ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1
Ottesen EA, Duke BOL, Karam M, Behbehani K, 1997. Strategies and tools for the control/elimination of lymphatic filariasis. Bull World Health Organ 75 :491–503.
-
2
Addiss DG, Beach MJ, Streit TG, Lutwick S, LeConte FH, Lafontant JG, Lammie PJ, 1997. Efficacy and tolerance of combined single-dose ivermectin and albendazole for Wuchereria bancrofti microfilaremia in Haitian children. Lancet 350 :480–484.
-
3
Ottesen EA, Ismail MM, Horton J, 1999. The role of albendazole in programs to eliminate lymphatic filariasis. Parasitol Today 15 :382–386.
-
4
Stephenson LS, Latham MC, Ottesen EA, 2000. Malnutrition and parasitic helminth infections. Parasitology 121 (Suppl):S23–S38.
-
5
Drake LJ, Bundy DAP, 2001. Multiple helminth infections in children: impact and control. Parasitology 122 :S73–S81.
-
6
Stephenson LS, Latham MC, Kurz KM, Kinoti SM, Brigham H, 1989. Treatment with a single dose of albendazole improves growth of Kenyan schoolchildren with hookworm, Trichuris trichiura and Ascaris lumbricoides infections. Am J Trop Med Hyg 41 :78–87.
-
7
Stephenson LS, Holland CV, Cooper ES, 2000. The public health importance of Trichuris trichiura.Parasitology 121 (Suppl):S73–S95.
-
8
Crompton DWT, 2000. The public health importance of hookworm disease. Parasitology 121 (Suppl):S39–S50.
-
9
O’Lorcain P, Holland CV, 2000. The public health importance of Ascaris lumbricoides. Parasitology 121 (Suppl):S51–S71.
-
10
Beach MJ, Streit TG, Addiss DG, Prospere R, Roberts JM, Lammie PJ, 1999. Assessment of combined ivermectin and albendazole for treatment of intestinal helminth and Wuchereria bancrofti infections in Haitian school children. Am J Trop Med Hyg 60 :479–486.
-
11
Mani TR, Rajendran R, Munirathinam A, Sunish IP, Abdullah SMd, Augustin DJ, Satyanarayana K, 2002. Efficacy of co-administration of albendazole and diethylcarbamazine against geohelminthiases: a study from south India. Trop Med Int Health 7 :541–548.
-
12
Belizario VY, Amarillo ME, de Leon WU, de los Reyes AE, Bugayong MG, Macatangay BJC, 2003. A comparison of the efficacy of single doses of albendazole, ivermectin, and diethylcarbamazine alone or in combinations against Ascaris and Trichuris spp. Bull World Health Organ 81 :35–42.
-
13
McLaughlin SI, Radday J, Carmel M, Addiss DG, Lammie PJ, Lammie J, Rheingans R, Lafontant J, 2003. Frequency, severity, and costs of adverse reactions following mass treatment for lymphatic filariasis using diethylcarbamazine and albendazole, Leogane, Haiti 2000. Am J Trop Med Hyg 68 :568–573.
-
14
Bockarie MJ, Tisch DJ, Kastens W, Alexander ND, Dimber Z, Bockarie F, Ibam E, Alpers MP, Kazura JW, 2002. Mass treatment to eliminate filariasis in Papua New Guinea. N Engl J Med. 347 :1841–1848.
-
15
Mathieu E, Deming M, Lammie P, McLaughlin S, Beach M, Deodat DJ, Addiss D, 2003. Comparison of methods for estimating drug coverage for filariasis elimination, Leogane, Haiti. Trans R Soc Trop Med Hyg 97 :501–505.
-
16
World Health Organization, 1996. Report of the WHO Informal Consultation on Hookworm Infection and Anemia in Girls and Women. Geneva: World Health Organization. WHO/CTD/SIP/96.1
-
17
Torlesse H, Hodges M, 2001. Albendazole therapy and reduced decline in haemoglobin concentration during pregnancy (Sierra Leone). Trans R Soc Trop Med Hyg 95 :195–201.
