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Short Report: Rosette Formation in Plasmodium ovale Infection
Brian J. Angus
Brian J. Angus
Faculty of Tropical Medicine, and Department of Pathobiology, Faculty of Science, Mahidol University, Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Bangkok, Thailand
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Kesinee Thanikkul
Kesinee Thanikkul
Faculty of Tropical Medicine, and Department of Pathobiology, Faculty of Science, Mahidol University, Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Bangkok, Thailand
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Kamolrat Silamut
Kamolrat Silamut
Faculty of Tropical Medicine, and Department of Pathobiology, Faculty of Science, Mahidol University, Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Bangkok, Thailand
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Nicholas J. White
Nicholas J. White
Faculty of Tropical Medicine, and Department of Pathobiology, Faculty of Science, Mahidol University, Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Bangkok, Thailand
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Rachanee Udomsangpetch
Rachanee Udomsangpetch
Faculty of Tropical Medicine, and Department of Pathobiology, Faculty of Science, Mahidol University, Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Bangkok, Thailand
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Red blood cells infected by mature stages of Plasmodium ovale obtained from a 56-year-old Thai patient formed rosettes readily with uninfected erythrocytes. Ex vivo, the ring stage-infected erythrocytes matured well under the in vitro conditions used for P. falciparum culture, and the infected erythrocytes formed rosettes when the parasites became mature trophozoites. These rosettes were stable and remained intact until completion of schizogony. Plasmodium ovale rosettes were similar to those formed by P. falciparum- and P. vivax-infected erythrocytes. Rosette formation appears to be a common property of three species of human plasmodia.
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| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 855 | 533 | 29 |
| Full Text Views | 18 | 4 | 1 |
| PDF Downloads | 19 | 7 | 2 |