Resistance of Plasmodium Malariae to Pyrimethamine (Daraprim)

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  • Public Health Service, National Institutes of Health, National Institute of Allergy and Infectious Diseases


Plasmodium malariae (USPHS Strain) has developed resistance to pyrimethamine (Daraprim®) where the amount of drug given was greater than that recommended for suppression.

Author Notes

Laboratory of Tropical Diseases, P. O. Box 717, Columbia, South Carolina.