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Evaluation of the Kato-Katz Thick Smear and Formal Ether Sedimentation Techniques for Quantitative Diagnosis of Schistosoma mansoni Infection
A. Ebrahim
A. Ebrahim
Department of Tropical Health, High Institute of Public Health, Alexandria University, Alexandria, Egypt
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H. El-Morshedy
H. El-Morshedy
Department of Tropical Health, High Institute of Public Health, Alexandria University, Alexandria, Egypt
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E. Omer
E. Omer
Department of Tropical Health, High Institute of Public Health, Alexandria University, Alexandria, Egypt
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S. El-Daly
S. El-Daly
Department of Tropical Health, High Institute of Public Health, Alexandria University, Alexandria, Egypt
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R. Barakat
R. Barakat
Department of Tropical Health, High Institute of Public Health, Alexandria University, Alexandria, Egypt
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The present study compared the Kato-Katz thick smear and formol ether sedimentation techniques in the diagnosis of Schistosoma mansoni infections. A stool specimen was collected from 915 individuals representing a high prevalence community (63.3%) and from 471 individuals representing a relatively low prevalence village (40%). The overall sensitivity of a single Kato-Katz smear was 70.8%, and it increased with each additional slide to reach 91.7% on examining four smears. However, the sensitivity was 83.3% when using the formol ether sedimentation technique. In terms of quantitative analysis, the geometric mean egg count was 94 eggs per gram (epg) of stool by two Kato-Katz smears, and 43 epg by the sedimentation technique. This means that more than 50% of eggs were missed when using the sedimentation technique, a fact that should be taken into consideration when relating infection level with morbidity.
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| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 4917 | 741 | 260 |
| Full Text Views | 37 | 4 | 0 |
| PDF Downloads | 42 | 6 | 0 |