| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 604 | 293 | 21 |
| Full Text Views | 235 | 2 | 0 |
| PDF Downloads | 114 | 3 | 0 |
Development of a serologic assay to detect Taenia solium taeniasis.
P P Wilkins
P P Wilkins
Immunology Branch, Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3724, USA.
Search for other papers by P P Wilkins in
Current site
Google Scholar
PubMed
Search for other papers by P P Wilkins in
Current site
Google Scholar
PubMed
J C Allan
J C Allan
Immunology Branch, Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3724, USA.
Search for other papers by J C Allan in
Current site
Google Scholar
PubMed
Search for other papers by J C Allan in
Current site
Google Scholar
PubMed
M Verastegui
M Verastegui
Immunology Branch, Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3724, USA.
Search for other papers by M Verastegui in
Current site
Google Scholar
PubMed
Search for other papers by M Verastegui in
Current site
Google Scholar
PubMed
M Acosta
M Acosta
Immunology Branch, Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3724, USA.
Search for other papers by M Acosta in
Current site
Google Scholar
PubMed
Search for other papers by M Acosta in
Current site
Google Scholar
PubMed
A G Eason
A G Eason
Immunology Branch, Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3724, USA.
Search for other papers by A G Eason in
Current site
Google Scholar
PubMed
Search for other papers by A G Eason in
Current site
Google Scholar
PubMed
H H Garcia
H H Garcia
Immunology Branch, Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3724, USA.
Search for other papers by H H Garcia in
Current site
Google Scholar
PubMed
Search for other papers by H H Garcia in
Current site
Google Scholar
PubMed
A E Gonzalez
A E Gonzalez
Immunology Branch, Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3724, USA.
Search for other papers by A E Gonzalez in
Current site
Google Scholar
PubMed
Search for other papers by A E Gonzalez in
Current site
Google Scholar
PubMed
R H Gilman
R H Gilman
Immunology Branch, Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3724, USA.
Search for other papers by R H Gilman in
Current site
Google Scholar
PubMed
Search for other papers by R H Gilman in
Current site
Google Scholar
PubMed
V C Tsang
V C Tsang
Immunology Branch, Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3724, USA.
Search for other papers by V C Tsang in
Current site
Google Scholar
PubMed
Search for other papers by V C Tsang in
Current site
Google Scholar
PubMed
We developed a serologic assay to identify adult Taenia solium tapeworm carriers using excretory/secretory (TSES) antigens collected from in vitro cultured T. solium tapeworms. To identify taeniasis-specific antigens we used an immunoblot assay with serum samples from T. solium tapeworm carriers and cysticercosis patients. Antigens were identified that reacted with antibodies present in serum samples from taeniasis cases and not with those from cysticercosis patients. Using serum samples collected from persons with confirmed T. solium tapeworm infections, the test was determined to be 95% (69 of 73) sensitive. Serum samples (n = 193) from persons with other parasitic infections, including T. saginata tapeworm infections, do not contain cross-reacting antibodies to TSES, indicating that the assay is 100% specific. These data suggest that the immunoblot assay using TSES antigens can be used to identify persons with current or recent T. solium tapeworm infections and provides a new, important tool for epidemiologic purposes, including control and prevention strategies.
Author Notes
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 604 | 293 | 21 |
| Full Text Views | 235 | 2 | 0 |
| PDF Downloads | 114 | 3 | 0 |