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Comparison of methods for the rapid laboratory assessment of children with malaria.
T Planche
T Planche
Department of Infectious Diseases, St. George's Hospital Medical School, London, United Kingdom.
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S Krishna
S Krishna
Department of Infectious Diseases, St. George's Hospital Medical School, London, United Kingdom.
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M Kombila
M Kombila
Department of Infectious Diseases, St. George's Hospital Medical School, London, United Kingdom.
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K Engel
K Engel
Department of Infectious Diseases, St. George's Hospital Medical School, London, United Kingdom.
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J F Faucher
J F Faucher
Department of Infectious Diseases, St. George's Hospital Medical School, London, United Kingdom.
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E Ngou-Milama
E Ngou-Milama
Department of Infectious Diseases, St. George's Hospital Medical School, London, United Kingdom.
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P G Kremsner
P G Kremsner
Department of Infectious Diseases, St. George's Hospital Medical School, London, United Kingdom.
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Rapid diagnosis and accurate quantification of Plasmodium falciparum parasitemia are important for the management of malaria. The assessment of disease severity also depends on evaluation of metabolic indexes such as blood glucose and lactate concentrations. Here we describe an accurate and rapid alternative to conventional thick film examination (Lambaréné method). We also assess near-patient methods for measuring blood glucose (OneTouch) and lactate (Accusport). The accuracy of the Lambaréné method is similar to that of thin films. Results from the OneTouch glucose meter also are in good agreement with a YSI 2300 reference meter. Overall, the Accusport lactate meter agrees poorly with the YSI 2300 reference meter. However, the sensitivity and specificity to detect hyperlactatemia (blood lactate > or = 5 mmol/L) are 0.94 and 0.98, respectively.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 61 | 61 | 23 |
| Full Text Views | 556 | 162 | 4 |
| PDF Downloads | 220 | 70 | 4 |