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Gametocytocidal Activity of α/β Arteether by the Oral Route of Administration
Renu Tripathi
Renu Tripathi
Division of Microbiology, Central Drug Research Institute, National Institute of Immunology, Lucknow, India
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G. P. Dutta
G. P. Dutta
Division of Microbiology, Central Drug Research Institute, National Institute of Immunology, Lucknow, India
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R. A. Vishwakarma
R. A. Vishwakarma
Division of Microbiology, Central Drug Research Institute, National Institute of Immunology, Lucknow, India
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Arteether (α/β) (a mixture of α and β enantioners) has been reported to possess gametocytocidal activity against Plasmodium cynomolgi B when the drug is given by the intramuscular route, but it would be preferable to use oral route therapy for gametocyte carriers. This is a report of a study of the gametocytocidal action of arteether administered by the oral route. The results indicate high levels of activity at 10 mg/kg in a single dose or in two divided doses when given orally.
| Past two years | Past Year | Past 30 Days | |
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| Abstract Views | 216 | 73 | 4 |
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