-
18
Asaolu SO, Holland CV, Crompton DWT, 1991. Community control of Ascaris lumbricoides in rural Oyo State, Nigeria: mass, targeted and selective treatment with levamisole. Parasitology 103 :291–298.
-
19
Olsen A, 1998. The proportion of helminth infections in a community in western Kenya which would be treated by mass chemotherapy of schoolchildren. Trans R Soc Trop Med Hyg 92 :144–148.
-
20
Jancloes MF, Cornet P, Thienpoint D, 1979. Mass control of ascariasis with single oral doses of levamisole. A controlled comparison in 3,056 subjects between three incomplete population coverages. Trop Geogr Med 31 :111–122.
-
21
Thein-Hlaing, Than-Saw, Myat-Lay-Kyin, 1991. The impact of three-monthly age-targetted chemotherapy on Ascaris lumbricoides infection. Trans R Soc Trop Med Hyg 85 :519–522.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 525 | 471 | 25 |
| Full Text Views | 229 | 4 | 0 |
| PDF Downloads | 58 | 5 | 0 |
COMMUNITY-WIDE REDUCTION IN PREVALENCE AND INTENSITY OF INTESTINAL HELMINTHS AS A COLLATERAL BENEFIT OF LYMPHATIC FILARIASIS ELIMINATION PROGRAMS
MADSEN BEAU DE ROCHARS
MADSEN BEAU DE ROCHARS
Hopital Ste. Croix, Leogane, Haiti; Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Center for Tropical Disease Research and Training, University of Notre Dame, Notre Dame, Indiana
Search for other papers by MADSEN BEAU DE ROCHARS in
Current site
Google Scholar
PubMed
Search for other papers by MADSEN BEAU DE ROCHARS in
Current site
Google Scholar
PubMed
ABDEL N. DIRENY
ABDEL N. DIRENY
Hopital Ste. Croix, Leogane, Haiti; Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Center for Tropical Disease Research and Training, University of Notre Dame, Notre Dame, Indiana
Search for other papers by ABDEL N. DIRENY in
Current site
Google Scholar
PubMed
Search for other papers by ABDEL N. DIRENY in
Current site
Google Scholar
PubMed
JACQUELIN M. ROBERTS
JACQUELIN M. ROBERTS
Hopital Ste. Croix, Leogane, Haiti; Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Center for Tropical Disease Research and Training, University of Notre Dame, Notre Dame, Indiana
Search for other papers by JACQUELIN M. ROBERTS in
Current site
Google Scholar
PubMed
Search for other papers by JACQUELIN M. ROBERTS in
Current site
Google Scholar
PubMed
DAVID G. ADDISS
DAVID G. ADDISS
Hopital Ste. Croix, Leogane, Haiti; Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Center for Tropical Disease Research and Training, University of Notre Dame, Notre Dame, Indiana
Search for other papers by DAVID G. ADDISS in
Current site
Google Scholar
PubMed
Search for other papers by DAVID G. ADDISS in
Current site
Google Scholar
PubMed
JEANNE RADDAY
JEANNE RADDAY
Hopital Ste. Croix, Leogane, Haiti; Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Center for Tropical Disease Research and Training, University of Notre Dame, Notre Dame, Indiana
Search for other papers by JEANNE RADDAY in
Current site
Google Scholar
PubMed
Search for other papers by JEANNE RADDAY in
Current site
Google Scholar
PubMed
MICHAEL J. BEACH
MICHAEL J. BEACH
Hopital Ste. Croix, Leogane, Haiti; Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Center for Tropical Disease Research and Training, University of Notre Dame, Notre Dame, Indiana
Search for other papers by MICHAEL J. BEACH in
Current site
Google Scholar
PubMed
Search for other papers by MICHAEL J. BEACH in
Current site
Google Scholar
PubMed
THOMAS G. STREIT
THOMAS G. STREIT
Hopital Ste. Croix, Leogane, Haiti; Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Center for Tropical Disease Research and Training, University of Notre Dame, Notre Dame, Indiana
Search for other papers by THOMAS G. STREIT in
Current site
Google Scholar
PubMed
Search for other papers by THOMAS G. STREIT in
