The effect of antibacterial soap on impetigo incidence, Karachi, Pakistan.

Stephen Luby National Center of Infectious Disease, Centers for Disease Control, Atlanta, Georgia 30333, USA. SLuby@cdc.gov

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Mubina Agboatwalla National Center of Infectious Disease, Centers for Disease Control, Atlanta, Georgia 30333, USA. SLuby@cdc.gov

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Beverly M Schnell National Center of Infectious Disease, Centers for Disease Control, Atlanta, Georgia 30333, USA. SLuby@cdc.gov

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Robert M Hoekstra National Center of Infectious Disease, Centers for Disease Control, Atlanta, Georgia 30333, USA. SLuby@cdc.gov

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Mohammad H Rahbar National Center of Infectious Disease, Centers for Disease Control, Atlanta, Georgia 30333, USA. SLuby@cdc.gov

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Bruce H Keswick National Center of Infectious Disease, Centers for Disease Control, Atlanta, Georgia 30333, USA. SLuby@cdc.gov

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DOI:
https://doi.org/10.4269/ajtmh.2002.67.430
Volume/Issue:
Volume 67: Issue 4
Page(s):
430–435
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We conducted a study to determine if soap containing 1.2% triclocarban would be effective in reducing the incidence of impetigo. We randomized 162 households in a low-income neighborhood of Karachi, Pakistan, to receive a regular supply of 1.2% triclocarban-containing soap (n = 81) or an identically appearing placebo (n = 81); 79 households in a nearby neighborhood were enrolled as standard practice controls. After adjustment for household clustering and covariates, the incidence of impetigo among children living in households receiving triclocarban-containing soap (1.10 episodes per 100 person-weeks) was 23% lower than in households receiving placebo soap (P = 0.28) and 43% lower than the standard habit and practice controls (P = 0.02). The routine use of triclocarban-containing soap by children living in a community with a high incidence of impetigo was associated with a reduced incidence of impetigo.

Published Online:
Oct 2002
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
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