A Case Report of Colonic Ileus due to Eosinophilic Nodular Lesions caused by Gnathostoma doloresi Infection

Kohji Seguchi Second Department of Pathology, and Department of Parasitology, Miyazaki Medical College, Department of Surgery, Konan Hospital, Kiyotake, Miyazaki, Japan

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Masahiro Matsuno Second Department of Pathology, and Department of Parasitology, Miyazaki Medical College, Department of Surgery, Konan Hospital, Kiyotake, Miyazaki, Japan

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Hiroaki Kataoka Second Department of Pathology, and Department of Parasitology, Miyazaki Medical College, Department of Surgery, Konan Hospital, Kiyotake, Miyazaki, Japan

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Takahiko Kobayashi Second Department of Pathology, and Department of Parasitology, Miyazaki Medical College, Department of Surgery, Konan Hospital, Kiyotake, Miyazaki, Japan

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Haruhiko Maruyama Second Department of Pathology, and Department of Parasitology, Miyazaki Medical College, Department of Surgery, Konan Hospital, Kiyotake, Miyazaki, Japan

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Hiroshi Itoh Second Department of Pathology, and Department of Parasitology, Miyazaki Medical College, Department of Surgery, Konan Hospital, Kiyotake, Miyazaki, Japan

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Masashi Koono Second Department of Pathology, and Department of Parasitology, Miyazaki Medical College, Department of Surgery, Konan Hospital, Kiyotake, Miyazaki, Japan

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Yukifumi Nawa Second Department of Pathology, and Department of Parasitology, Miyazaki Medical College, Department of Surgery, Konan Hospital, Kiyotake, Miyazaki, Japan

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Gnathostomiasis is primarily a disease of the skin characterized as creeping eruption or mobile erythema. However, larval Gnathostoma sometimes migrate into an unexpected site to elicit serious illness. Here we describe a case of colonic ileus caused by Gnathostoma doloresi. The patient was a 57-year-old man living in Miyazaki Prefecture, Japan, which is known as an area endemic for this parasite. One week after having eaten a few slices of the flesh of a snake (Agkistrodon halys), he developed severe abdominal pain. An abdominal radiograph revealed multiple gas-fluid levels with a distended bowel of an inverted U shape. A barium enema revealed a tumor in the ascending colon near the hepatic flexure that was surgically removed by simple colonic resection. An oblique section of a parasite surrounded by massive infiltration of eosinophils was found by postoperative histopathologic examination. The entire body of the advanced third-stage larva of G. doloresi was dissected from a specimen-embedded paraffin block.

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