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Calreticulin-like molecule in trophozoites of Entamoeba histolytica HM1:IMSS (Swissprot: accession P83003).
Enrique González
Enrique González
Depto. de Medicina Experimental, Facultad de Medicine, UNAM, México, DF, México.
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Guadalupe Rico
Guadalupe Rico
Depto. de Medicina Experimental, Facultad de Medicine, UNAM, México, DF, México.
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Guillermo Mendoza
Guillermo Mendoza
Depto. de Medicina Experimental, Facultad de Medicine, UNAM, México, DF, México.
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Fernando Ramos
Fernando Ramos
Depto. de Medicina Experimental, Facultad de Medicine, UNAM, México, DF, México.
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Gabriela GarcÃa
Gabriela GarcÃa
Depto. de Medicina Experimental, Facultad de Medicine, UNAM, México, DF, México.
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Patricia Morán
Patricia Morán
Depto. de Medicina Experimental, Facultad de Medicine, UNAM, México, DF, México.
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Alicia Valadez
Alicia Valadez
Depto. de Medicina Experimental, Facultad de Medicine, UNAM, México, DF, México.
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Emma I Melendro
Emma I Melendro
Depto. de Medicina Experimental, Facultad de Medicine, UNAM, México, DF, México.
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Cecilia Ximénez
Cecilia Ximénez
Depto. de Medicina Experimental, Facultad de Medicine, UNAM, México, DF, México.
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In this work, we report the partial sequence of a 51 kDa protein of Entamoeba histolytica that is highly immunogenic in humans. Partial sequencing of the N-terminal end showed that 18 of the first 20 amino acid residues of the protein were identified uniquely, indicating that the final product was a homogeneous protein preparation. The N-terminal sequence that was found was: KVYFEETFENGWKXIWSKW. Comparing the 19-amino acid sequence of the protein in automated databases shows significant similarity with amino acid sequences of the calreticulin-like protein of spinach leaves (77%) and of the calreticulin precursor of Dictyostelium discoideum (60%).
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 28 | 28 | 12 |
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| PDF Downloads | 69 | 31 | 0 |