Emergence of Buruli Ulcer Disease in the Daloa Region of Cote D'Ivoire

Barbara J. Marston Childhood and Respiratory Diseases Branch and Biostatistics and Information Management Branch, Division of Bacterial and Mycotic Diseases, and Division of HIV/AIDS, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Projet Retro-CI, Secteur Sante Rurale, Ministere de la Sante et de la Protection Sociale, Service Dermatologie, University of Treichville, Atlanta, Georgia

Search for other papers by Barbara J. Marston in
Current site
Google Scholar
PubMed Close
,
Mamadou O. Diallo Childhood and Respiratory Diseases Branch and Biostatistics and Information Management Branch, Division of Bacterial and Mycotic Diseases, and Division of HIV/AIDS, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Projet Retro-CI, Secteur Sante Rurale, Ministere de la Sante et de la Protection Sociale, Service Dermatologie, University of Treichville, Atlanta, Georgia

Search for other papers by Mamadou O. Diallo in
Current site
Google Scholar
PubMed Close
,
C. Robert Horsburgh Jr Childhood and Respiratory Diseases Branch and Biostatistics and Information Management Branch, Division of Bacterial and Mycotic Diseases, and Division of HIV/AIDS, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Projet Retro-CI, Secteur Sante Rurale, Ministere de la Sante et de la Protection Sociale, Service Dermatologie, University of Treichville, Atlanta, Georgia

Search for other papers by C. Robert Horsburgh Jr in
Current site
Google Scholar
PubMed Close
,
Idrissa Diomande Childhood and Respiratory Diseases Branch and Biostatistics and Information Management Branch, Division of Bacterial and Mycotic Diseases, and Division of HIV/AIDS, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Projet Retro-CI, Secteur Sante Rurale, Ministere de la Sante et de la Protection Sociale, Service Dermatologie, University of Treichville, Atlanta, Georgia

Search for other papers by Idrissa Diomande in
Current site
Google Scholar
PubMed Close
,
Mathieu Z. Saki Childhood and Respiratory Diseases Branch and Biostatistics and Information Management Branch, Division of Bacterial and Mycotic Diseases, and Division of HIV/AIDS, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Projet Retro-CI, Secteur Sante Rurale, Ministere de la Sante et de la Protection Sociale, Service Dermatologie, University of Treichville, Atlanta, Georgia

Search for other papers by Mathieu Z. Saki in
Current site
Google Scholar
PubMed Close
,
Jean-Marie Kanga Childhood and Respiratory Diseases Branch and Biostatistics and Information Management Branch, Division of Bacterial and Mycotic Diseases, and Division of HIV/AIDS, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Projet Retro-CI, Secteur Sante Rurale, Ministere de la Sante et de la Protection Sociale, Service Dermatologie, University of Treichville, Atlanta, Georgia

Search for other papers by Jean-Marie Kanga in
Current site
Google Scholar
PubMed Close
,
G'Bery Patrice Childhood and Respiratory Diseases Branch and Biostatistics and Information Management Branch, Division of Bacterial and Mycotic Diseases, and Division of HIV/AIDS, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Projet Retro-CI, Secteur Sante Rurale, Ministere de la Sante et de la Protection Sociale, Service Dermatologie, University of Treichville, Atlanta, Georgia

Search for other papers by G'Bery Patrice in
Current site
Google Scholar
PubMed Close
,
Harvey B. Lipman Childhood and Respiratory Diseases Branch and Biostatistics and Information Management Branch, Division of Bacterial and Mycotic Diseases, and Division of HIV/AIDS, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Projet Retro-CI, Secteur Sante Rurale, Ministere de la Sante et de la Protection Sociale, Service Dermatologie, University of Treichville, Atlanta, Georgia

Search for other papers by Harvey B. Lipman in
Current site
Google Scholar
PubMed Close
,
Stephen M. Ostroff Childhood and Respiratory Diseases Branch and Biostatistics and Information Management Branch, Division of Bacterial and Mycotic Diseases, and Division of HIV/AIDS, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Projet Retro-CI, Secteur Sante Rurale, Ministere de la Sante et de la Protection Sociale, Service Dermatologie, University of Treichville, Atlanta, Georgia

Search for other papers by Stephen M. Ostroff in
Current site
Google Scholar
PubMed Close
, and
Robert C. Good Childhood and Respiratory Diseases Branch and Biostatistics and Information Management Branch, Division of Bacterial and Mycotic Diseases, and Division of HIV/AIDS, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Projet Retro-CI, Secteur Sante Rurale, Ministere de la Sante et de la Protection Sociale, Service Dermatologie, University of Treichville, Atlanta, Georgia

Search for other papers by Robert C. Good in
Current site
Google Scholar
PubMed Close
DOI:
https://doi.org/10.4269/ajtmh.1995.52.219
Volume/Issue:
Volume 52: Issue 3
Page(s):
219–224
Restricted access
Get Permissions

Recent reports have suggested increases in Buruli ulcer (BU), an infection caused by Mycobacterium ulcerans in west Africa. In 1991, we conducted surveillance for BU in a rural area of Cote d'Ivoire and identified 312 cases of active or healed ulceration. A case-control study was then performed to investigate risk factors for this infection. The rate of illness did not appear to differ between males and females (5.2% versus 7.5%; P = 0.11). The highest rate of illness was seen in the 10–14-year-old age group (143 cases per 1,000 population). New cases increased more than three-fold between 1987 and 1991, and local prevalence of BU was as high as 16.3%. Twenty-six percent of persons with healed ulcers had chronic functional disability. Participation in farming activities near the main river in the region was identified in the case-control study as a risk factor for infection (odds ratio [OR] for each 10-min decrease in walking distance between the fields and the river = 1.52, 95% confidence interval [CI] 1.01, 2.28, P = 0.046). Wearing long pants was protective (OR 0.20, 95% CI 0.06, 0.62, P < 0.005). We conclude that the incidence of BU is increasing rapidly in Cote d'Ivoire. Specific causes of this increase were not identified, but wearing protective clothing appeared to decrease the risk of disease.
Published Online:
Mar 1995
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
Past two years Past Year Past 30 Days
Abstract Views 807 283 19
Full Text Views 34 0 0
PDF Downloads 24 0 0
 
Membership Banner
 
 
 
Affiliate Membership Banner
 
 
Research for Health Information Banner
 
 
CLOCKSS
 
 
 
Society Publishers Coalition Banner
Save