Current site
Google Scholar
PubMed
DESIRE DARDITH
DESIRE DARDITH
Hopital Ste. Croix, Leogane, Haiti; Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Center for Tropical Disease Research and Training, University of Notre Dame, Notre Dame, Indiana
Search for other papers by DESIRE DARDITH in
Current site
Google Scholar
PubMed
Search for other papers by DESIRE DARDITH in
Current site
Google Scholar
PubMed
JACK GUY LAFONTANT
JACK GUY LAFONTANT
Hopital Ste. Croix, Leogane, Haiti; Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Center for Tropical Disease Research and Training, University of Notre Dame, Notre Dame, Indiana
Search for other papers by JACK GUY LAFONTANT in
Current site
Google Scholar
PubMed
Search for other papers by JACK GUY LAFONTANT in
Current site
Google Scholar
PubMed
PATRICK J. LAMMIE
PATRICK J. LAMMIE
Hopital Ste. Croix, Leogane, Haiti; Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Center for Tropical Disease Research and Training, University of Notre Dame, Notre Dame, Indiana
Search for other papers by PATRICK J. LAMMIE in
Current site
Google Scholar
PubMed
Search for other papers by PATRICK J. LAMMIE in
Current site
Google Scholar
PubMed
Annual mass treatment with antifilarial drugs is the cornerstone of the global program to eliminate lymphatic filariasis (LF). Although the primary goal of the program is to interrupt transmission of LF, additional public health benefits also are expected because of the known anthelminthic properties of these drugs. Since rapid re-infection with intestinal helminths occurs following treatment, annual de-worming may not be sufficient to produce a lasting reduction in the prevalence and intensity of these infections. We conducted stool examinations in four sentinel communities before and approximately nine months after each of two rounds of mass drug administration (MDA) with diethylcarbamazine and albendazole in the context of an LF elimination program in Leogane, Haiti. At baseline, overall Ascaris, Trichuris, and hookworm infection prevalences were 20.9%, 34.0%, and 11.2%, respectively (n = 2,716 stools). Nine months after the second MDA, Ascaris, Trichuris and hookworm prevalences had decreased significantly, to 14.1%, 14.6%, and 2.0%, respectively (n = 814 stools). Infection intensity decreased significantly for all three parasites as well. These results demonstrate that substantial reductions in intestinal helminth infections are associated with mass treatment of filariasis in Haiti and are consistent with the conclusion that high levels of coverage for the LF program can decrease transmission of geohelminths.
Author Notes
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1
Ottesen EA, Duke BOL, Karam M, Behbehani K, 1997. Strategies and tools for the control/elimination of lymphatic filariasis. Bull World Health Organ 75 :491–503.
-
2
Addiss DG, Beach MJ, Streit TG, Lutwick S, LeConte FH, Lafontant JG, Lammie PJ, 1997. Efficacy and tolerance of combined single-dose ivermectin and albendazole for Wuchereria bancrofti microfilaremia in Haitian children. Lancet 350 :480–484.
-
3
Ottesen EA, Ismail MM, Horton J, 1999. The role of albendazole in programs to eliminate lymphatic filariasis. Parasitol Today 15 :382–386.
-
4
Stephenson LS, Latham MC, Ottesen EA, 2000. Malnutrition and parasitic helminth infections. Parasitology 121 (Suppl):S23–S38.
-
5
Drake LJ, Bundy DAP, 2001. Multiple helminth infections in children: impact and control. Parasitology 122 :S73–S81.
-
6
Stephenson LS, Latham MC, Kurz KM, Kinoti SM, Brigham H, 1989. Treatment with a single dose of albendazole improves growth of Kenyan schoolchildren with hookworm, Trichuris trichiura and Ascaris lumbricoides infections. Am J Trop Med Hyg 41 :78–87.
