GB virus C/hepatitis G virus infection among Colombian native Indians.

Y Tanaka Second Department of Medicine, Nagoya City University Medical School, Nagoya, Japan.

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M Mizokami Second Department of Medicine, Nagoya City University Medical School, Nagoya, Japan.

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E Orito Second Department of Medicine, Nagoya City University Medical School, Nagoya, Japan.

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K Ohba Second Department of Medicine, Nagoya City University Medical School, Nagoya, Japan.

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T Nakano Second Department of Medicine, Nagoya City University Medical School, Nagoya, Japan.

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T Kato Second Department of Medicine, Nagoya City University Medical School, Nagoya, Japan.

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Y Kondo Second Department of Medicine, Nagoya City University Medical School, Nagoya, Japan.

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X Ding Second Department of Medicine, Nagoya City University Medical School, Nagoya, Japan.

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R Ueda Second Department of Medicine, Nagoya City University Medical School, Nagoya, Japan.

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S Sonoda Second Department of Medicine, Nagoya City University Medical School, Nagoya, Japan.

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K Tajima Second Department of Medicine, Nagoya City University Medical School, Nagoya, Japan.

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T Miura Second Department of Medicine, Nagoya City University Medical School, Nagoya, Japan.

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M Hayami Second Department of Medicine, Nagoya City University Medical School, Nagoya, Japan.

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DOI:
https://doi.org/10.4269/ajtmh.1998.59.462
Volume/Issue:
Volume 59: Issue 3
Page(s):
462–467
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To elucidate the prevalence of GB virus C/hepatitis G virus (GBV-C/HGV) infection in Colombian native Indians, serum GBV-C/HGV RNA was assayed in 163 native Indians and 67 members of the general population in Colombia. The native Indians (males:females = 40:123) and the members of the general population (males:females = 20:47) were tested by reverse transcription-semi-nested polymerase chain reaction. Of the 163 native Indians, 10 (6.1%) were positive for GBV-C/HGV RNA, compared with one (1.5%) of 67 from the general population. All Indians were negative for hepatitis B surface antigen and antibody to hepatitis C virus. Of 10 Indians with GBV-C/HGV RNA, the genotype of nine subjects was the Asian type. These data indicated that 1) the prevalence of GBV-C/HGV RNA in Colombian native Indians is high, and 2) GBV-C/HGV was probably brought from Asia and inherited for generations in some native Indian groups.

Author Notes

Published Online:
Sep 1998
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
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