text Views | 336 | 85 | 0 |
| PDF Downloads | 131 | 22 | 0 |