CASE REPORT: GNATHOSTOMIASIS IN TWO TRAVELERS TO ZAMBIA

DEVON C. HALE Department of Medicine, Division of Infectious Diseases University of Utah, Salt Lake City, Utah; Department of Clinical Microbiology and Infectious Diseases, University of the Witwatersrand and the National Health Laboratory Service, Johannesburg, South Africa

Search for other papers by DEVON C. HALE in
Current site
Google Scholar
PubMed
Close
,
LUCILLE BLUMBERG Department of Medicine, Division of Infectious Diseases University of Utah, Salt Lake City, Utah; Department of Clinical Microbiology and Infectious Diseases, University of the Witwatersrand and the National Health Laboratory Service, Johannesburg, South Africa

Search for other papers by LUCILLE BLUMBERG in
Current site
Google Scholar
PubMed
Close
, and
JOHN FREAN Department of Medicine, Division of Infectious Diseases University of Utah, Salt Lake City, Utah; Department of Clinical Microbiology and Infectious Diseases, University of the Witwatersrand and the National Health Laboratory Service, Johannesburg, South Africa

Search for other papers by JOHN FREAN in
Current site
Google Scholar
PubMed
Close
Restricted access

Gnathostomiasis is a systemic infection caused by migrating nematode larvae of the genus Gnathostoma. It is a zoonosis involving a wide variety of animals as intermediate and definitive hosts, and consumption of raw fish is the main risk factor. The condition is most commonly seen in southeastern Asia, but has been described in a number of other countries, all outside Africa. We report the infection in two travelers returning from southcentral Africa, who presented with non-specific symptoms and marked eosinophilia, and in whom schistosomiasis was initially suspected. The typical migratory skin lesions of gnathostomiasis appeared later. The infections responded well to albendazole. The patients acquired the infection in western Zambia; this region of Africa appears to be a newly identified risk area for gnathostomiasis in tourists who indulge in eating raw freshwater fish.

Author Notes

Reprint requests: DeVon C. Hale, Department of Medicine, Division of Infectious Diseases, University of Utah, 30 North 1900 East, Room 4B319, Salt Lake City, UT 84132-2405.
  • 1

    Rusnak JM, Lucey DR, 1993. Clinical gnathostomiasis: case report and review of the English-language literature. Clin Infect Dis 16 :33–50.

    • Search Google Scholar
    • Export Citation
  • 2

    Camacho SPD, Ramos MZ, Torrecillas EP, Ramirez IO, Velazquez RC, Gaxiola AF, Heredia JB, Willms K, Akahane H, Ogata K, Nawa Y, 1998. Clinical manifestations and immuno-diagnosis of gnathostomiasis in Culiacan, Mexico. Am J Trop Med Hyg 59 :908–915.

    • Search Google Scholar
    • Export Citation
  • 3

    Akahane H, Shibue K, Shimizu A, Toshitani S, 1998. Human gnathostomiasis caused by Gnathostoma doloresi, with particular reference to the parasitological investigation of the causative agent. Ann Trop Med Parasitol 92 :721–726.

    • Search Google Scholar
    • Export Citation
  • 4

    Chhuon H, Sangkin K, Voenthal Y, 1976. Oedèmes mobiles de la face et du cou souvis de localisation intraoculaire de Gnatostoma spinigerum.Bull Soc Pathol Exot 69 :347–351.

    • Search Google Scholar
    • Export Citation
  • 5

    Kraivichian P, Kulkumthorn M, Yingyourd P, Akarabovorn P, Paireepai CC, 1992. Albendazole for the treatment of human gnathostomiasis. Trans R Soc Trop Med Hyg 86 :418–421.

    • Search Google Scholar
    • Export Citation
  • 6

    Nopparatana C, Setasuban P, Chaicumpa W, Tapchaisri P, 1991. Purification of Gnathostoma spinigerum specific antigen and immunodiagnosis of human gnathostomiasis. Int J Parasitol 21 :677–687.

    • Search Google Scholar
    • Export Citation
Past two years Past Year Past 30 Days
Abstract Views 22 22 4
Full Text Views 239 86 0
PDF Downloads 56 24 0
 
Membership Banner
 
 
 
Affiliate Membership Banner
 
 
Research for Health Information Banner
 
 
CLOCKSS
 
 
 
Society Publishers Coalition Banner
Save