SHORT REPORT: PROSPECTIVE EVALUATION OF A MULTI-TEST STRIP FOR THE DIAGNOSES OF SCRUB AND MURINE TYPHUS, LEPTOSPIROSIS, DENGUE FEVER, AND SALMONELLA TYPHI INFECTION

GEORGE WATT Department of Retrovirology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand; Department of Medicine, Mae Sot Hospital, Mae Sot, Thailand; Department of Medicine, Chiangrai Regional Hospital, Chiangrai, Thailand; Department of Medicine, Prince of Songkla University, Hat Yai, Thailand

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KRISADA JONGSAKUL Department of Retrovirology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand; Department of Medicine, Mae Sot Hospital, Mae Sot, Thailand; Department of Medicine, Chiangrai Regional Hospital, Chiangrai, Thailand; Department of Medicine, Prince of Songkla University, Hat Yai, Thailand

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RONNATRAI RUANGVIRAYUTH Department of Retrovirology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand; Department of Medicine, Mae Sot Hospital, Mae Sot, Thailand; Department of Medicine, Chiangrai Regional Hospital, Chiangrai, Thailand; Department of Medicine, Prince of Songkla University, Hat Yai, Thailand

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PACHAREE KANTIPONG Department of Retrovirology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand; Department of Medicine, Mae Sot Hospital, Mae Sot, Thailand; Department of Medicine, Chiangrai Regional Hospital, Chiangrai, Thailand; Department of Medicine, Prince of Songkla University, Hat Yai, Thailand

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KHACHORNSAKDI SILPAPOJAKUL Department of Retrovirology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand; Department of Medicine, Mae Sot Hospital, Mae Sot, Thailand; Department of Medicine, Chiangrai Regional Hospital, Chiangrai, Thailand; Department of Medicine, Prince of Songkla University, Hat Yai, Thailand

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A multi-test strip dotblot immunoassay for the diagnosis of typhoid fever, scrub typhus, murine typhus, dengue virus infection and leptospirosis was evaluated in Thai adults presenting to hospital with acute, undifferentiated fever. The kit gave multiple positive test results in 33 of 36 patients with defined infections and was therefore not a useful admission diagnostic tool.

Author Notes

Reprint requests: George Watt, Mahidol-Maryland University Tropical Medicine Research Program, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand 10400.
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