SHORT REPORT: A MAJOR GENOTYPE OF JAPANESE ENCEPHALITIS VIRUS CURRENTLY CIRCULATING IN JAPAN

SHAO-PING MA Division of Epidemiology, Department of Infectious Diseases, Oita Medical University, Oita, Japan; Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health, Tokyo, Japan; Department of Virology, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan; Oita Prefectural Institute of Health and Environment, Oita, Japan

Search for other papers by SHAO-PING MA in
Current site
Google Scholar
PubMed
Close
,
YASUKO YOSHIDA Division of Epidemiology, Department of Infectious Diseases, Oita Medical University, Oita, Japan; Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health, Tokyo, Japan; Department of Virology, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan; Oita Prefectural Institute of Health and Environment, Oita, Japan

Search for other papers by YASUKO YOSHIDA in
Current site
Google Scholar
PubMed
Close
,
YOSHIHIRO MAKINO Division of Epidemiology, Department of Infectious Diseases, Oita Medical University, Oita, Japan; Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health, Tokyo, Japan; Department of Virology, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan; Oita Prefectural Institute of Health and Environment, Oita, Japan

Search for other papers by YOSHIHIRO MAKINO in
Current site
Google Scholar
PubMed
Close
,
MASAYUKI TADANO Division of Epidemiology, Department of Infectious Diseases, Oita Medical University, Oita, Japan; Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health, Tokyo, Japan; Department of Virology, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan; Oita Prefectural Institute of Health and Environment, Oita, Japan

Search for other papers by MASAYUKI TADANO in
Current site
Google Scholar
PubMed
Close
,
TETSURO ONO Division of Epidemiology, Department of Infectious Diseases, Oita Medical University, Oita, Japan; Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health, Tokyo, Japan; Department of Virology, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan; Oita Prefectural Institute of Health and Environment, Oita, Japan

Search for other papers by TETSURO ONO in
Current site
Google Scholar
PubMed
Close
, and
MASAO OGAWA Division of Epidemiology, Department of Infectious Diseases, Oita Medical University, Oita, Japan; Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health, Tokyo, Japan; Department of Virology, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan; Oita Prefectural Institute of Health and Environment, Oita, Japan

Search for other papers by MASAO OGAWA in
Current site
Google Scholar
PubMed
Close
Restricted access

A 240-nucleotide sequence of the capsid/premembrane gene region of 23 Japanese encephalitis virus (JEV) strains isolated in Tokyo and Oita, Japan was determined and phylogenetic analyses were performed. All the strains clustered into two distinct genotypes (III and I). All strains isolated before 1991 belonged to genotype III, while those isolated after 1994 belonged to genotype I. In addition, the strains of the genotype I isolated in Japan showed a close genetic relationship with those from Korea and Malaysia.

Author Notes

Reprint requests: Shao-Ping Ma, Division of Epidemiology, Department of Infectious Diseases, Oita Medical University, Hasamamachi, Oita 879-5593, Japan, Telephone: 81-97-586-5735, Fax: 81-97-586-5739, E-mail: masp@oita-med.ac.jp.
  • 1

    Lindenbach BD, Rice CM, 2001. Flaviviridae: The virus and their replication. Knipe DM, Howley PM, Griffin DE, Martin MA, Lamb RA, Roizman B, Straus SE, eds. Virology. Philadelphia: Lippincott Williams and Wilkins, 991–1125.

  • 2

    Hori H, Morita K, Igarashi A, 1986. Oligonucleotide fingerprint analysis on Japanese encephalitis virus strains isolated in Japan and Thailand. Acta Virol 30 :353–359.

    • Search Google Scholar
    • Export Citation
  • 3

    Banerjee K, Ranadive SN, 1989. Oligonucleotiede fingerprint analysis of Japanese encephalitis virus strains of different geographical origin. Indian J Med Res 89 :201–216.

    • Search Google Scholar
    • Export Citation
  • 4

    Chen WR, Tesh RB, Rico-Hesse R, 1990. Genetic variation of Japanese encephalitis virus in nature. J Gen Virol 71 :2915–2922.