-
7
Stephenson LS, Holland CV, Cooper ES, 2000. The public health importance of Trichuris trichiura.Parasitology 121 (Suppl):S73–S95.
-
8
Crompton DWT, 2000. The public health importance of hookworm disease. Parasitology 121 (Suppl):S39–S50.
-
9
O’Lorcain P, Holland CV, 2000. The public health importance of Ascaris lumbricoides. Parasitology 121 (Suppl):S51–S71.
-
10
Beach MJ, Streit TG, Addiss DG, Prospere R, Roberts JM, Lammie PJ, 1999. Assessment of combined ivermectin and albendazole for treatment of intestinal helminth and Wuchereria bancrofti infections in Haitian school children. Am J Trop Med Hyg 60 :479–486.
-
11
Mani TR, Rajendran R, Munirathinam A, Sunish IP, Abdullah SMd, Augustin DJ, Satyanarayana K, 2002. Efficacy of co-administration of albendazole and diethylcarbamazine against geohelminthiases: a study from south India. Trop Med Int Health 7 :541–548.
-
12
Belizario VY, Amarillo ME, de Leon WU, de los Reyes AE, Bugayong MG, Macatangay BJC, 2003. A comparison of the efficacy of single doses of albendazole, ivermectin, and diethylcarbamazine alone or in combinations against Ascaris and Trichuris spp. Bull World Health Organ 81 :35–42.
-
13
McLaughlin SI, Radday J, Carmel M, Addiss DG, Lammie PJ, Lammie J, Rheingans R, Lafontant J, 2003. Frequency, severity, and costs of adverse reactions following mass treatment for lymphatic filariasis using diethylcarbamazine and albendazole, Leogane, Haiti 2000. Am J Trop Med Hyg 68 :568–573.
-
14
Bockarie MJ, Tisch DJ, Kastens W, Alexander ND, Dimber Z, Bockarie F, Ibam E, Alpers MP, Kazura JW, 2002. Mass treatment to eliminate filariasis in Papua New Guinea. N Engl J Med. 347 :1841–1848.
-
15
Mathieu E, Deming M, Lammie P, McLaughlin S, Beach M, Deodat DJ, Addiss D, 2003. Comparison of methods for estimating drug coverage for filariasis elimination, Leogane, Haiti. Trans R Soc Trop Med Hyg 97 :501–505.
-
16
World Health Organization, 1996. Report of the WHO Informal Consultation on Hookworm Infection and Anemia in Girls and Women. Geneva: World Health Organization. WHO/CTD/SIP/96.1
-
17
Torlesse H, Hodges M, 2001. Albendazole therapy and reduced decline in haemoglobin concentration during pregnancy (Sierra Leone). Trans R Soc Trop Med Hyg 95 :195–201.
-
18
Asaolu SO, Holland CV, Crompton DWT, 1991. Community control of Ascaris lumbricoides in rural Oyo State, Nigeria: mass, targeted and selective treatment with levamisole. Parasitology 103 :291–298.
-
19
Olsen A, 1998. The proportion of helminth infections in a community in western Kenya which would be treated by mass chemotherapy of schoolchildren. Trans R Soc Trop Med Hyg 92 :144–148.
-
20
Jancloes MF, Cornet P, Thienpoint D, 1979. Mass control of ascariasis with single oral doses of levamisole. A controlled comparison in 3,056 subjects between three incomplete population coverages. Trop Geogr Med 31 :111–122.
-
21
Thein-Hlaing, Than-Saw, Myat-Lay-Kyin, 1991. The impact of three-monthly age-targetted chemotherapy on Ascaris lumbricoides infection. Trans R Soc Trop Med Hyg 85 :519–522.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 525 | 471 | 25 |
| Full Text Views | 229 | 4 | 0 |
| PDF Downloads | 58 | 5 | 0 |