Molecular Investigation of a Multisource Outbreak of Crimeancongo Hemorrhagic Fever in the United Arab Emirates

Luis L. Rodriguez Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Ministry of Health, Atlanta, Georgia

Search for other papers by Luis L. Rodriguez in
Current site
Google Scholar
PubMed Close
,
Gary O. Maupin Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Ministry of Health, Atlanta, Georgia

Search for other papers by Gary O. Maupin in
Current site
Google Scholar
PubMed Close
,
Thomas G. Ksiazek Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Ministry of Health, Atlanta, Georgia

Search for other papers by Thomas G. Ksiazek in
Current site
Google Scholar
PubMed Close
,
Pierre E. Rollin Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Ministry of Health, Atlanta, Georgia

Search for other papers by Pierre E. Rollin in
Current site
Google Scholar
PubMed Close
,
Ali S. Khan Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Ministry of Health, Atlanta, Georgia

Search for other papers by Ali S. Khan in
Current site
Google Scholar
PubMed Close
,
Tino F. Schwarz Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Ministry of Health, Atlanta, Georgia

Search for other papers by Tino F. Schwarz in
Current site
Google Scholar
PubMed Close
,
Richard S. Lofts Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Ministry of Health, Atlanta, Georgia

Search for other papers by Richard S. Lofts in
Current site
Google Scholar
PubMed Close
,
Jonathan F. Smith Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Ministry of Health, Atlanta, Georgia

Search for other papers by Jonathan F. Smith in
Current site
Google Scholar
PubMed Close
,
Abdul M. Noor Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Ministry of Health, Atlanta, Georgia

Search for other papers by Abdul M. Noor in
Current site
Google Scholar
PubMed Close
,
Clarence J. Peters Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Ministry of Health, Atlanta, Georgia

Search for other papers by Clarence J. Peters in
Current site
Google Scholar
PubMed Close
, and
Stuart T. Nichol Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Ministry of Health, Atlanta, Georgia

Search for other papers by Stuart T. Nichol in
Current site
Google Scholar
PubMed Close
DOI:
https://doi.org/10.4269/ajtmh.1997.57.512
Volume/Issue:
Volume 57: Issue 5
Page(s):
512–518
Restricted access
Get Permissions

During the investigation of an outbreak of Crimean-Congo hemorrhagic fever (CCHF) in the United Arab Emirates (UAE) between 1994 and 1995, blood samples from suspected CCHF cases and ticks collected from livestock were tested for CCHF virus by antigen-capture ELISA and by a reverse transcription-polymerase chain reaction. Phylogenetic analysis of partial small (S) segment nucleotide sequences from four ticks and five human samples showed that with one exception, all the human and tick viruses clustered along with samples from Pakistan and Madagascar in one distinct lineage. Within this lineage, sequences from the UAE patients were identical or closely related to those from three Hyalomma spp. ticks obtained from livestock recently imported from Somalia. Another sequence from a UAE patient was more closely related to a CCHF virus from Nigeria. These data indicate that the 1994–1995 CCHF epidemic in the UAE was a multisource outbreak possibly associated with importation of CCHF virus-infected livestock and ticks.

Author Notes

Copyright:
Copyright © 1997 by The American Society of Tropical Medicine and Hygiene 1997
Published Online:
Nov 1997
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
Past two years Past Year Past 30 Days
Abstract Views 2841 1819 160
Full Text Views 55 6 0
PDF Downloads 75 10 0
 

 

 

 
 
Affiliate Membership Banner
 
 
Research for Health Information Banner
 
 
CLOCKSS
 
 
 
Society Publishers Coalition Banner
Save