3. UPSTREAM RESEARCH TO SUPPORT THE GPELF (BASIC RESEARCH)

3.1 PATHOGENESIS

Christopher L. King
Search for other papers by Christopher L. King in
Current site
Google Scholar
PubMed
Close
and
James W. Kazura
Search for other papers by James W. Kazura in
Current site
Google Scholar
PubMed
Close
Restricted access

Author Notes

  • 1

    Bockarie MJ, Tisch DJ, Kastens W, Alexander ND, Dimber Z, Bockarie F, Ibam E, Alpers MP, Kazura JW, 2002. Mass treatment to eliminate filariasis in Papua New Guinea. N Engl J Med 347 :1841–1848.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 2

    Ravindran B, 2003. Aping Jane Goodall: insights into human lymphatic filariasis. Trends Parasitol 19 :105–109.

  • 3

    Amaral F, Dreyer G, Figueredo-Silva J, Noroes J, Cavalcanti A, Samico SC, Santos A, Coutinho A, 1994. Live adult worms detected by ultrasonography in human Bancroftian filariasis. Am J Trop Med Hyg 50 :753–757.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 4

    Freedman DO, de Almeida Filho PJ, Besh S, Maia e Silva MC, Braga C, Maciel A, 1994. Lymphoscintigraphic analysis of lymphatic abnormalities in symptomatic and asymptomatic human filariasis. J Infect Dis 170 :927–933.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 5

    Witte CL, Witte MH, 1999. Diagnostic and interventional imaging of lymphatic disorders. Int Angiol 18 :25–30.

  • 6

    Dreyer G, Noroes J, Figueredo-Silva J, Piessens WF, 2000. Pathogenesis of lymphatic disease in Bancroftian filariasis: a clinical perspective. Parasitol Today 16 :544–548.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 7

    Tobian AA, Tarongka N, Baisor M, Bockarie M, Kazura JW, King CL, 2003. Sensitivity and specificity of ultrasound detection and risk factors for filarial-associated hydrocoeles. Am J Trop Med Hyg 68 :638–642.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 8

    Figueredo-Silva J, Noroes J, Cedenho A, Dreyer G, 2002. The histopathology of bancroftian filariasis revisited: the role of the adult worm in the lymphatic-vessel disease. Ann Trop Med Parasitol 96 :531–541.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 9

    Karkkainen MJ, Makinen T, Alitalo K, 2002. Lymphatic endothelium: a new frontier of metastasis research. Nat Cell Biol 4 :E2–E5.

  • 10

    Hanash S, 2003. Disease proteomics. Nature 422 :226–232.

  • 11

    Esterre P, Plichart C, Huin-Blondey MO, Nguyen L, 2000. Role of streptococcal infection in the acute pathology of lymphatic filariasis. Parasite 7 :91–94.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 12

    Onapa AW, Simonsen PE, Pedersen EM, 2001. Non-filarial elephantiasis in the Mt. Elgon area (Kapchorwa District) of Uganda. Acta Trop 78 :171–176.

  • 13

    Nacher M, Singhasivanon P, Traore B, Vannaphan S, Gay F, Chindanond D, Franetich JF, Mazier D, Looareesuwan S, 2002. Helminth infections are associated with protection from cerebral malaria and increased nitrogen derivatives concentrations in Thailand. Am J Trop Med Hyg 66 :304–309.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 14

    Nacher M, 2004. Interactions between worm infections and malaria. Clin Rev Allergy Immunol 26 :85–92.

