| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1656 | 782 | 22 |
| Full Text Views | 90 | 16 | 8 |
| PDF Downloads | 91 | 17 | 3 |
The Epidemiology of Dengue Virus Infection among Urban, Jungle, and Rural Populations in the Amazon Region of Peru
Curtis G. Hayes
Curtis G. Hayes
U.S. Naval Medical Research Institute, U.S. Naval Medical Research Institute Detachment, Bethesda, Maryland, Peru
Search for other papers by Curtis G. Hayes in
Current site
Google Scholar
PubMed
Search for other papers by Curtis G. Hayes in
Current site
Google Scholar
PubMed
Irving A. Phillips
Irving A. Phillips
U.S. Naval Medical Research Institute, U.S. Naval Medical Research Institute Detachment, Bethesda, Maryland, Peru
Search for other papers by Irving A. Phillips in
Current site
Google Scholar
PubMed
Search for other papers by Irving A. Phillips in
Current site
Google Scholar
PubMed
Johnny D. Callahan
Johnny D. Callahan
U.S. Naval Medical Research Institute, U.S. Naval Medical Research Institute Detachment, Bethesda, Maryland, Peru
Search for other papers by Johnny D. Callahan in
Current site
Google Scholar
PubMed
Search for other papers by Johnny D. Callahan in
Current site
Google Scholar
PubMed
Walter F. Griebenow
Walter F. Griebenow
U.S. Naval Medical Research Institute, U.S. Naval Medical Research Institute Detachment, Bethesda, Maryland, Peru
Search for other papers by Walter F. Griebenow in
Current site
Google Scholar
PubMed
Search for other papers by Walter F. Griebenow in
Current site
Google Scholar
PubMed
Kenneth C. Hyams
Kenneth C. Hyams
U.S. Naval Medical Research Institute, U.S. Naval Medical Research Institute Detachment, Bethesda, Maryland, Peru
Search for other papers by Kenneth C. Hyams in
Current site
Google Scholar
PubMed
Search for other papers by Kenneth C. Hyams in
Current site
Google Scholar
PubMed
Shuenn-Jue Wu
Shuenn-Jue Wu
U.S. Naval Medical Research Institute, U.S. Naval Medical Research Institute Detachment, Bethesda, Maryland, Peru
Search for other papers by Shuenn-Jue Wu in
Current site
Google Scholar
PubMed
Search for other papers by Shuenn-Jue Wu in
Current site
Google Scholar
PubMed
Douglas M. Watts
Douglas M. Watts
U.S. Naval Medical Research Institute, U.S. Naval Medical Research Institute Detachment, Bethesda, Maryland, Peru
Search for other papers by Douglas M. Watts in
Current site
Google Scholar
PubMed
Search for other papers by Douglas M. Watts in
Current site
Google Scholar
PubMed
The first confirmed outbreak of dengue fever in Peru occurred during 1990 in Iquitos, a city of approximately 300,000 residents in the Amazon region. Because of the apparent establishment of endemic transmission of this mosquito-borne viral disease following the outbreak, epidemiologic studies were initiated in 1992. Blood specimens and data on demographic, environmental, and medical history factors were collected from volunteers in an urban sector of Iquitos, in a rural area on the outskirts of Iquitos, and in three nearby jungle communities. A follow-up blood specimen was obtained approximately one year later from a sample of subjects. Sera were tested for dengue IgG antibody by an enzyme-linked immunosorbent assay, and specificity was verified using a plaque-reduction neutralization test. Dengue antibody prevalence was 66% in the urban population, 26% in the rural population, and 32–67% in the three jungle areas. A significant association was found between age and antibody prevalence, with a steady increase in prevalence from 18% among subjects less than five years of age to greater than 90% for subjects more than 50 years old. Increased antibody prevalence also was associated with urban and jungle residence and with a piped source of household drinking water. Seroconversions were documented in four of five surveyed communities. These results indicate that dengue virus transmission continues in and around Iquitos and suggest that transmission also occurred prior to the 1990 epidemic.
Author Notes
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1656 | 782 | 22 |
| Full Text Views | 90 | 16 | 8 |
| PDF Downloads | 91 | 17 | 3 |