  • 5

    Chen WR, Rico-Hesse R, Tesh RB, 1992. A new genotype of Japanese encephalitis virus from Indonesia. Am J Trop Med Hyg 47 :61–69.

  • 6

    Huong VTQ, Ha DQ, Deubel V, 1993. Genetic study of Japanese encephalitis viruses from Vietnam. Am J Trop Med Hyg 49 :538–544.

  • 7

    Chung YJ, Nam JH, Ban SJ, Cho HW, 1996. Antigenic and genetic analysis of Japanese encephalitis virus isolated from Korea. Am J Trop Med Hyg 55 :91–97.

    • Search Google Scholar
    • Export Citation
  • 8

    Ma SP, Arakaki S, Makino Y, Fukunaga T, 1996. Molecular epidemiology of Japanese encephalitis virus in Okinawa. Microbiol Immunol 40 :847–855.

    • Search Google Scholar
    • Export Citation
  • 9

    Tsuchie H, Oda K, Vythilingam I, Thayan R, Vijayamalar B, Sinniah M, Wada T, Tanaka H, Kurimura T, Igarashi A, 1997. Genotypes of Japanese encephalitis virus isolates in three states in Malaysia. Am J Trop Med Hyg 56 :153–158.

    • Search Google Scholar
    • Export Citation
  • 10

    Jan LR, Yueh YY, Wu YC, Horng CB, Wang GR, 2000. Genetic variation of Japanese encephalitis virus in Taiwan. Am J Trop Med Hyg 62 :446–452.

    • Search Google Scholar
    • Export Citation
  • 11

    Takegami T, Ishak H, Miyamoto C, Hirai Y, Kamimura K, 2000. Isolation and molecular comparison of Japanese encephalitis virus in Ishikawa, Japan. Jpn J Infect Dis 53 :178–179.

    • Search Google Scholar
    • Export Citation
  • 12

    Nam JH, Chae SL, Won SY, Kim EJ, Yoon KS, Kim BI, Jeong YS, Cho HW, 2001. Genetic heterogeneity of Japanese encephalitis virus assessed via analysis of the full-length genome sequence of a Korean isolate. Am J Trop Med Hyg 65 :388–392.

    • Search Google Scholar
    • Export Citation
  • 13

    Pyke AT, Williams DT, Nisbet DJ, Den Hurk AF, Taylor CT, Johansen CA, Macdonald J, Hall RA, Simmons RJ, Mason RJV, Lee JM, Ritchie SA, Smith GA, Mackenzie JS, 2001. The appearance of a second genotype of Japanese encephalitis virus in the Australasian region. Am J Trop Med Hyg 65 :747–753.

    • Search Google Scholar
    • Export Citation
  • 14

    Ali A, Igarashi A, 1997. Antigenic and genetic variations among Japanese encephalitis virus strains belonging to genotype 1. Microbiol Immunol 41 :241–252.

    • Search Google Scholar
    • Export Citation
  • 15

    Saitou N, Nei M, 1987. The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 4 :406–425.

  • 16

    Thompson JD, Higgins DG, Gibson TJ, 1994. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice. Nucleic Acids Res 22 :4673–4680.

    • Search Google Scholar
    • Export Citation
  • 17

    Page RDM, 1996. Treeview: an application to display phylogenetic trees on personal computers. Comp Appl Biosci 12 :357–358.

  • 18

    Igarashi A, 2002. Control of Japanese encephalitis in Japan: immunization of humans and animals, and vector control. Curr Top Microbiol Immunol 267 :139–152.

    • Search Google Scholar
    • Export Citation
  • 19

    Matsunaga Y, Yabe S, Taniguchi K, Nakayama M, Kurane I, 1999. Current status of Japanese encephalitis in Japan. Kansenshogaku Zasshi 73 :97–103.

    • Search Google Scholar
    • Export Citation
Past two years Past Year Past 30 Days
Abstract Views 21 21 7
Full Text Views 433 257 0
PDF Downloads 74 20 0
 
Membership Banner
 
 
 
Affiliate Membership Banner
 
 
Research for Health Information Banner
 
 
CLOCKSS
 
 
 
Society Publishers Coalition Banner
Save