  • 15

    Le Hesran JY, Akiana J, Ndiaye el HM, Dia M, Senghor P, Konnate L, 2004. Severe malaria attack is associated with high prevalence of Ascaris lumbricoides infection among children in rural Senegal. Trans R Soc Trop Med Hyg 98 :397–399.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 16

    Spiegel A, Tall A, Raphenon G, Trape JF, Druilhe P, 2003. Increased frequency of malaria attacks in subjects co-infected by intestinal worms and Plasmodium falciparum malaria. Trans R Soc Trop Med Hyg 97 :198–199.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 17

    Saint Andre A, Blackwell NM, Hall LR, Hoerauf A, Brattig NW, Volkmann L, Taylor MJ, Ford L, Hise AG, Lass JH, Diaconu E, Pearlman E, 2002.The role of endosymbiotic Wolbachia bacteria in the pathogenesis of river blindness. Science 295 :1892–1895.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 18

    Taylor MJ, 2002. A new insight into the pathogenesis of filarial disease. Curr Mol Med 2 :299–302.

  • 19

    King CL, Kumaraswami V, Poindexter RW, Kumari S, Jayaraman K, Alling DW, Ottesen EA, Nutman TB, 1992. Immunologic tolerance in lymphatic filariasis. Diminished parasite-specific T and B lymphocyte precursor frequency in the microfilaremic state. J Clin Invest 89 :1403–1410.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 20

    Nutman TB, Kumaraswami V, 2001. Regulation of the immune response in lymphatic filariasis: perspectives on acute and chronic infection with Wuchereria bancrofti in South India. Parasite Immunol 23 :389–399.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 21

    Beaver PC, 1970. Filariasis without microfilaremia. Am J Trop Med Hyg 19 :181–189.

  • 22

    King CL, Connelly M, Alpers MP, Bockarie M, Kazura JW, 2001. Transmission intensity determines lymphocyte responsiveness and cytokine bias in human lymphatic filariasis. J Immunol 166 :7427–7436.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 23

    Maizels RM, Gomez-Escobar N, Gregory WF, Murray J, Zang X, 2001. Immune evasion genes from filarial nematodes. Int J Parasitol 31 :889–898.

  • 24

    Semnani RT, Sabzevari H, Iyer R, Nutman TB, 2001. Filarial antigens impair the function of human dendritic cells during differentiation. Infect Immun 69 :5813–5822.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 25

    Semnani RT, Law M, Kubofcik J, Nutman TB, 2004. Filaria-induced immune evasion: suppression by the infective stage of Brugia malayi at the earliest host-parasite interface. J Immunol 172 :6229–6238.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 26

    Ramalho-Pinto FJ, Carvalho EM, Horta MF, 1992. Mechanisms of evasion of Schistosoma mansoni schistosomula to the lethal activity of complement. Mem Inst Oswaldo Cruz 87 (Suppl 4):111–116.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 27

    Ottesen EA, Neva FA, Paranjape RS, Tripathy SP, Thiruvengadam KV, Beaven MA, 1979. Specific allergic sensitsation to filarial antigens in tropical eosinophilia syndrome. Lancet 1 :1158–1161.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 28

    Lobos E, Zahn R, Weiss N, Nutman TB, 1996. A major allergen of lymphatic filarial nematodes is a parasite homolog of the gamma-glutamyl transpeptidase. Mol Med 2 :712–724.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 29

    Choi EH, Nutman TB, Chanock SJ, 2003. Genetic variation in immune function and susceptibility to human filariasis. Expert Rev Mol Diagn 3 :367–374.

  • 30

    Finegold DN, Kimak MA, Lawrence EC, Levinson KL, Cherniske EM, Pober BR, Dunlap JW, Ferrell RE, 2001. Truncating mutations in FOXC2 cause multiple lymphedema syndromes. Hum Mol Genet 10 :1185–1189.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 31

    Brabin L, 1990. Sex differentials in susceptibility to lymphatic filariasis and implications for maternal child immunity. Epidemiol Infect 105 :335–353.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 32

    Ash LR, 1971. Preferential susceptibility of male jirds (Meriones unguiculatus) to infection with Brugia pahangi.J Parasitol 57 :777–780.

Past two years Past Year Past 30 Days
Abstract Views 578 503 26
Full Text Views 220 5 0
PDF Downloads 64 7 2
 

 

 

 
 
Affiliate Membership Banner
 
 
Research for Health Information Banner
 
 
CLOCKSS
 
 
 
Society Publishers Coalition Banner
Save