• 1

    White AC Jr, Fischer PR, 2003. Schistosomiasis. Feigen RD, Cherry JD, Demmler GJ, Kaplan SL, eds. Textbook of Pediatric Infectious Diseases. Fifth Edition. Philadelphia: W.B. Saunders, 2825–2834.

  • 2

    Doumenge J, Mott K, Cheung C, Villenave D, Chapuis O, Perrin M, Reaud-Thomas G, 1987. Atlas of the Global Distribution of Schistosomiasis. Bordeaux: Presses Universitaires de Bordeaux, World Health Organization.

  • 3

    Karanja DM, Colley DG, Nahlen BL, Ouma JH, Secor WE, 1997. Studies on schistosomiasis in western Kenya: I. Evidence for immune-facilitated excretion of schistosome eggs from patients with Schistosoma mansoni and human immunodeficiency virus coinfections. Am J Trop Med Hyg 56 :515–521.

    • Search Google Scholar
    • Export Citation
  • 4

    Pyrrho Ados S, Ramos JA, Neto RM, Silva CS, Lenzi HL, Takiya CM, Gattass CR, 2002. Dexamethasone, a drug for attenuation of Schistosoma mansoni infection morbidity. Antimicrob Agents Chemother 46 :3490–3498.

    • Search Google Scholar
    • Export Citation
  • 5

    Watanabe K, Shinbo T, Kojima M, Naito M, Tanahashi N, Nara M, 1989. B-cell lymphoma associated with eosinophilia. Cancer 64 :1682–1685.

  • 6

    Murata K, Yamada Y, Kamihira S, Atogami S, Tsukasaki K, Momita S, Amagasaki T, Sadamori N, Tomonaga M, Kinoshita K, Ichimaru M, 1992. Frequency of eosinophilia in adult T-cell leukemia/lymphoma. Cancer 69 :966–971.

    • Search Google Scholar
    • Export Citation
  • 7

    Menon BS, Abdullah MS, Mahamud F, Singh B, 1999. Intestinal parasites in Malaysian children with cancer. J Trop Pediatr 45 :241–242.

  • 8

    Guarner J, Matilde-Nava T, Villasenor-Flores R, Sanchez-Mejorada G, 1997. Frequency of intestinal parasites in adult cancer patients in Mexico. Arch Med Res 28 :219–222.

    • Search Google Scholar
    • Export Citation
  • 9

    Hancock K, Tsang VC, 1986. Development and optimization of the FAST-ELISA for detecting antibodies to Schistosoma mansoni. J Immunol Methods 92 :167–176.

    • Search Google Scholar
    • Export Citation

 

 

 

 

SYMPTOMS OF INTESTINAL SCHISTOSOMIASIS PRESENTING DURING TREATMENT OF LARGE B CELL LYMPHOMA

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  • 1 Department of Internal Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, Texas; Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M.D. Anderson Cancer Center, Houston, Texas

We report a case of chronic intestinal schistosomiasis presenting in a previously asymptomatic 34-year-old woman from Saudi Arabia with large B cell lymphoma. The patient presented with abdominal pain, constipation, recurrent rectal bleeding, and persistent mild eosinophilia during chemotherapy. Stools were repeatedly negative for parasite ova, but duodenal and colonic biopsies demonstrated Schistosoma eggs and eosinophilic granulomatous inflammation. Immunosuppressed patients with schistosomiasis may have diminished egg excretion. Diagnosis requires a high index of suspicion since stool test results may be negative and intestinal biopsies may be needed to make the diagnosis.

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